73 Result(s)

Article

Hematopoietic stem cell transplantation for T-cell large granular lymphocyte leukemia: a retrospective study of the European Society for Blood and Marrow Transplantation

T Marchand, T Lamy, H Finel, W Arcese, S Choquet, J Finke, A Huynh, G Irrera… in Leukemia (2016)

Article

Allogeneic hematopoietic cell transplantation as curative therapy for non-transformed follicular lymphomas

Allogeneic hematopoietic cell transplantation (HCT) offers the chance of cure for patients with non-transformed follicular lymphoma (FL), but is associated with the risk of non-relapse mortality (NRM). The aim...

F Heinzelmann, W Bethge, D W Beelen, M Engelhard, N Kröger… in Bone Marrow Transplantation (2016)

Article

Prognostic impact of progression to induction chemotherapy and prior paclitaxel therapy in patients with germ cell tumors receiving salvage high-dose chemotherapy in the last 10 years: a study of the European Society for Blood and Marrow Transplantation Solid Tumors Working Party

Little is known about the prognostic impact of prior paclitaxel therapy and response to induction chemotherapy defined as the regimen preceding high-dose chemotherapy (HDCT) for the salvage therapy of advanced...

A Necchi, R Miceli, M Bregni, C Bokemeyer, L A Berger… in Bone Marrow Transplantation (2016)

Article

Autologous stem cell transplantation for relapsed/refractory diffuse large B-cell lymphoma: efficacy in the rituximab era and comparison to first allogeneic transplants. A report from the EBMT Lymphoma Working Party

In the era of chemoimmunotherapy, the optimal treatment paradigm for relapsed and refractory diffuse large B-cell lymphoma has been challenged. We reviewed the outcome of standard salvage therapy with an autol...

S P Robinson, A Boumendil, H Finel, D Blaise, X Poiré… in Bone Marrow Transplantation (2016)

Article

Thiotepa-based high-dose therapy for autologous stem cell transplantation in lymphoma: a retrospective study from the EBMT

Clinical information about thiotepa-based autologous stem cell transplantation (auto-SCT) outside the primary central nervous system lymphoma (PCNSL) field is sparse. In this registry-based retrospective study...

L Sellner, A Boumendil, H Finel, S Choquet, G de Rosa… in Bone Marrow Transplantation (2016)

Article

Second reduced intensity conditioning allogeneic transplant as a rescue strategy for acute leukaemia patients who relapse after an initial RIC allogeneic transplantation: analysis of risk factors and treatment outcomes

Limited therapeutic options are available after relapse of acute leukaemia following first reduced intensity conditioning haematopoietic stem cell transplantation (RIC1). A retrospective study on European Soci...

R Vrhovac, M Labopin, F Ciceri, J Finke, E Holler, J Tischer… in Bone Marrow Transplantation (2016)

Article

Second allogeneic transplantation for relapse of malignant disease: retrospective analysis of outcome and predictive factors by the EBMT

In patients treated with allogeneic stem cell transplantation (SCT) for malignant disease who suffer from a relapse after the transplantation, the role of second allogeneic SCT is often uncertain. In a retrosp...

T Ruutu, L C de Wreede, A van Biezen, R Brand, M Mohty… in Bone Marrow Transplantation (2015)

Article

p53-dependent non-coding RNA networks in chronic lymphocytic leukemia

Mutations of the tumor suppressor p53 lead to chemotherapy resistance and a dismal prognosis in chronic lymphocytic leukemia (CLL). Whereas p53 targets are used to identify patient subgroups with impaired p53 ...

C J Blume, A Hotz-Wagenblatt, J Hüllein, L Sellner, A Jethwa, T Stolz… in Leukemia (2015)

Article

Allogeneic hematopoietic stem cell transplantation for poor-risk CLL: dissecting immune-modulating strategies for disease eradication and treatment of relapse

To elucidate factors contributing to the effectiveness of allogeneic hematopoietic stem cell transplantation (alloHCT) in high-risk CLL, immune interventions, GvHD and clinical outcome of 77 consecutive patien...

M Hahn, S Böttcher, S Dietrich, U Hegenbart, M Rieger… in Bone Marrow Transplantation (2015)

Article

Indications for allo- and auto-SCT for haematological diseases, solid tumours and immune disorders: current practice in Europe, 2015

This is the sixth special report that the European Society for Blood and Marrow Transplantation regularly publishes on the current practice and indications for haematopoietic SCT for haematological diseases, s...

A Sureda, P Bader, S Cesaro, P Dreger, R F Duarte, C Dufour… in Bone Marrow Transplantation (2015)

Article

Comparison of upfront tandem autologous–allogeneic transplantation versus reduced intensity allogeneic transplantation for multiple myeloma

We performed a retrospective analysis of the European Group for Blood and Marrow Transplantation database comparing the outcomes of multiple myeloma patients who received tandem autologous followed by allogene...

F Sahebi, S Iacobelli, A V Biezen, L Volin, P Dreger… in Bone Marrow Transplantation (2015)

Article

Second allo-SCT in patients with lymphoma relapse after a first allogeneic transplantation. A retrospective study of the EBMT Lymphoma Working Party

The aim of this registry-based retrospective study was to analyze the outcome of second allogeneic hematopoietic SCT (alloHSCT_2) performed in patients with lymphoma who had relapsed after a first allogeneic t...

K Horstmann, A Boumendil, J Finke, H Finel, E Kanfer… in Bone Marrow Transplantation (2015)

Article

Epigenetic aging upon allogeneic transplantation: the hematopoietic niche does not affect age-associated DNA methylation

C I Weidner, P Ziegler, M Hahn, T H Brümmendorf, A D Ho, P Dreger, W Wagner in Leukemia (2015)

Article

Allogeneic and autologous stem cell transplantation for hepatosplenic T-cell lymphoma: a retrospective study of the EBMT Lymphoma Working Party

The objective of this registry study was to analyse the outcome of patients who underwent allogeneic or autologous haematopoietic stem cell transplantation (HSCT) for hepatosplenic T-cell lymphoma (HSTL), a ra...

A Tanase, N Schmitz, H Stein, A Boumendil, H Finel, L Castagna, D Blaise… in Leukemia (2015)

Article

The EBMT/EMCL consensus project on the role of autologous and allogeneic stem cell transplantation in mantle cell lymphoma

The role of both autologous (autoSCT) and allogeneic stem cell transplantation (alloSCT) in the management of mantle cell lymphoma (MCL) remains to be clarified. We conducted a consensus project using the RAND...

S Robinson, P Dreger, D Caballero, P Corradini, C Geisler, M Ghielmini… in Leukemia (2015)

Article

Sensitivity of hematological malignancies to graft-versus-host effects: an EBMT megafile analysis

After allogeneic stem cell transplantation, graft-versus-host disease (GvHD) occurs through recognition of histocompatibility mismatches by donor T lymphocytes. The same mechanism operates in eliminating malig...

M Stern, L C de Wreede, R Brand, A van Biezen, P Dreger, M Mohty, T M de Witte… in Leukemia (2014)

Article

Outcome of patients with HTLV-1-associated adult T-cell leukemia/lymphoma after SCT: a retrospective study by the EBMT LWP

Adult T-cell leukemia/lymphoma (ATL) carries a dismal prognosis. Experience with allo-SCT for ATL appears encouraging but is limited to Japanese series. This retrospective analysis of the EBMT registry reveale...

A Bazarbachi, K Cwynarski, A Boumendil, H Finel, P Fields… in Bone Marrow Transplantation (2014)

Article

Matched unrelated donor allogeneic transplantation provides comparable long-term outcome to HLA-identical sibling transplantation in relapsed diffuse large B-cell lymphoma

The objective of this retrospective analysis was to compare outcomes of patients with diffuse large B-cell lymphoma (DLBCL) who received either a matched sibling (sib) or an unrelated donor (URD) allogeneic he...

I Avivi, C Canals, J-P Vernant, G Wulf, A Nagler, O Hermine… in Bone Marrow Transplantation (2014)