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Superhydrophobic Devices Molecular Detection

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Novel Approaches for Single Molecule Activation and Detection

Part of the book series: Advances in Atom and Single Molecule Machines ((AASMM))

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Abstract

Recent advances in the single-molecule detection and manipulation provided unexpected solutions for the understanding of the physio-pathological behavior of individual biological macromolecules. Modern techniques of patterning at the micro- and nanometer scale combined with chemical treatments are being used to create surfaces that stretch the hydrophobic behavior to the limit. The ability to create surfaces with high static water contact angles (usually greater than 150°) is essential for a variety of applications, ranging from the development of biosensors to the implementation of sensitive and reliable single-molecule collection and sample preparation methods. Thus, superhydrophobic devices could be considered as nano-biotechnological single-molecule detection tools that can be applied to a wide range of high-resolution studies. To outline the paper, single-molecule detection topics and theoretical principles of superhydrophobicity are first introduced. A comprehensive overview is then given, describing how different types of devices with superhydrophobic surfaces are realized. Finally, the usefulness of the presented devices for a wide range of applications and the concluding comments are proposed.

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Author information

Authors and Affiliations

  1. Nanostructures, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genoa, Italy

    Tania Limongi, Lorenzo Ferrara, Manola Moretti, Ermanno Miele, Angelo Accardo & Francesco Gentile

  2. Neuroscience and Brain Technology, Istituto Italiano di Tecnologia, via Morego 30, 16163, Genoa, Italy

    Tania Limongi

  3. Physical Science and Engineering Division, King Abdullah University of Science and Technology, Bldg. 3, 3rd floor, Office # 3235, Thuwal, 23955-6900, Kingdom of Saudi Arabia

    Tania Limongi, Gobind Das, Monica Marini & Enzo Di Fabrizio

  4. Computer, Electrical and Mathematical Sciences and Engineering (CEMSE) Division, King Abdullah University of Science and Technology, Thuwal, 23955-6900, Kingdom of Saudi Arabia

    Manola Moretti

  5. Lab. BIONEM, Dipartimento di Medicina Sperimentale e Clinica, Università degli Studi Magna Graecia di Catanzaro, viale Europa, loc. Germaneto , 88100, Catanzaro, Italy

    Raffaella Raimondo & Francesco Gentile

Authors
  1. Tania Limongi
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  2. Lorenzo Ferrara
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  3. Gobind Das
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  4. Manola Moretti
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  5. Monica Marini
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  6. Ermanno Miele
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  7. Angelo Accardo
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  8. Raffaella Raimondo
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  9. Francesco Gentile
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  10. Enzo Di Fabrizio
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Corresponding authors

Correspondence to Tania Limongi or Enzo Di Fabrizio .

Editor information

Editors and Affiliations

  1. Department of Neuroscience and Neurotechnology, University of Genoa The Italian Institute of Technology, Genoa, Italy

    Fabio Benfenati

  2. Nanostructures Department, The Italian Institute of Technology, Genoa, Italy

    Enzo Di Fabrizio

  3. Neuroscience Area, Scuola Internazionale Superiore di Studi, Trieste, Italy

    Vincent Torre

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© 2014 Springer-Verlag Berlin Heidelberg

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Limongi, T. et al. (2014). Superhydrophobic Devices Molecular Detection. In: Benfenati, F., Di Fabrizio, E., Torre, V. (eds) Novel Approaches for Single Molecule Activation and Detection. Advances in Atom and Single Molecule Machines. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-43367-6_4

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