80 Result(s)

Article

Exogeneous energy supply and excitability of cells in embryonic atypical epidermis of Cynops cultured in vitro

Cells of in vitro cultured epidermis explants of ectoderm isolated at early gastrula stage, showed only weak excitability or even non-excitable at 6V when examined electrophy-siologically. If non-excitable explan...

Weilin Wu, Hsiaohui Chuang in Cell Research (1990)

Article

Bivariate genome scans incorporating factor and principal component analyses to identify common genetic components of alcoholism, event-related potential, and electroencephalogram phenotypes

Genetic components significantly contribute to the susceptibilities of alcoholism and its endophenotypes, such as event-related potential measures and electroencephalogram. An endophenotype is a correlated tra...

**g-** Lin, Colin Wu in BMC Genetics (2005)

Article

Dynamics and evolution of the inverted repeat-large single copy junctions in the chloroplast genomes of monocots

Various expansions or contractions of inverted repeats (IRs) in chloroplast genomes led to fluxes in the IR-LSC (large single copy) junctions. Previous studies revealed that some monocot IRs contain a trnH-rps19 ...

Rui-Jiang Wang, Chiao-Lei Cheng, Ching-Chun Chang, Chun-Lin Wu… in BMC Evolutionary Biology (2008)

Article

Automated DNA mutation detection using universal conditions direct sequencing: application to ten muscular dystrophy genes

One of the most common and efficient methods for detecting mutations in genes is PCR amplification followed by direct sequencing. Until recently, the process of designing PCR assays has been to focus on indivi...

Richard R Bennett, Hal E Schneider, Elicia Estrella, Stephanie Burgess… in BMC Genetics (2009)

Article

Inactivation of the fliY gene encoding a flagellar motor switch protein attenuates mobility and virulence of Leptospira interrogansstrain Lai

Pathogenic Leptospira species cause leptospirosis, a zoonotic disease of global importance. The spirochete displays active rotative mobility which may contribute to invasion and diffusion of the pathogen in hosts...

Sumei Liao, Aihua Sun, David M Ojcius, Senlin Wu, **fang Zhao, Jie Yan in BMC Microbiology (2009)

Article

Pellicle formation in Shewanella oneidensis

Although solid surface-associated biofilm development of S. oneidensis has been extensively studied in recent years, pellicles formed at the air-liquid interface are largely overlooked. The goal of this work was ...

Yili Liang, Haichun Gao, **grong Chen, Yangyang Dong, Lin Wu, Zhili He… in BMC Microbiology (2010)

Article

Increased intracellular calcium concentration causes electrical turbulence in guinea pig ventricular myocytes

Dysregulation of intracellular Ca²⁺ homeostasis is associated with various pathological conditions and arrhythmogenesis of the heart. The objective of this study was to investigate the effects of an acute increas...

**nRong Fan, JiHua Ma, Wei Wan, PeiHua Zhang, Chao Wang… in Science China Life Sciences (2011)

Article

Transcriptome analysis of Cymbidium sinense and its application to the identification of genes associated with floral development

Cymbidium sinense belongs to the Orchidaceae, which is one of the most abundant angiosperm families. C. sinense, a high-grade traditional potted flower, is most prevalent in China and some Southeast Asian countri...

Jianxia Zhang, Kunlin Wu, Songjun Zeng, Jaime A Teixeira da Silva… in BMC Genomics (2013)

Article

Genome-wide promoter methylation profile of human testis and epididymis: identified from cell-free seminal DNA

DNA methylation analysis is useful for investigation of male fertility in mammals, whereas the reliance on tissues limits the research on human. We have previously found the presence of high concentration of c...

Chunlin Wu, **aofang Ding, Honggang Li, Changhong Zhu, Chengliang **ong in BMC Genomics (2013)

Article

Expression quantitative trait loci infer the regulation of isoflavone accumulation in soybean (Glycine max L. Merr.) seed

Map** expression quantitative trait loci (eQTL) of targeted genes represents a powerful and widely adopted approach to identify putative regulatory variants. Linking regulation differences to specific genes ...

Yan Wang, Yingpeng Han, Weili Teng, Xue Zhao, Yongguang Li, Lin Wu… in BMC Genomics (2014)

Article

The Integrator complex controls the termination of transcription at diverse classes of gene targets

Complexes containing INTS3 and either NABP1 or NABP2 were initially characterized in DNA damage responses, but their biochemical function remained unknown. Using affinity purifications and HIV Integration targ...

Jeffrey R Skaar, Andrea L Ferris, **aolin Wu, Anita Saraf, Kum Kum Khanna… in Cell Research (2015)

Article

Genetic architecture, epigenetic influence and environment exposure in the pathogenesis of Autism

Autism spectrum disorder (ASD) is a spectral neurodevelopment disorder affecting approximately 1% of the population. ASD is characterized by impairments in reciprocal social interaction, communication deficits...

Li Yu, YiMing Wu, Bai-Lin Wu in Science China Life Sciences (2015)

Article

Parenting stress and affective symptoms in parents of autistic children

We examined parenting stress and mental health status in parents of autistic children and assessed factors associated with such stress. Participants were parents of 188 autistic children diagnosed with DSM-IV ...

Yun Gong, YaSong Du, HuiLin Li, **Yan Zhang, Yu An… in Science China Life Sciences (2015)

Article

Impact of RNA degradation on fusion detection by RNA-seq

RNA-seq is a well-established method for studying the transcriptome. Popular methods for library preparation in RNA-seq such as Illumina TruSeq® RNA v2 kit use a poly-A pulldown strategy. Such methods can caus...

Jaime I. Davila, Numrah M. Fadra, **aoke Wang, Amber M. McDonald… in BMC Genomics (2016)

Article

TLR3 activation induces S100A7 to regulate keratinocyte differentiation after skin injury

Human S100A7 (psoriasin) is highly expressed in psoriasis and other inflammatory diseases; however, the function of S100A7 in wound repair remains largely unknown. Here we demonstrated that skin injury increas...

Hu Lei, Yue Wang, Tian Zhang, Leilei Chang, Yelin Wu… in Science China Life Sciences (2017)

Article

Association analysis between HFM1 variations and idiopathic azoospermia or severe oligozoospermia in Chinese Men

Wenxiang Zhang, **aomin Song, Feng Ni, **bao Cheng… in Science China Life Sciences (2017)