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Article
Open AccessPatients with ASPSCR1-TFE3 fusion achieve better response to ICI based combination therapy among TFE3-rearranged renal cell carcinoma
TFE3-rearranged renal cell carcinoma (TFE3-rRCC) is a rare but highly heterogeneous renal cell carcinoma (RCC) entity, of which the clinical treatment landscape is largely undefined. This study aims to evaluate a...
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Article
Open AccessFacile synthesis of hierarchical W18O49 microspheres by solvothermal method and their optical absorption properties
In this study, a simple route for the synthesis of hierarchical W18O49 assembled by nanowires is reported. The morphologies and formation of W18O49 single-crystal could be controlled by changing the concentration...
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Article
The applications of IL@MOFs for solid-state electrolytes in all-solid-state battery: a review
All-solid-state lithium batteries (ASSLBs) have aroused worldwide interests for their high safety and energy density. As known to all, solid-state electrolytes (SSEs) are one of the most important parts in ASS...
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Article
Open AccessIntegrated analysis of metabolome, transcriptome, and bioclimatic factors of Acer truncatum seeds reveals key candidate genes related to unsaturated fatty acid biosynthesis, and potentially optimal production area
Lipids found in plant seeds are essential for controlling seed dormancy, dispersal, and defenses against biotic and abiotic stress. Additionally, these lipids provide nutrition and energy and are therefore imp...
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Article
Open AccessParity-time symmetry enabled ultra-efficient nonlinear optical signal processing
Nonlinear optical signal processing (NOSP) has the potential to significantly improve the throughput, flexibility, and cost-efficiency of optical communication networks by exploiting the intrinsically ultrafas...
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Article
Chemotactic nanomotor for multimodal combined therapy of glioblastoma
Glioblastoma (GBM) is the most aggressive malignant brain tumor. Due to the infiltration and heterogeneity of GBM, the obstruction of the blood-brain barrier (BBB) and the unique immunosuppressive mechanism, i...
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Article
Open AccessFBXO22 promotes glioblastoma malignant progression by mediating VHL ubiquitination and degradation
Glioblastoma (GBM) is the most common malignant primary brain tumor. Despite comprehensive treatment with traditional surgery, radiotherapy, and chemotherapy, the median survival rate is <14.6% and the 5-year ...
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Article
Open AccessAn exposome atlas of serum reveals the risk of chronic diseases in the Chinese population
Although adverse environmental exposures are considered a major cause of chronic diseases, current studies provide limited information on real-world chemical exposures and related risks. For this study, we col...
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Article
Open AccessGenome-wide identification of SWEET genes reveals their roles during seed development in peanuts
Sugar Will Eventually be Exported Transporter (SWEET) proteins are highly conserved in various organisms and play crucial roles in sugar transport processes. However, SWEET proteins in peanuts, an essential le...
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Article
Open AccessPRMT1-mediated PGK1 arginine methylation promotes colorectal cancer glycolysis and tumorigenesis
Many types of cancer cells, including colorectal cancer cells (CRC), can simultaneously enhance glycolysis and repress the mitochondrial tricarboxylic acid (TCA) cycle, which is called the Warburg effect. Howe...
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Article
PMoO12@NH2-MIL-53(Fe)-derived iron molybdate/iron oxide with nitrogen-doped carbon nanocomposites as anodes for lithium-ion batteries
Transition metal oxides (TMOs) possess the distinct advantage of high theoretical specific capacity and are considered as one of the promising alternatives to carbon-based anode materials for lithium-ion batte...
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Article
The Ruminococcus bromii amylosome protein Sas6 binds single and double helical α-glucan structures in starch
Resistant starch is a prebiotic accessed by gut bacteria with specialized amylases and starch-binding proteins. The human gut symbiont Ruminococcus bromii expresses Sas6 (Starch Adherence System member 6), which ...
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Article
Open AccessDevelopment and validation of a predictive model based on clinical and MpMRI findings to reduce additional systematic prostate biopsy
To develop and validate a predictive model based on clinical features and multiparametric magnetic resonance imaging (mpMRI) to reduce unnecessary systematic biopsies (SBs) in biopsy-naïve patients with suspec...
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Chapter and Conference Paper
Reinforcement Learning for Combating Cyberbullying in Online Social Networks
In recent decades, social network holds a pivotal role for people’s communication, but it is also a particularly susceptible to cyberbullying due to their rapid information dissemination capabilities. The stat...
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Article
Open AccessEfficient and accurate numerical-projection of electromagnetic multipoles for scattering objects
In this paper, we develop an efficient and accurate procedure of electromagnetic multipole decomposition by using the Lebedev and Gaussian quadrature methods to perform the numerical integration. Firstly, we b...
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Article
Artificial intelligence as diagnostic aiding tool in cases of Prostate Imaging Reporting and Data System category 3: the results of retrospective multi-center cohort study
To study the effect of artificial intelligence (AI) on the diagnostic performance of radiologists in interpreting prostate mpMRI images of the PI-RADS 3 category.
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Article
Open AccessDeep learning discovery of macroscopic governing equations for viscous gravity currents from microscopic simulation data
Although deep learning has been successfully applied in a variety of science and engineering problems owing to its strong high-dimensional nonlinear map** capability, it is of limited use in scientific knowl...
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Article
Chief physician SUN Wuquan’s experience collection in treating neck-type cervical spondylosis with Tuina therapy
The article analyzes chief physician SUN Wuquan’s empirical characteristics in treating neck-type cervical spondylosis: disease differentiation combined with pattern differentiation, emphasizing the assessment...
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Article
CircPRRC2C Promotes the Oncogenic Phenotypes of Laryngeal Squamous Cell Carcinoma Cells via MiR-136-5p/HOXD11 Axis
The involvement of circular RNAs (circRNAs) in laryngeal squamous cell carcinoma (LSCC) carcinogenesis has gradually been proposed. Herein, we aimed to explore the function and mechanism of circPRRC2C in LSCC....
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Article
Neuroendocrine differentiation predicts the therapeutic efficacy of abiraterone and docetaxel as first-line therapy in metastatic castration-resistant prostate cancer
We aim to explore the predictive value of neuroendocrine differentiation (NED) in patients with metastatic castration-resistant prostate cancer (mCRPC) receiving abiraterone or docetaxel as first-line therapy.
