Skip to main content

33 Result(s)

within Article Remove this filter Abba J Kastin Remove this filter

Page of 2 next disabled
and

  1. No Access

    Article

    Circulating TGF-β1 does not cross the intact blood-brain barrier

    Transforming growth factor-β (TGF-β) from the periphery can cross the disrupted blood-brain barrier (BBB) to exert neuroprotective effects on the brain. Here, we quantify its permeation across the normal mouse...

    Abba J. Kastin, Victoria Akerstrom, Weihong Pan in Journal of Molecular Neuroscience (2003)

  2. No Access

    Article

    Increased hippocampal uptake of tumor necrosis factor α and behavioral changes in mice

    Brain trauma may alter the function of the blood-brain barrier (BBB) and affect psychomotor activity. We have shown that the transport system for tumor necrosis factor α (TNFα) at the BBB undergoes regulatory ...

    Weihong Pan, Abba J. Kastin, Tova Rigai, Robert McLay… in Experimental Brain Research (2003)

  3. No Access

    Article

    Interactions of glucagon-like peptide-1 (GLP-1) with the blood-brain barrier

    Glucagon-like peptide-1 (GLP-1) reduces insulin requirement in diabetes mellitus and promotes satiety. GLP-1 in the periphery (outside the CNS) has been shown to act on the brain to reduce food ingestion. As G...

    Abba J. Kastin, Victoria Akerstrom, Weihong Pan in Journal of Molecular Neuroscience (2002)

  4. No Access

    Article

    Saturable brain-to-blood transport of endomorphins

    Opiate-modulating tetrapeptides such as tyrosine-melanocyte-stimulating hormone-release inhibiting factor-1 (Tyr-MIF-1; Tyr-Pro-Leu-Gly-NH2) and Tyr-W-MIF-1 (Tyr-Pro-Trp-Gly-NH2) are saturably transported from b...

    Abba J. Kastin, Melita B. Fasold, Rebecca R. Smith… in Experimental Brain Research (2001)

  5. No Access

    Article

    A potent and selective endogenous agonist for the µ-opiate receptor

    Peptides have been identified in mammalian brain that are considered to be endogenous agonists for the δ (enkephalins) and κ (dynorphins) opiate receptors, but none has been found to have any preference for th...

    James E. Zadina, Laszlo Hackler, Lin-Jun Ge, Abba J. Kastin in Nature (1997)

  6. No Access

    Article

    Delivering Peptides to the Central Nervous System: Dilemmas and Strategies

    Peptides have been shown to cross the blood–brain barrier (BBB) as intact molecules so that they can influence the central nervous system. Peptides cross by saturable and nonsaturable mechanisms in the directi...

    William A. Banks, Abba J. Kastin, Carlos M. Barrera in Pharmaceutical Research (1991)

  7. No Access

    Article

    Effect of neurotransmitters on the system that transports Tyr-MIF-1 and the enkephalins across the blood-brain barrier: a dominant role for serotonin

    Neurotransmitters and neuropeptides interact in several ways. We studied a new type of interaction: the effect of neurotransmitters on the saturable system that transports Tyr-MIF-1 and the enkephalins out of ...

    William A. Banks, Abba J. Kastin in Psychopharmacology (1989)

  8. No Access

    Article

    The aluminum-induced increase in blood-brain barrier permeability to delta-sleep-inducing peptide occurs throughout the brain and is independent of phosphorus and acetylcholinesterase levels

    The effect of aluminum on levels of inorganic phosphorus and acetylcholinesterase in blood and brain and on permeability of the blood-brain barrier (BBB) in different regions of the brain to the neuropeptide d...

    William A. Banks, Abba J. Kastin in Psychopharmacology (1985)

  9. Article

    The effects of neonatal injections of α-MSH on the open-field behavior of juvenile and adult rats

    Male and female infant albino rats, between the ages of 2 and 7 days, were treated with either MSH or the vehicle solution and then tested in an open-field apparatus when they were 45 days old and again when t...

    Bill E. Beckwith, R. Karen O’quin, Marilyn S. Petro… in Physiological Psychology (1977)

    Download PDF (1020 KB)

  10. No Access

    Article

    Psychopharmacological and endocrinological effects of melanocyte stimulating hormones in normal man

    A double blind crossover trial of the effects of synthetic alpha melanocyte stimulating hormone (alpha MSH) and synthetic beta melanocyte stimulating hormone (beta 1–22 MSH) on the contingent negative variatio...

    Heather Ashton, J. E. Millman, Rosemary Telford, J. W. Thompson… in Psychopharmacology (1977)

  11. Article

    Characterization of the Hormonal Responses to Luteinizing Hormone-Releasing Hormone (LH-RH) in Prepubertal and Adult Subjects

    Extract: Luteinizing hormone-releasing hormone (LH-RH), purified from porcine hypothalamic tissue, was administered in an intravenous dose of 300 $mUg to four prepubertal and four adult human subjects. The result...

    Abba J Kastin, Andrew V Schally, Don S Schalch, Stanley G Korenman… in Pediatric Research (1972)

    Download PDF (931 KB)

  12. No Access

    Article

    Autoregulation of Release of Melanocyte Stimulating Hormone from the Rat Pituitary

    MELANOCYTE stimulating hormone (MSH) enables amphibians such as the frog to change skin colour and thereby adapt to the environment. The function of this pituitary hormone in mammals such as the albino rat has...

    ABBA J. KASTIN, ANDREW V. SCHALLY in Nature (1967)

  13. No Access

    Article

    Melanocyte-stimulating Hormone Activity of Synthetic MSH and ACTH Peptides, in vivo and in vitro

    SIMULTANEOUSLY performed in vivo and in vitro determinations of the melanocyte-stimulating hormone (MSH) activity of a large number of synthetic MSH and ACTH peptides have not been reported previously. The work r...

    ABBA J. KASTIN, ANDREW V. SCHALLY, HARUAKI YAJIMA, KAZUO KUBO in Nature (1965)

Page of 2 next disabled