Pharmacogenetics in Italy: current landscape and future prospects
Authors (first, second and last of 13)
Collection
Pharmacogenomics Beyond Single Common Genetic Variants
In this Collection, we invite original research articles, case reports, meta-analyses, and reviews that focus on associations between genetic variability with drug metabolism, response or toxicity. We particularly welcome reports that identify combinatorial variant effects in cis or trans, epigenetic variations, regulation of gene expression by non-coding RNAs as well as polygenic models for drug response and safety predictions. Pharmacogenetic and -genomic studies of both the germline and somatic genome will be considered. The Collection is furthermore open to implementation studies that demonstrate feasibility or outcomes of point-of-care genetic profiling.
Articles (7 in this collection)
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Association of lipid-lowering drugs with risk of sarcopenia: a drug target mendelian randomization study and meta-analysis
Authors (first, second and last of 7)
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Trace amine associated receptor 1: predicted effects of single nucleotide variants on structure-function in geographically diverse populations
Authors (first, second and last of 6)
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Prioritization of therapeutic targets for cancers using integrative multi-omics analysis
Authors (first, second and last of 11)
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Meta-analysis of the global distribution of clinically relevant CYP2C8 alleles and their inferred functional consequences
Authors (first, second and last of 6)
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Large-scale next generation sequencing based analysis of SLCO1B1 pharmacogenetics variants in the Saudi population
Authors (first, second and last of 6)
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The burden of rare variants in DPYS gene is a novel predictor of the risk of develo** severe fluoropyrimidine-related toxicity
Authors (first, second and last of 10)
