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Can Echocardiography Provide Combined Assessment of Left Ventricular Function and Myocardial Perfusion?

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Contrast Echocardiography in Clinical Practice

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Abstract

While the relationship between coronary blood flow and myocardial function is complex and multifaceted, it can be summarized in one simplistic statement: reduction in coronary flow results in reduced myocardial perfusion leading to an ischemic cascade, the end-point of which is compromised ventricular function. Different methods used for the diagnosis of coronary heart disease are based on detection of these changes, either at rest or under stress. However, most of them focus on a single parameter, such as wall motion or myocardial perfusion, rather than providing comprehensive diagnosis based on the combined assessment of multiple variables. Thus, coronary angiography focuses on coronary anatomy to estimate coronary flow, nuclear imaging provides information on myocardial perfusion, and the echocardiographic diagnosis of ischemic heart disease is mainly based on the assessment of regional wall motion. It has been recognized that a technique capable of evaluating more than one variable in a single test would likely provide a more accurate and reliable diagnostic tool [1–2], and undoubtedly have an impact on the prognosis and risk stratification of patients with suspected ischemic heart disease. In addition, such a technique would be advantageous for the diagnosis of conditions characterized by a mismatch between blood supply and myocardial function, such as hibernating or stunned myocardium [3–5].

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  1. Victor Mor-Avi
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  2. R. Parker Ward
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  3. Roberto M. Lang
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Mor-Avi, V., Ward, R.P., Lang, R.M. (2004). Can Echocardiography Provide Combined Assessment of Left Ventricular Function and Myocardial Perfusion?. In: Contrast Echocardiography in Clinical Practice. Springer, Milano. https://doi.org/10.1007/978-88-470-2125-9_13

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