48 Result(s)
within
English
Science, multidisciplinary
**-peng Pei
Article
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Article
Open AccessDietary magnesium deficiency impaired intestinal structural integrity in grass carp (Ctenopharyngodon idella)
Grass carp (223.85–757.33 g) were fed diets supplemented with magnesium (73.54–1054.53 mg/kg) for 60 days to explore the impacts of magnesium deficiency on the growth and intestinal structural integrity of the...
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Open AccessSpatial-temporal dynamics of carbon emissions and carbon sinks in economically developed areas of China: a case study of Guangdong Province
This study analysed spatial-temporal dynamics of carbon emissions and carbon sinks in Guangdong Province, South China. The methodology was based on land use/land cover data interpreted from continuous high-res...
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Nuclear cGAS suppresses DNA repair and promotes tumorigenesis
Accurate repair of DNA double-stranded breaks by homologous recombination preserves genome integrity and inhibits tumorigenesis. Cyclic GMP–AMP synthase (cGAS) is a cytosolic DNA sensor that activates innate i...
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Open AccessThe p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer
The biological role of miR-500a-5p has not yet been reported in the context of colorectal cancer (CRC). Here, we show that miR-500a-5p expression is decreased in CRC tissues compared with adjacent normal tissu...
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Open AccessPlasma Aβ42 and Total Tau Predict Cognitive Decline in Amnestic Mild Cognitive Impairment
Levels of amyloid-β (Aβ) and tau peptides in brain have been associated with Alzheimer disease (AD). The current study investigated the abilities of plasma Aβ42 and total-tau (t-tau) levels in predicting cogni...
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Open AccessInitial radiographic tracheal ratio in predicting clinical outcomes in croup in children
Croup is the leading infectious disease resulting in pediatric upper airway obstruction. Our purpose is to analyze diverse features of neck radiographs could be seen as an objective tool to predict outcomes in...
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Open AccessRelative posture between head and finger determines perceived tactile direction of motion
The hand explores the environment for obtaining tactile information that can be fruitfully integrated with other functions, such as vision, audition, and movement. In theory, somatosensory signals gathered by ...
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Open AccessEnd-to-end vascular anastomosis using a novel magnetic compression device in rabbits: a preliminary study
Magnetic compression anastomosis (MCA) has been appreciated as an innovative alternative to manual suturing in vascular reconstruction. However, magnetic devices have limitations in their applications. The pre...
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Open AccessAuthor Correction: Relative posture between head and finger determines perceived tactile direction of motion
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessPurification of HCC-specific extracellular vesicles on nanosubstrates for early HCC detection by digital scoring
We report a covalent chemistry-based hepatocellular carcinoma (HCC)-specific extracellular vesicle (EV) purification system for early detection of HCC by performing digital scoring on the purified EVs. Earlier...
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Open AccessAuthor Correction: End-to-end vascular anastomosis using a novel magnetic compression device in rabbits: a preliminary study
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Open AccessCharacterization of the genomic landscape and actionable mutations in Chinese breast cancers by clinical sequencing
The remarkable advances in next-generation sequencing technology have enabled the wide usage of sequencing as a clinical tool. To promote the advance of precision oncology for breast cancer in China, here we r...
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Open AccessIntegrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)
USP7, which encodes a deubiquitylating enzyme, is among the most frequently mutated genes in pediatric T-ALL, with somatic heterozygous loss-of-function mutations (haploinsufficiency) predominantly affecting the ...
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Open AccessEradicating mesothelin-positive human gastric and pancreatic tumors in xenograft models with optimized anti-mesothelin antibody–drug conjugates from synthetic antibody libraries
Mesothelin (MSLN) is an attractive candidate of targeted therapy for several cancers, and hence there are increasing needs to develop MSLN-targeting strategies for cancer therapeutics. Antibody–drug conjugates...
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Open AccessVisualizing designer quantum states in stable macrocycle quantum corrals
Creating atomically precise quantum architectures with high digital fidelity and desired quantum states is an important goal in a new era of quantum technology. The strategy of creating these quantum nanostruc...
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Open AccessTransgenic refractory Aedes aegypti lines are resistant to multiple serotypes of dengue virus
The areas where dengue virus (DENV) is endemic have expanded rapidly, driven in part by the global spread of Aedes species, which act as disease vectors. DENV replicates in the mosquito midgut and is disseminated...
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Open AccessAuthor Correction: Transgenic refractory Aedes aegypti lines are resistant to multiple serotypes of dengue virus
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Open AccessMemory B cell repertoire from triple vaccinees against diverse SARS-CoV-2 variants
Omicron (B.1.1.529), the most heavily mutated SARS-CoV-2 variant so far, is highly resistant to neutralizing antibodies, raising concerns about the effectiveness of antibody therapies and vaccines1,2. Here we exa...
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Open AccessThe burden and trend of gastric cancer and possible risk factors in five Asian countries from 1990 to 2019
The burdens and trends of gastric cancer are poorly understood, especially in high-prevalence countries. Based on the Global Burden of Disease Study 2019, we analyzed the incidence, death, and possible risk fa...
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Open AccessAntibody CDR amino acids underlying the functionality of antibody repertoires in recognizing diverse protein antigens
Antibodies recognize protein antigens with exquisite specificity in a complex aqueous environment, where interfacial waters are an integral part of the antibody–protein complex interfaces. In this work, we elu...
