Abstract
Aconitum plants (Wu Tou, Ranunculaceae family) have been widely used to treat various diseases, such as rheumatism, knee pain, herpes zoster, scabies, and other disorders in China for thousands of years. Aconitine was previously used as an antipyretic and analgesic. However, the clinical application of aconitine is limited by its high toxicity.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Ohno Y. Experimental approach to murder by aconite poisoning from the viewpoint of medicolegal toxicology. Nihon Hoigaku Zasshi. 2006;60(2):101–9.
Chan TY. Aconitum alkaloid poisoning related to the culinary uses of aconite roots. Toxins (Basel). 2014;6(9):2605–11.
Okazaki M, Kimura I, Kimura M. Aconitine-induced increase and decrease of acetylcholine release in the mouse phrenic nerve-hemidiaphragm muscle preparation. Jpn J Pharmacol. 1994;66(4):421–6.
Chan TY. Aconite poisoning. Clin Toxicol (Phila). 2009;47(4):279–85.
Beike J, et al. Determination of aconitine in body fluids by LC-MS-MS. Int J Legal Med. 2004;118(5):289–93.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
Copyright information
© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China
About this chapter
Cite this chapter
Yan, R., Li, L., Du, GH. (2018). Aconitine. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_58
Download citation
DOI: https://doi.org/10.1007/978-981-10-8022-7_58
Published:
Publisher Name: Springer, Singapore
Print ISBN: 978-981-10-8021-0
Online ISBN: 978-981-10-8022-7
eBook Packages: Biomedical and Life SciencesBiomedical and Life Sciences (R0)