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  1. No Access

    Article

    The validity of cost-effectiveness analyses of tight glycemic control. A systematic survey of economic evaluations of pharmacological interventions in patients with type 2 diabetes

    Currently available randomized trial evidence has shown no reductions in type 2 diabetes (T2D) complications important to patients with tight glycemic control. Yet, economic analyses consistently find tight gl...

    Francisco J. Barrera, Freddy JK. Toloza, Oscar J. Ponce in Endocrine (2021)

  2. Article

    Open Access

    Feasibility of behavioral activation group therapy in reducing depressive symptoms and improving quality of life in patients with depression: the BRAVE pilot trial

    Depression impacts the lives of millions of people worldwide. Behavioral activation (BA), derived from cognitive behavioral therapy, has the potential for improving depressive symptoms in patients with depress...

    Alessia D’Elia, Monica Bawor, Brittany B. Dennis in Pilot and Feasibility Studies (2020)

  3. No Access

    Article

    Guidelines seek unbiased recommendations

    Alexander P. Vlaar, Simon Oczkowski, Gavin J. Murphy in Intensive Care Medicine (2020)

  4. Article

    Transfusion strategies in non-bleeding critically ill adults: a clinical practice guideline from the European Society of Intensive Care Medicine

    To develop evidence-based clinical practice recommendations regarding transfusion practices in non-bleeding, critically ill adults.

    Alexander P. Vlaar, Simon Oczkowski, Sanne de Bruin in Intensive Care Medicine (2020)

  5. Article

    Open Access

    Predictors of 1-year mortality in adult lung transplant recipients: a systematic review and meta-analysis

    Upon surviving the first year post-lung transplantation, recipients can expect a median survival of 8 years. Within the first year, graft failure and multi-organ failure (possibly secondary to graft failure) a...

    Farid Foroutan, Gordon Guyatt, Erik Friesen in Systematic Reviews (2019)

  6. No Access

    Article

    Factors influencing decision making in neonatology: inhaled nitric oxide in preterm infants

    We studied decision making regarding inhaled nitric oxide (iNO) in preterm infants with Pulmonary Hypertension (PH).

    Veena Manja, Gordon Guyatt, Satyan Lakshminrusimha, Susan Jack in Journal of Perinatology (2019)

  7. No Access

    Article

    Conflicts of interest disclosure forms and management in critical care clinical practice guidelines

    Trustworthy clinical practice guidelines (CPGs) require identification and careful management of conflicts of interest (COIs) among all participants in the guideline development. Furthermore, COIs are more com...

    Waleed Alhazzani, Kimberley Lewis, Roman Jaeschke, Bram Rochwerg in Intensive Care Medicine (2018)

  8. Article

    Open Access

    Network meta-analysis: users’ guide for pediatricians

    Network meta-analysis (NMA) is a powerful analytic tool that allows simultaneous comparison between several management/treatment alternatives even when direct comparisons of the alternatives (such as the case ...

    Reem Al Khalifah, Ivan D. Florez, Gordon Guyatt, Lehana Thabane in BMC Pediatrics (2018)

  9. Article

    Open Access

    The GRADE Evidence to Decision (EtD) framework for health system and public health decisions

    To describe a framework for people making and using evidence-informed health system and public health recommendations and decisions.

    Jenny Moberg, Andrew D. Oxman, Sarah Rosenbaum in Health Research Policy and Systems (2018)

  10. Article

    Open Access

    Public health journals’ requirements for authors to disclose funding and conflicts of interest: a cross-sectional study

    Public health journals need to have clear policies for reporting the funding of studies and authors’ personal financial and non-financial conflicts of interest (COI) disclosures. This study aims to assess the ...

    Karim N. Daou, Maram B. Hakoum, Assem M. Khamis, Lama Bou-Karroum in BMC Public Health (2018)

  11. Article

    Are systematic reviews and meta-analyses still useful research? Yes

    Djillali Annane, Roman Jaeschke, Gordon Guyatt in Intensive Care Medicine (2018)

  12. No Access

    Article

    Target blood pressure for septic and vasodilatory shock: what is optimal?

    Junki Ishii, Shinichiro Ohshimo, Nobuaki Shime in Intensive Care Medicine (2018)

  13. Article

    Correction to: Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials

    Owing to an oversight by the authors, all the figures in the last column of Table 2 (upper section: Number needed to treat; lower section: Number needed to harm) in this article were given without the final di...

    Waleed Alhazzani, Fayez Alshamsi, Emilie Belley-Cote in Intensive Care Medicine (2018)

  14. Article

    Open Access

    FIT for FUNCTION: study protocol for a randomized controlled trial

    The current state of evidence suggests that community-based exercise programs are beneficial in improving impairment, function, and health status, and are greatly needed for persons with stroke. However, limit...

    Julie Richardson, Ada Tang, Gordon Guyatt, Lehana Thabane, Feng **e in Trials (2018)

  15. Article

    Open Access

    Efficacy and safety of stress ulcer prophylaxis in critically ill patients: a network meta-analysis of randomized trials

    Stress ulcer prophylaxis (SUP) is commonly prescribed in the intensive care unit. However, data from systematic reviews and conventional meta-analyses are limited by imprecision and restricted to direct compar...

    Waleed Alhazzani, Fayez Alshamsi, Emilie Belley-Cote in Intensive Care Medicine (2018)

  16. No Access

    Article

    N-of-1 Randomized Trials of Ultra-Micronized Palmitoylethanolamide in Older Patients with Chronic Pain

    Ultra-micronized palmitoylethanolamide (um-PEA) represents an attractive option for chronic pain control in complex older patients at higher risk of adverse effects with traditional analgesics.

    Federico Germini, Anna Coerezza, Luca Andreinetti, Alessandro Nobili in Drugs & Aging (2017)

  17. Article

    Open Access

    Requirements of health policy and services journals for authors to disclose financial and non-financial conflicts of interest: a cross-sectional study

    The requirements of the health policy and services journals for authors to report their financial and non-financial conflicts of interest (COI) are unclear. The present article aims to assess the requirements ...

    Assem M. Khamis, Maram B. Hakoum, Lama Bou-Karroum in Health Research Policy and Systems (2017)

  18. Article

    Open Access

    Efficacy and safety of proton pump inhibitors for stress ulcer prophylaxis in critically ill patients: a systematic review and meta-analysis of randomized trials

    The relative efficacy and safety of proton pump inhibitors (PPIs) compared to histamine-2-receptor antagonists (H2RAs) should guide their use in reducing bleeding risk in the critically ill.

    Fayez Alshamsi, Emilie Belley-Cote, Deborah Cook, Saleh A. Almenawer in Critical Care (2016)

  19. Article

    Open Access

    Behavioral activation group therapy for reducing depressive symptoms and improving quality of life: a feasibility study

    Depression is associated with a loss of productivity and noticeable personal, social, and economic decline; it affects more than 350 million people worldwide. Behavioral activation (BA), derived from cognitive...

    Zainab Samaan, Brittany B. Dennis, Lindsay Kalbfleisch in Pilot and Feasibility Studies (2016)

  20. Article

    Open Access

    International law’s effects on health and its social determinants: protocol for a systematic review, meta-analysis, and meta-regression analysis

    In recent years, there have been numerous calls for global institutions to develop and enforce new international laws. International laws are, however, often blunt instruments with many uncertain benefits, cos...

    Steven J. Hoffman, Matthew Hughsam, Harkanwal Randhawa in Systematic Reviews (2016)

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