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Role of Extracellular Vesicles in Renal Inflammation and Fibrosis

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Renal Fibrosis: Mechanisms and Therapies

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 1165))

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Abstract

Extracellular vesicles (EVs) are the membrane-surrounded structures released by almost all types of cells. Accumulating evidences have suggested that EVs secretion is enhanced under stress conditions and have been associated with a large wide of cellular physiological and pathological processes. In this part, recent understanding about the generation and biological function of EVs was reviewed. Moreover, the role of EVs in renal inflammation and fibrosis and future challenges of EVs study in kidney disease were discussed.

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Acknowledgements

This chapter was modified from a paper reported by our group in J Cell Mol Med (Lv et al. 2019).

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Authors and Affiliations

  1. Institute of Nephrology, Zhong Da Hospital, Southeast University School of Medicine, Nan**g, China

    Lin-Li Lv

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  1. Lin-Li Lv
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Correspondence to Lin-Li Lv .

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Editors and Affiliations

  1. Zhongda Hospital, Southeast University School of Medicine, Southeast University, Nan**g, Jiangsu, China

    Bi-Cheng Liu

  2. Department of Medicine and Therapeutics, Li Ka Shing Institute of Health Sciences, Chinese University of Hong Kong, Hong Kong, Hong Kong

    Hui-Yao Lan

  3. Zhongda Hospital, Southeast University School of Medicine, Southeast University, Nan**g, Jiangsu, China

    Lin-Li Lv

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Lv, LL. (2019). Role of Extracellular Vesicles in Renal Inflammation and Fibrosis. In: Liu, BC., Lan, HY., Lv, LL. (eds) Renal Fibrosis: Mechanisms and Therapies. Advances in Experimental Medicine and Biology, vol 1165. Springer, Singapore. https://doi.org/10.1007/978-981-13-8871-2_22

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