576 Result(s)

Article

Negative regulation of UCP2 by TGFβ signaling characterizes low and intermediate-grade primary breast cancer

The histological manifestation of growth-regulating and differentiation-inducing signals in cancer cells is considered as a key component for clinical outcome prediction and commonly defined as tumor different...

A Sayeed, Z Meng, G Luciani, L-C Chen, J L Bennington, S H Dairkee in Cell Death & Disease (2010)

Article

The X-linked mental retardation gene PHF8 is a histone demethylase involved in neuronal differentiation

Recent studies have identified mutations in PHF8, an X-linked gene encoding a JmjC domain-containing protein, as a causal factor for X-linked mental retardation (XLMR) and cleft lip/cleft palate. However, the ...

Jihui Qiu, Guang Shi, Yuanhui Jia, **g Li, Meng Wu, Jiwen Li, Shuo Dong… in Cell Research (2010)

Article

Multi-walled carbon nanotubes conjugated to tumor protein enhance the uptake of tumor antigens by human dendritic cells in vitro

Zhao Sun, Wei Wang, Jie Meng, Shuchang Chen, Haiyan Xu, **an-Da Yang in Cell Research (2010)

Article

Spontaneously immortalised bovine mammary epithelial cells exhibit a distinct gene expression pattern from the breast cancer cells

Spontaneous immortalisation of cultured mammary epithelial cells (MECs) is an extremely rare event, and the molecular mechanism behind spontaneous immortalisation of MECs is unclear. Here, we report the establ...

Chenfu Zhao, Lu Meng, Hongyu Hu, Xudong Wang, Fangyu Shi, Yajuan Wang… in BMC Cell Biology (2010)

Article

A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum

A natural BH3-mimetic, small-molecule inhibitor of Bcl-2, (−)-gossypol, shows promise in ongoing phase II and III clinical trials for human prostate cancer. In this study we show that (−)-gossypol preferential...

J Lian, X Wu, F He, D Karnak, W Tang, Y Meng, D **ang, M Ji… in Cell Death & Differentiation (2011)

Article

Direct differentiation of atrial and ventricular myocytes from human embryonic stem cells by alternating retinoid signals

Although myocyte cell transplantation studies have suggested a promising therapeutic potential for myocardial infarction, a major obstacle to the development of clinical therapies for myocardial repair is the ...

Qiangzhe Zhang, Junjie Jiang, Pengcheng Han, Qi Yuan, **g Zhang… in Cell Research (2011)

Article

Isolation and Phylogenetic Analysis of H1N1 Swine Influenza Virus from Sick Pigs in Southern China

Two swine influenza (SI) H1N1 virus was isolated from a pig during a severe outbreak of respiratory disease in south China. The two H1N1 influenza viruses were classical SI virus. A/swine/Guangdong/L6/09 is cl...

Wei-li Kong, Yu-mao Huang, Nan Cao, Hai-tao Qi… in Indian Journal of Virology (2011)

Article

Determining intracellular temperature at single-cell level by a novel thermocouple method

Changling Wang, Ruizhi Xu, Wenjuan Tian, **aoli Jiang, Zhengyu Cui… in Cell Research (2011)

Article

Erratum: Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

Correction to: Cell Research (2012) 22:107–126. doi:10.1038/cr.2011.158; published online 20 September 2011 In the initial published version of this article, an error was made during the assembly of Figure 5B....

Lin Zhang, Dongxia Hou, ** Chen, Donghai Li, Lingyun Zhu, Yu**g Zhang… in Cell Research (2012)

Article

Identification and expansion of cancer stem cells in tumor tissues and peripheral blood derived from gastric adenocarcinoma patients

Gastric cancer is the fourth most common cancer worldwide, with a high rate of death and low 5-year survival rate. To date, there is a lack of efficient therapeutic protocols for gastric cancer. Recent studies...

Tie Chen, Kun Yang, Jianhua Yu, Wentong Meng, Dandan Yuan, Feng Bi… in Cell Research (2012)

Article

Exogenous plant MIR168a specifically targets mammalian LDLRAP1: evidence of cross-kingdom regulation by microRNA

Our previous studies have demonstrated that stable microRNAs (miRNAs) in mammalian serum and plasma are actively secreted from tissues and cells and can serve as a novel class of biomarkers for diseases, and a...

Lin Zhang, Dongxia Hou, ** Chen, Donghai Li, Lingyun Zhu, Yu**g Zhang… in Cell Research (2012)

Article

Induction of fibroblasts to neurons through adenoviral gene delivery

Fengxi Meng, Siye Chen, Qinglong Miao, Kechun Zhou, Qicheng Lao… in Cell Research (2012)

Article

Onconase downregulates microRNA expression through targeting microRNA precursors

Meng Qiao, Li-Dong Zu, **ao-Hong He, Ru-Ling Shen, Qing-Cheng Wang… in Cell Research (2012)

Article

Phosphatidylserine exposure during apoptosis reflects bidirectional trafficking between plasma membrane and cytoplasm

Phosphatidylserine (PS) exposure on the external leaflet of the plasma membrane is widely observed during apoptosis and forms the basis for the annexin V binding assay to detect apoptotic cell death. Current e...

S-H Lee, X W Meng, K S Flatten, D A Loegering, S H Kaufmann in Cell Death & Differentiation (2013)

Article

Nitric oxide suppresses NLRP3 inflammasome activation and protects against LPS-induced septic shock

Inflammasomes are multi-protein complexes that trigger the activation of caspase-1 and the maturation of interleukin-1β (IL-1β), yet the regulation of these complexes remains poorly characterized. Here we show...

Kairui Mao, Shuzhen Chen, Mingkuan Chen, Yonglei Ma, Yan Wang, Bo Huang… in Cell Research (2013)

Article

Rapid and efficient reprogramming of human fetal and adult blood CD34⁺ cells into mesenchymal stem cells with a single factor

The direct conversion of skin cells into somatic stem cells has opened new therapeutic possibilities in regenerative medicine. Here, we show that human induced mesenchymal stem cells (iMSCs) can be efficiently...

**anmei Meng, Rui-Jun Su, David J Baylink, Amanda Neises, Jason B Kiroyan… in Cell Research (2013)

Article

Brown adipose tissue transplantation improves whole-body energy metabolism

**aomeng Liu, Zongji Zheng, **aoming Zhu, Minghui Meng, Lan Li… in Cell Research (2013)

Article

Biofilm from a clinical strain of Cryptococcus neoformans activates the NLRP3 inflammasome

Guowei Lei, Mingkuan Chen, Hua Li, Jun-Ling Niu, Shuxian Wu, Liming Mao… in Cell Research (2013)

Article

ER stress-mediated apoptosis induced by celastrol in cancer cells and important role of glycogen synthase kinase-3β in the signal network

HeLa cells treated with celastrol, a natural compound with inhibitive effect on proteasome, exhibited increase in apoptotic rate and characteristics of apoptosis. To clarify the signal network activated by cel...

L Feng, D Zhang, C Fan, C Ma, W Yang, Y Meng, W Wu, S Guan, B Jiang… in Cell Death & Disease (2013)

Article

Autophagy prevents irradiation injury and maintains stemness through decreasing ROS generation in mesenchymal stem cells

Stem cells were characterized by their stemness: self-renewal and pluripotency. Mesenchymal stem cells (MSCs) are a unique type of adult stem cells that have been proven to be involved in tissue repair, immuno...

J Hou, Z-p Han, Y-y **g, X Yang, S-s Zhang, K Sun, C Hao, Y Meng… in Cell Death & Disease (2013)