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  1. Article

    Open Access

    Population-based BRCA germline mutation screening in the Han Chinese identifies individuals at risk of BRCA mutation-related cancer: experience from a clinical diagnostic center from greater Shanghai area

    Deleterious BRCA1/2 (BRCA) mutation raises the risk for BRCA mutation-related malignancies, including breast, ovarian, prostate, and pancreatic cancer. Germline variation of BRCA exhibits substantial ethnical div...

    Zhiyuan Wu, Qingyun Zhang, Yiting **, **nju Zhang, Yanli Chen, Can Yang in BMC Cancer (2024)

  2. No Access

    Article

    Comparison of the predictive values of MRI-based vertebral bone quality scores for the determination of osteoporosis in different diseases

    The study aimed to examine the consistency of vertebral bone quality (VBQ) scores for assessing osteoporosis across different etiologies and explore the predictive value of various VBQ scores for fragility ver...

    Lu Wang, Qian Deng, Bang Wang, **ng-Bin Li, Zhi-Jun Sha in European Spine Journal (2024)

  3. No Access

    Article

    Tricarboxylic acid cycle metabolites: new players in macrophage

    Metabolic remodeling is a key feature of macrophage activation and polarization. Recent studies have demonstrated the role of tricarboxylic acid (TCA) cycle metabolites in the innate immune system. In the curr...

    Ying Yang, Bing-Bing Cui, Jian Li, Jiao-Jiao Shan, Jun Xu in Inflammation Research (2024)

  4. No Access

    Article

    AGV indoor localization: a high fidelity positioning and map building solution based on drawstring displacement sensors

    The rapid evolution of artificial intelligence (AI) and robotics technologies are bringing drastic changes to society and industry in these recent years. The impressive progress in facilitating smart manufactu...

    Shih-Yuan Wang, Che-Ming Li, Sze-Teng Liong in Journal of Ambient Intelligence and Humani… (2024)

  5. Article

    Open Access

    A prospective phase II clinical trial of total neoadjuvant therapy for locally advanced gastric cancer and gastroesophageal junction adenocarcinoma

    To investigate the safety and efficacy of the neoadjuvant chemoradiotherapy (NCRT) followed by neoadjuvant consolidation chemotherapy (NCCT) and surgery for locally advanced gastric cancer (GC) or gastroesopha...

    **-Ming Shi, Ning Li, Li-Ming Jiang, Lin Yang, Shu-Lian Wang in Scientific Reports (2024)

  6. Article

    Open Access

    Tailoring d-band center of high-valent metal-oxo species for pollutant removal via complete polymerization

    Polymerization-driven removal of pollutants in advanced oxidation processes (AOPs) offers a sustainable way for the simultaneous achievement of contamination abatement and resource recovery, supporting a low-c...

    Hong-Zhi Liu, **ao-Xuan Shu, Mingjie Huang, Bing-Bing Wu in Nature Communications (2024)

  7. Article

    Open Access

    Multi-modal molecular determinants of clinically relevant osteoporosis subtypes

    Due to a rapidly aging global population, osteoporosis and the associated risk of bone fractures have become a wide-spread public health problem. However, osteoporosis is very heterogeneous, and the existing s...

    Chunchun Yuan, **ang-Tian Yu, **g Wang, Bing Shu, **ao-Yun Wang in Cell Discovery (2024)

  8. No Access

    Article

    Investigating the Loess Plateau’s coevolution of precipitation and natural vegetation cover

    The Chinese government’s program of reverting agriculture to forests and grasslands has largely been responsible for the phenomenon of the Loess Plateau becoming green, which has attracted the attention of the...

    Shu-qi Zhang, Yu-wei Wang, Hong-bo Zhang, Feng-guang Lyu in Environmental Earth Sciences (2024)

  9. Article

    Open Access

    Association of dietary live microbe intake with various cognitive domains in US adults aged 60 years or older

    The purpose of this study was to explore whether dietary live microbe intake is associated with various cognitive domains using data from the National Health and Nutrition Examination Survey (NHANES) from 2011...

    Jia-jie Lv, **n-yu Li, **g-bing Wang, **-tao Yang, Min-yi Yin in Scientific Reports (2024)

  10. No Access

    Article

    Comparing robotic and open surgical techniques in gallbladder cancer management: a detailed systematic review and meta-analysis

    This meta-analysis aims to evaluate the safety and oncological outcomes of robotic surgery compared to open surgery in treating gallbladder cancer (GBC). In October 2023, we performed a literature search acros...

    Jie Wang, Zhao Li, Lin-Lin Chen, **g-Bing Zhao, Jian-Lin Wu in Journal of Robotic Surgery (2024)

  11. Article

    Open Access

    Genome-wide identification of GA2ox genes family and analysis of PbrGA2ox1-mediated enhanced chlorophyll accumulation by promoting chloroplast development in pear

    Chlorophyll (Chl) is an agronomic trait associated with photosynthesis and yield. Gibberellin 2-oxidases (GA2oxs) have previously been shown to be involved in Chl accumulation. However, whether and how the Pbr...

    Guoling Guo, Lun Liu, Tai**g Shen, Haozhe Wang, Shuqin Zhang, Yu Sun in BMC Plant Biology (2024)

  12. No Access

    Article

    Phenethyl isothiocyanate inhibits metastasis potential of non-small cell lung cancer cells through FTO mediated TLE1 m6A modification

    N6-methyladenosine (m6A) modification is a prevalent RNA epigenetic modification, which plays a crucial role in tumor progression including metastasis. Isothiocyanates (ITCs) are natural compounds and inhibit the...

    Qi-cheng Zhang, Yong-mei Qian, Ying-hui Ren, Meng-meng Chen in Acta Pharmacologica Sinica (2024)

  13. No Access

    Article

    ZIF-8-functionalized polymer electrolyte with enhanced performance for high-temperature solid-state lithium metal batteries

    Solid polymer electrolytes (SPEs) with high ionic conductivity are desirable for solid-state lithium metal batteries (SSLMBs) to achieve enhanced safety and energy density. Incorporating nanofillers into a pol...

    **-Fang Zhang, Yuan-Yuan Wang, **ao-Feng Li, Gen-Yan Zhang, Ying Li in Rare Metals (2024)

  14. No Access

    Article

    Research on the knee region of cosmic ray by using a novel type of electron–neutron detector array

    By accurately measuring composition and energy spectrum of cosmic ray, the origin problem of so called “knee” region (energy >one PeV) can be solved. However, up to the present, the results of the spectrum in ...

    Bing-Bing Li, **n-Hua Ma, Shu-Wang Cui, Hao-Kun Chen, Tian-Lu Chen in Frontiers of Physics (2024)

  15. Article

    Open Access

    Addendum: Cellular differentiation into hyphae and spores in halophilic archaea

    Shu-Kun Tang, **ao-Yang Zhi, Yao Zhang, Kira S. Makarova in Nature Communications (2024)

  16. No Access

    Article

    Structures and diversities of bacterial communities in oil-contaminated soil at shale gas well site assessed by high-throughput sequencing

    Currently, there is limited understanding of the structures and variabilities of bacterial communities in oil-contaminated soil within shale gas development. The Changning shale gas well site in Sichuan provin...

    Hongyang Ren, Yuanpeng Deng, Dan Zhao in Environmental Science and Pollution Resear… (2024)

  17. Article

    Open Access

    Multi-omics and Multi-VOIs to predict esophageal fistula in esophageal cancer patients treated with radiotherapy

    This study aimed to develop a prediction model for esophageal fistula (EF) in esophageal cancer (EC) patients treated with intensity-modulated radiation therapy (IMRT), by integrating multi-omics features from...

    Wei Guo, Bing Li, Wencai Xu, Chen Cheng in Journal of Cancer Research and Clinical On… (2024)

  18. No Access

    Article

    Human microbiota from drug-naive patients with obsessive-compulsive disorder drives behavioral symptoms and neuroinflammation via succinic acid in mice

    Emerging evidence suggests that the gut microbiota is closely related to psychiatric disorders. However, little is known about the role of the gut microbiota in the development of obsessive-compulsive disorder...

    Ying-Dan Zhang, Dong-Dong Shi, Bing-Bing Liao, Yi Li, Sen Zhang in Molecular Psychiatry (2024)

  19. Article

    Open Access

    A compact multi-pixel superconducting nanowire single-photon detector array supporting gigabit space-to-ground communications

    Classical and quantum space-to-ground communications necessitate highly sensitive receivers capable of extracting information from modulated photons to extend the communication distance from near-earth orbits ...

    Hao Hao, Qing-Yuan Zhao, Yang-Hui Huang, Jie Deng in Light: Science & Applications (2024)

  20. Article

    Open Access

    In vivo assembly enhanced binding effect augments tumor specific ferroptosis therapy

    Emerging evidence indicates that the activation of ferroptosis by glutathione peroxidase 4 (GPX4) inhibitors may be a prominent therapeutic strategy for tumor suppression. However, the wide application of GPX4...

    Da-Yong Hou, Dong-Bing Cheng, Ni-Yuan Zhang, Zhi-Jia Wang in Nature Communications (2024)

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