699 Result(s)
within
English
Medicine & Public Health
Medicine/Public Health, general
Dong-**ng Wang
Article
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Article
The modified radioimmunoassay of serum inhibin and its value in monitoring ovarian tumor
Objectives and Methods: A modified radioimmunoassay (RIA) of serum inhibin (INH) was developed and applied to measure serum INH contents in 39 fertile and 16 postmenopausal women. Thirty-three cases of ovarian...
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Article
αPIX nucleotide exchange factor is activated by interaction with phosphatidylinositol 3-kinase
p21-activated kinase (PAK) is a common effector protein of the small GTPases Cdc42 and Rac, leading to the activation of downstream mitogen activated protein kinases. PAK also mediates polarized cytoskeletal c...
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Article
Effect of anti-cardiac myosin antibody on prognosis of patients with acute myocardial infarction
To study whether there was an anti-cardiac myosin antibody (AMA) in serum of patients with myocardial infarction (AMI), relationship between AMA and the prognosis in patients with AMI was investigated. In 67 p...
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Detection of apoptotic cells and immunohistochemical study of bcl-2 and p53 gene protein in primary gastric mucosa-associated lymphoid tissue (MALT) lymphoma
Objective: To identify the apoptotic cells in gastric MALT lymphoma and its relationship between bcl-2 and p53 gene expression. Methods: TdT-mediated dUTP biotin Nick End labeling (TUNEL) and immuno-histochemi...
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Inactivation of farnesyltransferase and geranylgeranyltransferase I by caspase-3: Cleavage of the common α subunit during apoptosis
Caspase plays an important role in apoptosis. We report here that farnesyltransferase/geranylgeranyltransferase (FTase/GGTase)-α, a common subunit of FTase (α/βFTase) and GGTase I (α/βGGTase), was cleaved by casp...
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Article
Progesterone modulation of D5 receptor expression in hypothalamic ANP neurons, the role of estrogen
Aberrant responses to dopamine consequent to a reduction of D1-like receptors in critical regions of the brain have been implicated in schizophrenia.1 Whereas estrogen may protect against the onset and incidence ...
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Article
Clinical study on Rhubarb extract tablet in treating simple obesity
Objective: To study the clinical efficacy of **ghuang tablet (Rhubarb extract tablet, RET) in treating simple obesity.Methods: Four hundred and seventy-two simple obesity patients were randomly divided into 3 p...
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Article
The value of CT in differentiation of adrenal adenomas from malignant tumors
Objective: To evaluate the diagnostic efficacy of CT in differentiating adrenal adenomas from malignant tumors. Methods: 124 patients with 147 adrenal adenomas and malignant tumors were analyzed. Tumor size, m...
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Article
Major hepatic resection under total vascular exclusion
Objective: To eveluate major liver resections with vascular exclusion (TVE) in patients with hepatocellular carcinoma (HCC). Methods: Sixteen consecutive, major liver resections performed with TVE in HCC patie...
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Article
Inactivation of the CDKN2/pl6 gene induced by methylation at 5′-CpG Island and its relation to lung cancer
Objectives: To investigate the methylation status of the CDKN2/pl6 gene 5′-CpG island, and study the relationship between the CDKN2/pl6 gene inactivation by methylation and lung cancer. Methods: Genomic DNA ex...
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Article
Experimental study on AT1-receptor-peptide-induced myocardial immune damage in rat
In order to investigate the immunological damage in rat immunized with ATI-receptor peptide. 18 male Wistar rats were divided into two groups: immunized-group (n=12), each rat was immunized with 150 μg AT1-recept...
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Article
Chinese drugs that invigorate spleen to remove dampness and activate blood circulation to eliminate turbid for retarding progression of chronic renal failure
Objective: To investigate the effect of Chinese drugs (CD) that invigorate Spleen to remove Dampness and activate the blood circulation to eliminate Turbid for retarding progression of chronic renal failure (CRF)...
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Article
The study on intramyocardial calcium overload and apoptosis induced by cosackievirus B3
The isolated cardiac myocytes of rats were immediately infected by cosackievirus B3 (CVB3) to investigate the effects of such procedure on the cell cycle, apoptosis and intrazellular ionized calcium (Ca2+ i) of c...
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Article
Clinical observation on treatment of postpartum hemorrhage by xuesaitong soft capsule
To observe the effect of Xuesaitong (XST) soft capsule in treating postpartum hemorrhage.
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Article
Antitumor effect of BRM
Objective: To evaluate the antitumor effect of BRM, a Chinese traditional medical compound herb, and its mechanism. Methods: Tumor inhibition was tested in vivo on mice with subcutaneous transplanted tumor cells
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Article
Inducement of specific CTLs by antigen-peptides from human leukemia cells and their cytotoxicity to leukemia cells
To investigate the inducement of cytotoxic T lymphocytes (CTLs) by antigen peptides mixture from different leukemia cells and the cross-reaction of the mixtures from different cell lines, antigen peptides mixt...
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Article
MAD2-induced sensitization to vincristine is associated with mitotic arrest and Raf/Bcl-2 phosphorylation in nasopharyngeal carcinoma cells
Mitotic arrest deficient 2 (MAD2) is thought to be a key component of the mitotic checkpoint, which ensures accurate chromosome segregation. Reduced expression of MAD2 protein is associated with mitotic checkp...
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Article
Altered expression of the RON receptor tyrosine kinase in primary human colorectal adenocarcinomas: generation of different splicing RON variants and their oncogenic potential
The RON receptor tyrosine kinase is a member of the MET proto-oncogene family that has been implicated in regulating motile-invasive phenotypes in certain types of epithelial cancers. The purpose of this study...
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Article
Expression of phospho-β-catenin and its significance in non-small cell lung cancer
Objective: To investigate phospho-β-catenin expression in non-small cell lung cancer (NSCLC) and to study the relationship between phospho-β-catenin expression and some clinical pathological factors. Methods: ...
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Article
Effect of ligustrazine on activity changes of angiotensin II in plasma and cerebrospinal fluid in Patients with vascular dementia
Objective: To study the relationship between the activity changes of angiotensin II (Ang II) in plasma, cerebrospinal fluid (CSF) and the pathophysiology of vascular dementia (VD) on the one hand...
