285 Result(s)
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Article
**an-Sheng Jia
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Stability control of deep-buried roadways using large deformation and increasing resistance anchor cables
A new large deformation and increasing resistance anchor cable was developed. The energy absorption and pressure release were achieved through connecting six straight tube-shaped steel structures (thickness of...
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Open AccessBiogeographic patterns of meio- and micro-eukaryotic communities in dam-induced river-reservoir systems
Although the Three Gorges Dam (TGD) is the world’s largest hydroelectric dam, little is known about the spatial–temporal patterns and community assembly mechanisms of meio- and micro-eukaryotes and its two sub...
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Ferroelectric transistors based on shear-transformation-mediated rhombohedral-stacked molybdenum disulfide
To develop low-power, non-volatile computing-in-memory device using ferroelectric transistor technologies, ferroelectric channel materials with scaled thicknesses are required. Two-dimensional semiconductors, ...
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Open AccessAdvances in nuclear detection and readout techniques
“A Craftsman Must Sharpen His Tools to Do His Job,” said Confucius. Nuclear detection and readout techniques are the foundation of particle physics, nuclear physics, and particle astrophysics to reveal the nat...
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ASPECTS-based net water uptake outperforms target mismatch for outcome prediction in patients with acute ischemic stroke and late therapeutic window
To compare the prognostic value of net water uptake (NWU) and target mismatch (TM) on CT perfusion (CTP) in acute ischemic stroke (AIS) patients with late time window.
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CDK6 is a novel predictive and prognosis biomarker correlated with immune infiltrates in multiple human neoplasms, including small cell lung carcinoma
The roles of cyclin-dependent kinase 6 (CDK6) in various cancers, including small cell lung carcinoma (SCLC), remain unclear. Here, 111,54 multi-center samples were investigated to determine the expression, clini...
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CD7 targeted “off-the-shelf” CAR-T demonstrates robust in vivo expansion and high efficacy in the treatment of patients with relapsed and refractory T cell malignancies
T-cell acute lymphoblastic leukemia (T-ALL) represents an area of highly unmet medical needs. Once relapsed, patients have limited treatment options and poor prognosis. T-ALL antigens such as CD7 is extensivel...
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Microstructure evolution of 7050 Al alloy fasteners during cold upsetting after equal channel angular pressing
The innovative combination of equal channel angular pressing (ECAP) and cold upsetting (CU) is significant for producing high-strength Al alloy fasteners with ultrafine grains. However, the relationship betwee...
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Open AccessHSPA8 acts as an amyloidase to suppress necroptosis by inhibiting and reversing functional amyloid formation
Ultra-stable fibrous structure is a hallmark of amyloids. In contrast to canonical disease-related amyloids, emerging research indicates that a significant number of cellular amyloids, termed ‘functional amylo...
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A multi-scale mixed convolutional network for infrared image super-resolution reconstruction
Infrared image is widely used in military, medical, monitoring security and other fields. Due to the limitation of hardware devices, infrared image has the problems of low signal-to-noise ratio, blurred edge a...
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Open AccessThe liver microenvironment orchestrates FGL1-mediated immune escape and progression of metastatic colorectal cancer
Colorectal cancer (CRC) patients with liver metastases usually obtain less benefit from immunotherapy, and the underlying mechanisms remain understudied. Here, we identify that fibrinogen-like protein 1 (FGL1)...
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ITGB4 Serves as an Identification and Prognosis Marker Associated with Immune Infiltration in Small Cell Lung Carcinoma
Integrin beta 4 (ITGB4) is a vital factor for numerous cancers. However, no reports regarding ITGB4 in small cell lung carcinoma (SCLC) have been found in the existing literature. This study systematically invest...
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Chemical Recycling of Poly(ethylene furanoate) into Value-added Poly(ethylene-co)-isosorbide furanoate)
We present here a novel strategy for the chemical recycling of bio-based poly(ethylene furanoate)s (PEF) to value-added high-performance bio-based poly(ethylene-co-isosorbide furanoate) (PEIF) copolyesters by the...
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Open AccessHyodeoxycholic acid ameliorates nonalcoholic fatty liver disease by inhibiting RAN-mediated PPARα nucleus-cytoplasm shuttling
Nonalcoholic fatty liver disease (NAFLD) is usually characterized with disrupted bile acid (BA) homeostasis. However, the exact role of certain BA in NAFLD is poorly understood. Here we show levels of serum hy...
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Open AccessHigh-density lipoprotein regulates angiogenesis by long non-coding RNA HDRACA
Normal high-density lipoprotein (nHDL) can induce angiogenesis in healthy individuals. However, HDL from patients with coronary artery disease undergoes various modifications, becomes dysfunctional (dHDL), and...
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Open AccessCamrelizumab combined with apatinib in patients with first-line platinum-resistant or PD-1 inhibitor resistant recurrent/metastatic nasopharyngeal carcinoma: a single-arm, phase 2 trial
Immunotherapy combined with antiangiogenic targeted therapy has improved the treatment of certain solid tumors, but effective regimens remain elusive for refractory recurrent/metastatic nasopharyngeal carcinom...
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Open AccessInfection of sheep by Echinococcus multilocularis in Gansu, China: evidence from mitochondrial and nuclear DNA analysis
In the normal life cycle of the parasite (Echinococcus multilocularis) that causes alveolar echinococcosis, domestic and wild carnivores act as definitive hosts, and rodents act as intermediate hosts. The present...
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Comparison of haploidentical–allogeneic hematopoietic stem cell transplantation and intensive immunosuppressive therapy for patients with severe aplastic anemia with an absolute neutrophil count of zero: a retrospective study
A retrospective analysis was conducted based on the clinical data from 60 patients older than 16 years from January 2016 to January 2021. All the patients were newly diagnosed with severe aplastic anemia (SAA)...
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Specific pupylation as IDEntity reporter (SPIDER) for the identification of protein-biomolecule interactions
Protein-biomolecule interactions play pivotal roles in almost all biological processes. For a biomolecule of interest, the identification of the interacting protein(s) is essential. For this need, although man...
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A New Bothriolepid Antiarch from the Middle Devonian in Luquan, Yunnan, South China and Its Stratigraphic and Biogeographic Significances
Chahuaqingolepis magniporus gen. et sp. nov., a new taxon of Bothriolepididae (Placoder-mi: Antiarcha), is described from the Middle Devonian in Luquan County, Yunnan Province, South China. The phylogenetic analy...
