Abstract
A heavy demand in the use of living cells and tissues for clinical treatment of diseases, in transfusion and transplantation has generated the need to keep these cells in a viable condition outside the body. In order to achieve this goal, the science of tissue preservation had developed based mostly on the applications of low-temperature storage either in the liquid state above 0 °C of after freezing. This paper discusses the effects of cooling on cell structure and function. Applications of reduced temperature in clinical science fro cell and tissue preservation by selective destruction of unwanted cells as in cryosurgery are highlighted here.
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References
Fuller, B. J. and Grout, B. W. W., 1991, Clinical Applications of Cryobiology, CRC Press, Boca Raton, Florida
May, J. C. and Brown, F., 1992, Biological Product Freezing-Drying and Formulation, S. Karger AG, Basel, Switzerland
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© 2003 Springer Science+Business Media Dordrecht
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Yang, W.J., Mochizuki, S. (2003). Preservation of Biological Materials -Principles and Applications-. In: Kakaç, S., Smirnov, H.F., Avelino, M.R. (eds) Low Temperature and Cryogenic Refrigeration. NATO Science Series, vol 99. Springer, Dordrecht. https://doi.org/10.1007/978-94-010-0099-4_18
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DOI: https://doi.org/10.1007/978-94-010-0099-4_18
Publisher Name: Springer, Dordrecht
Print ISBN: 978-1-4020-1274-7
Online ISBN: 978-94-010-0099-4
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