46 Result(s)
within
Neurology
Psychiatry
**-li Lu
Article
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Article
Open AccessAn integrative analysis of genome-wide association study and regulatory SNP annotation datasets identified candidate genes for bipolar disorder
Bipolar disorder (BD) is a complex mood disorder. The genetic mechanism of BD remains largely unknown.
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Clinical significance of common-stem lenticulostriate arteries in patients with internal watershed infarction
A common-stem origin of lenticulostriate arteries (CS-LSAs) is an anatomical variation that supplies a moderate to large section of the basal ganglia. We hypothesized that CS-LSAs with a patent orifice are loc...
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Time Effects on Resting EEG in Children With/Without AD/HD
In this study we extend on behavioural evidence to examine the effect of time on EEG measures related to arousal and emotion/motivation in children with/without AD/HD. Thirty children with AD/HD and 30 age- an...
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Open AccessInherited and multiple de novo mutations in autism/developmental delay risk genes suggest a multifactorial model
We previously performed targeted sequencing of autism risk genes in probands from the Autism Clinical and Genetic Resources in China (ACGC) (phase I). Here, we expand this analysis to a larger cohort of patien...
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Open AccessResveratrol ameliorates prenatal progestin exposure-induced autism-like behavior through ERβ activation
Recent literatures indicate that maternal hormone exposure is a risk factor for autism spectrum disorder (ASD). We hypothesize that prenatal progestin exposure may counteract the neuroprotective effect of estr...
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The predictive accuracy of the black hole sign and the spot sign for hematoma expansion in patients with spontaneous intracerebral hemorrhage
In patients with spontaneous intracerebral hemorrhage (sICH), hematoma expansion (HE) is associated with poor outcome. Spot sign and black hole sign are neuroimaging predictors for HE. This study was aimed to ...
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Open AccessPrior Visual Experience Modulates Learning of Sound Localization Among Blind Individuals
Cross-modal learning requires the use of information from different sensory modalities. This study investigated how the prior visual experience of late blind individuals could modulate neural processes associa...
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The SG13S114 polymorphism of the ALOX5AP gene is associated with ischemic stroke in Europeans: a meta-analysis of 8062 subjects
The association between ALOX5AP SG13S114 polymorphism and ischemic stroke (IS) susceptibility has extensively been investigated, especially in white populations; however, the results were inconclusive. Here, w...
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Genetic association study between RIT2 and Parkinson’s disease in a Han Chinese population
Recent several meta-analyses and certain case–control studies suggested that the Ras-like without CAAX 2 (RIT2) rs12456492 increased the risk of Parkinson’s disease (PD) in Asian and Caucasian populations. Howeve...
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Prevalence of small intestinal bacterial overgrowth in Chinese patients with Parkinson’s disease
Parkinson’s disease (PD) is associated with gastrointestinal motility abnormalities that could favor the occurrence of small intestinal bacterial overgrowth (SIBO). The aim of the study was to assess the preva...
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Rapidly progressive neurological deterioration in anti-AMPA receptor encephalitis with additional CRMP5 antibodies
Anti-α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPAR) encephalitis positive for additional onconeural antibodies is rarely reported. Here we report the clinical features of a patient who d...
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Association of three candidate genetic variants in RAB7L1/NUCKS1, MCCC1 and STK39 with sporadic Parkinson’s disease in Han Chinese
Previous studies identified that polymorphisms RAB7L1/NUCKS1 rs823118, MCCC1 rs12637471 and STK39 rs1955337 to be the risk loci for Parkinson’s disease (PD) in a Caucasian population. However, the characteristics...
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Expression of interleukin-9 and its upstream stimulating factors in rats with ischemic stroke
To investigate the temporal expressions of IL-9 and its related cytokines after middle cerebral artery occlusion in rats. IL-9 and its related cytokines in ischemia brain and blood were tested after rats were ...
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Identifying the role of microRNAs in spinal cord injury
Spinal cord injury (SCI) is medically and socioeconomically debilitating, and effective treatments are lacking. The elucidation of the pathophysiological mechanisms underlying SCI is essential for develo** e...
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Connections between EM2- and SP-containing terminals and GABAergic neurons in the mouse spinal dorsal horn
Endomorphin-2 (EM2) demonstrates a potent antinociceptive effect in pain modulation. To investigate the potential interactions of EM2- and substance P (SP)-containing primary afferents and γ-amino butyric acid...
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Open AccessAutism-associated gene Dlgap2 mutant mice demonstrate exacerbated aggressive behaviors and orbitofrontal cortex deficits
As elegant structures designed for neural communication, synapses are the building bricks of our mental functions. Recently, many studies have pointed out that synaptic protein-associated mutations may lead to...
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A model of synaptic plasticity: activation of mGluR I induced long-term theta oscillations in medial septal diagonal band of rat brain slice
This study aimed to establish a model of synaptic plasticity by the activation of metabotropic glutamate receptor (mGluR) I in rat medial septal diagonal band (MSDB). Electrophysiological experiment was perfor...
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Open AccessBAIAP2 exhibits association to childhood ADHD especially predominantly inattentive subtype in Chinese Han subjects
Attention-deficit/hyperactivity disorder (ADHD) is a common chronic neurodevelopmental disorder with a high heritability. Much evidence of hemisphere asymmetry has been found for ADHD probands from behavioral ...
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Association between interleukin-1α C(−889)T polymorphism and Alzheimer’s disease: a meta-analysis including 12,817 subjects
Epidemiological studies have evaluated the association between interleukin-1 (IL-1)α C(−889)T polymorphism and Alzheimer’s disease (AD), but the results remain inconclusive. This meta-analysis was, therefore, ...
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An Event-Related Potential Study of Maternal Love in Mothers
Feeling is stable and implicit and can be explicated in concrete situations in the form of emotion. To map the time course of feeling processing, the present study explored electrophysiological responses relev...
