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630 Result(s)
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Article
Open AccessUpregulated dual oxidase 1-induced oxidative stress and caspase-1-dependent pyroptosis reflect the etiologies of heart failure
Oxidative stress is implicated in the pathogenesis of heart failure. Dual oxidase 1 (DUOX1) might be important in heart failure development through its mediating role in oxidative stress. This study was design...
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Open AccessUnveiling the emerging role of curcumin to alleviate ochratoxin A-induced muscle toxicity in grass carp (Ctenopharyngodon idella): in vitro and in vivo studies
Ochratoxin A (OTA), a globally abundant and extremely hazardous pollutant, is a significant source of contamination in aquafeeds and is responsible for severe food pollution. The developmental toxicity of OTA ...
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Lactobacillus paracasei Jlus66 relieves DSS-induced ulcerative colitis in a murine model by maintaining intestinal barrier integrity, inhibiting inflammation, and improving intestinal microbiota structure
Ulcerative colitis (UC) is a serious health problem with increasing morbidity and prevalence worldwide. The pathogenesis of UC is complex, currently believed to be influenced by genetic factors, dysregulation ...
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Open AccessAn accurate trajectory tracking method for low-speed unmanned vehicles based on model predictive control
Trajectory tracking on a low-speed vehicle using the model predictive control (MPC) algorithm usually assumes a simple road terrain. This assumption does not correspond to the actual road situation, leading to...
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Article
Integrated Radial-axial Magnetic Bearing with Variable Permanent-Magnet Bias Flux In Situ
Bias magnetic flux plays a crucial role in the performance of active magnetic bearings. However, the bias flux produced by NdFeB or SmCo materials in traditional permanent-magnet (PM) bias bearings cannot be a...
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Open AccessAdherence and Persistence to Basal Insulin Among People with Type 2 Diabetes in Europe: A Systematic Literature Review and Meta-analysis
Diabetes is associated with a number of complications, particularly if glycaemic targets are not achieved. Glycaemic control is highly linked to treatment persistence and adherence. To understand the burden of...
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Open AccessRecent progresses in analytical method development for 210Pb in environmental and biological samples
As a decay product of uranium series, 210Pb spreads widely in the nature and imposes strong radiological and chemical toxicity. It is vital to establish reliable and efficient radioanalytical methods for 210Pb de...
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Synergistic adsorption–photocatalytic removal toward levofloxacin and methylene blue by silver phosphate/strontium ferrite/graphene oxide composite under visible light irradiation
Combination of adsorption and photocatalytic degradation is an effective strategy for rapid elimination of organic pollutants from contaminated water. Herein, in order to improve the dispersion of catalyst, in...
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Article
Quantifying the Effects of Near-Surface Viscosity on Seismic Acquisition Geometry: A case study from Chepaizi Exploration Area, Junggar Basin (NW China)
The Chepaizi Exploration Area, Junggar Basin (NW China) holds substantial importance for seismic exploration endeavors, yet it poses notable challenges due to the intricate nature of its subsurface and near-su...
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Open AccessAnalysis of risk factors of preeclampsia in pregnant women with chronic hypertension and its impact on pregnancy outcomes
To investigate the risk factors and maternal and fetal outcomes of preeclampsia after pregnancy in patients with primary chronic hypertension.
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Open Access25-hydroxycholesterol promotes proliferation and metastasis of lung adenocarcinoma cells by regulating ERβ/TNFRSF17 axis
Lung adenocarcinoma is the main type of lung cancer in women. Our previous findings have evidenced that 25-hydroxycholesterol (25-HC) promotes migration and invasion of lung adenocarcinoma cells (LAC), during ...
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Article
Application of the optimal regression-based analysis to estimate the deformation of geogrid-reinforced soil structures
The analysis of deformation plays a crucial role in the design of Geosynthetic reinforced structure (GRS) constructions. However, the publications emphasize the potential of artificial prediction algorithms in...
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Article
Open AccessFBXO32-mediated degradation of PTEN promotes lung adenocarcinoma progression
FBXO32, a member of the F-box protein family, is known to play both oncogenic and tumor-suppressive roles in different cancers. However, the functions and the molecular mechanisms regulated by FBXO32 in lung a...
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Open AccessRUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway
Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignant tumors of the head and neck. Vasculogenic mimicry (VM) is crucial for tumor growth and metastasis and refers to the formation of flu...
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Open AccessCombining ability of Egyptian cotton (Gossypium barbadense L.) reveals genetic potential for improved yield and fiber quality
As the most widely cultivated fiber crop, cotton production depends on hybridization to unlock the yield potential of current varieties. A deep understanding of genetic dissection is crucial for the cultivatio...
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Open AccessEffects of bone marrow sparing radiotherapy on acute hematologic toxicity for patients with locoregionally advanced cervical cancer: a prospective phase II randomized controlled study
To evaluate effects of bone marrow sparing (BMS) radiotherapy on decreasing the incidence of acute hematologic toxicity (HT) for locoregionally advanced cervical cancer (LACC) patients treated by pelvic irradi...
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Article
Improving Sedum plumbizincicola genetic transformation with the SpGRF4–SpGIF1 gene and the self-excision CRE/LoxP system
S. plumbizincicola genetic transformation was optimized using a self-excision molecular-assisted transformation system by integrating the SpGRF4/SpGIF1 gene with XVE and Cre/loxP.
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Article
Open AccessUltrastiff metamaterials generated through a multilayer strategy and topology optimization
Metamaterials composed of different geometrical primitives have different properties. Corresponding to the fundamental geometrical forms of line, plane, and surface, beam-, plate-, and shell-based lattice meta...
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Open AccessMultiple serum anti-glutamate receptor antibody levels in clozapine-treated/naïve patients with treatment-resistant schizophrenia
Glutamatergic function abnormalities have been implicated in the etiology of treatment-resistant schizophrenia (TRS), and the efficacy of clozapine may be attributed to its impact on the glutamate system. Rece...
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Heavy metal(loid)s transformation in dust at a lead smelting site
Emitted dust is the major contributor of heavy metal(loid)s in soils located near lead (Pb) smelters, but the mechanisms for transfer of the heavy metal(loid)s in dust are uncertain. The study systematically i...