Abstract
Gastrodin is extracted from Gastrodia elata, which is widely used for the treatment of vertigo, headache, neuralgia, neurasthenia syndrome, and brain traumatic syndrome. Studies showed that gastrodin has many pharmacological effects, including hypnosis, sedation, and anticonvulsive. At present, to reduce the frequency of administration, the fluctuations of blood drug concentration, as well as side effects, some new dosage forms have been developed in recent years, such as Gastrodia dispersible tablets, Gastrodia sustained-release tablet, sustained-release pellets and osmotic pump tablets, etc. Although gastrodin has been applied clinically, a lot of studies still need to be done to confirm the efficacy and safety of gastrodin, and the other compositions of Gastrodia elata are subjected to further investigation.
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References
Chen C, Li XS, Zhou JJ, et al. Advances in extraction and purification of Gastrodin. J Shaanxi Univ Technol (Nat Sci Ed). 2013;29(3):4–5.
Yang SL, Lan J, Xu JT. Research progress in Rhizoma gastrodiae. Chin Tradit Herb Drug. 2000;31(1):66–9.
Yu P, Yu DZ. Experimental research on the improvement of sleep function in certain Rhizoma gastrodiae products. Mod Prev Med. 2000;34(16):3056–7.
Zou N, Lu JT, et al. The sedative and hypnotic effect of gastrodin in mice. Lishizhen Med Mater Med Res. 2011;22(9):807–9.
Wang Q, Chen GS, Zeng S. Distribution and metabolism of gastrodin in rat brain. J Pharm Biomed Anal. 2008;46(2):399–4.
Qiu CL, Yi WJ. Gastrodin treatment of hypertonic headache in liver Yang. Mod J Integr Tradit Chin West Med. 201l;20(24):3045–6.
Shi L, Chen L, Zhang JL. 40 cases of gastrodin acupoint injection in the treatment of insomnia. J External Ther Tradit Chin Med. 2010;19(1):44.
Zhang Q, Yang YM, Yu GY. Effects of gastrodin injection on blood pressure and vasoactive substances in treatment of old patients with refractory hypertension: a randomized controlled trial. J China Int Med. 2008;6(7):695–9.
Miao K, Wang M, **e Z. An observation of the clinical effect of gastrodin in the treatment of coronary heart angina. Tian** Pharm. 2000;21(6):26–7.
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© 2018 Springer Nature Singapore Pte Ltd. and People's Medical Publishing House, PR of China
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Pang, XC., Liu, AL., Du, GH. (2018). Gastrodin. In: Natural Small Molecule Drugs from Plants. Springer, Singapore. https://doi.org/10.1007/978-981-10-8022-7_43
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DOI: https://doi.org/10.1007/978-981-10-8022-7_43
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