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181 Result(s)
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Article
Inversion of Subsidence Parameters and Prediction of Surface Dynamics under Insufficient Mining
By combining the advantages of InSAR, Probabilistic Integral Method and Genetic Algorithm, an improved method for dynamic prediction of probability integral parameters is proposed to realize subsidence inversi...
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Open AccessNeutrophils in triple-negative breast cancer: an underestimated player with increasingly recognized importance
Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer, with limited therapeutic options readily available. Immunotherapy such as immune checkpoint inhibition has been investigated in...
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Open AccessChronic UCN2 treatment desensitizes CRHR2 and improves insulin sensitivity
Urocortin 2 (UCN2) acts as a ligand for the G protein-coupled receptor corticotropin-releasing hormone receptor 2 (CRHR2). UCN2 has been reported to improve or worsen insulin sensitivity and glucose tolerance ...
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Open AccessUHPLC-HRMS-based metabolomic and lipidomic characterization of glioma cells in response to anlotinib
Anlotinib, as a promising oral small-molecule antitumor drug, its role in glioma has been only reported in a small number of case reports. Therefore, anlotinib has been considered as a promising candidate in g...
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Nitrogen-metabolising microorganism analysis in rapid sand filters from drinking water treatment plant
Sand filters (SFs) are common treatment processes for nitrogen pollutant removal in drinking water treatment plants (DWTPs). However, the mechanisms on the nitrogen-cycling role of SFs are still unclear. In th...
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Targeted delivery of nuclear targeting probe for bladder cancer using cyclic pentapeptide c(RGDfK) and acridine orange
Both cyclic pentapeptide c(RGDfK) and acridine orange (AO) exhibit antitumor effects and cell permeability. This study aimed to evaluate the nuclear targeting efficiency and safety of the nuclear targeting pro...
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Article
Effects of probiotics on hypertension
Emerging data have suggested that probiotics had good potential in regulating intestinal flora and preventing hypertension. Some studies in human and animal models have demonstrated probiotic intervention coul...
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Open AccessThe MING proposal at SHINE: megahertz cavity enhanced X-ray generation
The cavity-based X-ray free-electron laser (XFEL) has promise in producing fully coherent pulses with a bandwidth of a few meV and very stable intensity, whereas the currently existing self-amplified spontaneo...
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Article
Risk factors for postoperative urinary retention in patients undergoing colorectal surgery: a systematic review and meta-analysis
Postoperative urinary retention (POUR) is a common complication following colorectal surgery. The incidence of POUR among colorectal surgery patients varies widely, and the risk factors and outcomes of POUR ar...
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Article
Effect of antiplatelet treatment on aneurysmal subarachnoid hemorrhage patients after endovascular treatment: a systematic review with meta-analysis
Antiplatelet treatment (APT) has been reported to be used in some patients with aneurysmal subarachnoid hemorrhage (aSAH) after endovascular treatment, but there is controversy among different studies regardin...
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Article
Effect of groove-textured 4H-SiC on the deformation behavior of deposited film using molecular dynamics
In this paper, the mechanical behavior of deposited film with groove textured is studied in detail by nanoindentation. The results show that the groove textured-
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Article
Open AccessPublisher Correction: Visualizing translation dynamics at atomic detail inside a bacterial cell
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Article
The Effect of External Electric Field on the Conformational Integrity of Trypsin Inhibitor: A Molecular Model Study
The folding and unfolding of proteins under exogenous perturbation is still a topic of great interest. People have conducted in-depth studies on the biological and health effects of electrostatic fields. In th...
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Open AccessVisualizing translation dynamics at atomic detail inside a bacterial cell
Translation is the fundamental process of protein synthesis and is catalysed by the ribosome in all living cells1. Here we use advances in cryo-electron tomography and sub-tomogram analysis2,3 to visualize the st...
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Article
Kinetic triplet from low-temperature carburization and carbon deposition reactions
Carbon deposition reaction is unfavorable for smooth operation of blast furnace, while the product of carburization reaction is a superior iron-bearing raw material in non-blast furnace routes. The kinetic tri...
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Article
Open AccessCDH1 overexpression predicts bladder cancer from early stage and inversely correlates with immune infiltration
Bladder cancer (BC) seriously endangers public health, but effective biomarkers for BC diagnosis, particularly in the early stage, are still lacking. Identification of reliable biomarkers associated with early...
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Article
Investigation of Molecular Diffusion at Block Copolymer Thin Films Using Maximum Entropy Method-Based Fluorescence Correlation Spectroscopy and Single Molecule Tracking
Fluorescence correlation spectroscopy (FCS) has been widely used to investigate molecular diffusion behavior in various samples. The use of the maximum entropy method (MEM) for FCS data analysis provides a uni...
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Open AccessRapid screening for antigenic characterization of GII.17 norovirus strains with variations in capsid gene
The emergence of the novel GII.17 Kawasaki 2014 norovirus variant raising the interest of the public, has replaced GII.4 as the predominant cause of noroviruses outbreaks in East Asia during 2014–2015. Antigen...
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Article
Open AccessEffects of organic fertilizer proportion on the distribution of soil aggregates and their associated organic carbon in a field mulched with gravel
Gravel and sand mulching is an indigenous technology that has been used for increasing soil temperature and improving crop yield and water use efficiency for at least 300 years in northwestern China. However, ...
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Article
Open AccessSTAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway
Compelling evidences have revealed the emerging role of ferroptosis in the pathophysiological process of acute lung injury (ALI), but its modulation is not clear. Here, we identified that STAT6 acted as a crit...