37 Result(s)
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Hossein Samadi Kafil
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Article
Open AccessPrevalence of the CRISPR-cas system and its association with antibiotic resistance in clinical Klebsiella pneumoniae isolates
CRISPR-Cas is a prokaryotic adaptive immune system that protects bacteria and archaea against mobile genetic elements (MGEs) such as bacteriophages plasmids, and transposons. In this study, we aimed to assess ...
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Molecular ty** of clinical multidrug-resistant Klebsiella pneumoniae isolates
Klebsiella pneumoniae is an opportunistic pathogen which is an important cause of hospital-acquired and antibiotic resistance infections. Therefore, this study aimed to determine the frequency of resistance to an...
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Crosslinking Chitosan with Silver-Sulfur Doped Graphene Quantum Dots: An Efficient Antibacterial Nanocomposite Hydrogel Films
Polysaccharides are among the most potent materials for wound dressing construction. In this study, antibacterial flexible hydrogel films were prepared through a novel crosslinking of biopolymeric chitosan (CS...
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Synthesis of Novel Antibacterial and Biocompatible Colistin-Loaded Cellulose/Manganese Oxide Nanocomposite Hydrogel Film
This study aims to design an innovative flexible nanocomposite film via the integration of MnO2 NPs into the biopolymeric carboxymethyl cellulose (CMC) hydrogel for improving its mechanical, swelling, and antibio...
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Antigenotoxicity and Cytotoxic Potentials of Cell-Free Supernatants Derived from Saccharomyces cerevisiae var. boulardii on HT-29 Human Colon Cancer Cell Lines
Microbial-derived postbiotics are of interest recently due to their lower side effects than chemotherapy for cancer treatment and prevention. This study aimed to investigate the potential antigenotoxic and cyt...
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Comparing the Effect of Probiotic and Fluconazole on Treatment and Recurrence of Vulvovaginal Candidiasis: a Triple-Blinded Randomized Controlled Trial
Vaginitis is a common problem in women. Candida albicans is responsible for more than 85% of vaginal fungal infections. The aim of this study was to compare the effects of probiotic and fluconazole on the treatme...
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Preeclampsia-Derived Exosomes Imbalance the Activity of Th17 and Treg in PBMCs from Healthy Pregnant Women
The disturbance of maternofetal immune tolerance is identified as one of the important issues in the pathology of preeclampsia (PE). PE exosomes are believed to possess significant roles in immune abnormalitie...
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Open AccessWhole-genome sequence analysis of clinically isolated carbapenem resistant Escherichia coli from Iran
The emergence of carbapenem-resistant Enterobacterales (CRE) continues to threaten public health due to limited therapeutic options. In the current study the incidence of carbapenem resistance among the 104 clini...
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Open AccessGenetic diversity of Mycobacterium tuberculosis isolates from northwest of Iran during COVID-19 era
Tuberculosis (TB) is considered one of the most infectious diseases in the world. In this study, we intended to examine the epidemiology of tuberculosis by MIRU-VNTR to define the changes that occur in the tra...
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Open AccessGentamicin-loaded chitosan/folic acid-based carbon quantum dots nanocomposite hydrogel films as potential antimicrobial wound dressing
To provide effective healing in the wound, various carbohydrate polymers are commonly utilized that are highly potent platforms as wound dressing films. In this work, novel antibacterial flexible polymeric hyd...
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Open AccessMap** age- and sex-specific HIV prevalence in adults in sub-Saharan Africa, 2000–2018
Human immunodeficiency virus and acquired immune deficiency syndrome (HIV/AIDS) is still among the leading causes of disease burden and mortality in sub-Saharan Africa (SSA), and the world is not on track to m...
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Investigation of SARS-CoV-2 RNA contamination in water supply resources of Tabriz metropolitan during a peak of COVID-19 pandemic
It is crucial to have access to clean water resources during the COVID-19 pandemic for hygiene, since virus infection through wastewater leaks in metropolitan areas can be a threat. Accurate monitoring of urba...
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Evaluation of CD39, CD73, HIF-1α, and their related miRNAs expression in decidua of preeclampsia cases compared to healthy pregnant women
The Preeclampsia (PE) molecular mechanisms are not fully revealed and different biological processes are involved in the pathogenesis of PE. We aimed to evaluate adenosine and hypoxia-related signaling molecul...
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Development and structural characterization of novel biomaterial polymeric films based on the mucilage extracted from Salvia mirzayanii seed gum incorporated with zinc oxide nanoparticles
This research aimed to produce packaging biomaterial films using the carbohydrate mucilage extracted from Salvia mirzayanii seed gum (SMSG) and to investigate the influence of adding zinc oxide nanoparticles (ZnO...
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Open AccessPolymorphism of the IL-10 gene in Azeri population of Iran
Interleukin (IL)-10 is one of the key interleukins in the immune system. It plays an anti-inflammatory role in body by inhibition of the synthesis of pro-inflammatory cytokines and reducing the expression of m...
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Open AccessIt is time to define an organizational model for the prevention and management of infections along the surgical pathway: a worldwide cross-sectional survey
The objectives of the study were to investigate the organizational characteristics of acute care facilities worldwide in preventing and managing infections in surgery; assess participants’ perception regarding...
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Open AccessEarly stage evaluation of colon cancer using tungsten disulfide quantum dots and bacteriophage nano-biocomposite as an efficient electrochemical platform
Recently, biosensors have become popular analytical tools for small analytes due to their high sensitivity and wide analytical range. In the present work, development of a novel biosensing method based on tung...
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Open AccessEvaluation of phenotypic and genotypic patterns of aminoglycoside resistance in the Gram-negative bacteria isolates collected from pediatric and general hospitals
The purpose of the current study was to evaluate the phenotypic and genotypic patterns of aminoglycoside resistance among the Gram-negative bacteria (GNB) isolates collected from pediatric and general hospital...
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Calix[4]arene-based thiosemicarbazide Schiff-base ligand and its transition metal complexes: synthesis and biological assessment
Thiosemicarbazides have the capability of killing the cancerous tumor cells and inhibit the growth of bacteria and fungus. Here, we designed and synthesized a calix[4]arene-based thiosemicarbazone Schiff-base ...
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Preparation, characterization, and antibacterial properties of hybrid nanofibrous scaffolds for cutaneous tissue engineering
Since polymeric nanofibrous scaffolds have been widely used in tissue regeneration, the risk of bacterial infections should not be neglected. In the present work, poly-caprolactone-silk fibroin-soluble eggshel...
