3,867 Result(s)
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Open AccessCorrection: Systematic review of fatigue severity in ME/CFS patients: insights from randomized controlled trials
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Open AccessAuthor Correction: Development of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers
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Open AccessCorrection: H3.3-G34W in giant cell tumor of bone functionally aligns with the exon choice repressor hnRNPA1L2
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Open AccessChemotherapy-related cardiotoxicity and its symptoms in patients with breast cancer: a sco** review
Chemotherapy-related cardiotoxicity is a significant concern because it is a major cause of morbidity. This study aimed to provide in-depth information on the symptoms of chemotherapy-related cardiotoxicity (C...
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Spiking neural networks for physiological and speech signals: a review
The integration of Spiking Neural Networks (SNNs) into the analysis and interpretation of physiological and speech signals has emerged as a groundbreaking approach, offering enhanced performance and deeper ins...
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Highly efficient and specific regulation of gene expression using enhanced CRISPR-Cas12f system
The recently developed CRISPR activator (CRISPRa) system uses a CRISPR-Cas effector-based transcriptional activator to effectively control the expression of target genes without causing DNA damage. However, ex...
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In vivo AAV–SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy
Natural killer (NK) cells have clinical potential against cancer; however, multiple limitations hinder the success of NK cell therapy. Here, we performed unbiased functional map** of tumor-infiltrating NK (T...
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Open AccessAuthor Correction: Inhibition of lysine acetyltransferase KAT6 in ER+HER2− metastatic breast cancer: a phase 1 trial
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Synthesis, Invitro Cytotoxic Activity and Optical Analysis of Substituted Schiff Base Derivatives
Fluorescent cytotoxic compounds with readout delivery are crucial in chemotherapy. The growing demands of these treatment strategies require the novel heterocyclic molecules with better selectivity alongside f...
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Advancements of hot-melt extrusion technology to address unmet patient needs and pharmaceutical quality aspects
Hot-melt extrusion (HME) significantly affects pharmaceutical manufacturing by enhancing drug solubility and bioavailability. Advancements in HME technology to produce FDA-approved drugs have highlighted its r...
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Author Correction: A shifting role of thalamocortical connectivity in the emergence of cortical functional organization
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Open AccessTranscriptome analysis of cynomolgus macaques throughout their lifespan reveals age-related immune patterns
Despite the different perspectives by diverse research sectors spanning several decades, aging research remains uncharted territory for human beings. Therefore, we investigated the transcriptomic characteristi...
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Open AccessAssociation between exercise habits and incident type 2 diabetes mellitus in patients with thyroid cancer: nationwide population-based study
We investigated the association between exercise habits before or after thyroidectomy and incident type 2 diabetes mellitus (T2DM) in patients with thyroid cancer.
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Open AccessRole of SYT11 in human pan-cancer using comprehensive approaches
Synaptotagmin 11 (SYT11) plays a pivotal role in neuronal vesicular trafficking and exocytosis. However, no independent prognostic studies have focused on various cancers. In this study, we aimed to summarize ...
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Enhancing pediatric access to cell and gene therapies
Increasing numbers of cell and gene therapies (CGTs) are emerging to treat and cure pediatric diseases. However, small market sizes limit the potential return on investment within the traditional biopharmaceut...
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Correction: Recent progress in DNA data storage based on high-throughput DNA synthesis
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Open AccessDevelopment of an anti-tauopathy mucosal vaccine specifically targeting pathologic conformers
Alzheimer’s disease (AD) and related tauopathies are associated with pathological tau protein aggregation, which plays an important role in neurofibrillary degeneration and dementia. Targeted immunotherapy to ...
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Review on spiking neural network-based ECG classification methods for low-power environments
This paper reviews arrhythmia classification studies using electrocardiogram (ECG) signals. Research on automatically diagnosing arrhythmia in daily life has been actively underway for early detection and trea...
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Macrophage membrane coated discoidal polymeric particles for evading phagocytosis
The purpose of this study was to investigate the potential of discoidal polymeric particles (DPPs) coated with macrophage membranes as a novel drug delivery system. The study aimed to determine whether these c...
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Open AccessThe identification of effective tumor-suppressing neoantigens using a tumor-reactive TIL TCR-pMHC ternary complex
Neoantigens are ideal targets for cancer immunotherapy because they are expressed de novo in tumor tissue but not in healthy tissue and are therefore recognized as foreign by the immune system. Advances in nex...
