Abstract
The nucleus is the main centre for storage of genetic information and for regulation of gene expression. Virtually all of the cellular DNA is now known to be nuclear. Chloroplasts and mitochondria contain their own DNA, but the informational content and amount of DNA in these organelles is very small relative to the nuclear genome. Control of transcription of nuclear DNA is of fundamental importance in the growth and development of cells and is discussed in Chapter 2. Precursor rRNA, rRNA and tRNA, are major species of nuclear RNA. However these are considered in detail elsewhere in this book and are not discussed in the present chapter which is devoted to other RNA species that occur in the nucleus.
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Armstrong, J. A., Edmonds, M., Nakazato, H., Phillips, B. A., Vaughan, M. H.: Science 176, 526 (1972).
Aronson, A. I.: Nature New Biol. 235, 40 (1972).
Artman, M., Roth, J.S.: J. Mol. Biol. 60, 291 (1971).
Atsmon, A., Spitnik-Elson, P., Elson, D.: J. Mol. Biol. 45, 125 (1969).
Attardi, G., Parnas, H., Hwang, M. I. H., Attardi, B.: J. Mol. Biol. 20, 145 (1966).
Axel, R., Schlom, J., Spiegelman, S.: Proc. Nat. Acad. Sci. U.S. 69, 535 (1972).
Baltimore, D., Huang, A.S.: J. Mol. Biol. 47, 263 (1970).
Bekhor, I., Kung, G.K., Bonner, J.: J. Mol. Biol. 39, 351 (1969).
Bernhardt, D., Darnell, J. E.: J. Mol. Biol. 42, 43 (1969).
Birnboim, H. C., Pene, J.J., Darnell, J. E.: Proc. Nat. Acad. Sci. U.S. 58, 320 (1967).
Bishop, J.O., Pemberton, R., Baglioni: Nature New Biol. 235, 231 (1972).
Bonner, J., Huang, R.C.C., Maheshwari, N.: Proc. Nat. Acad. Sci. U.S. 47, 1548 (1961).
Bonner, J., Widholm, J.: Proc. Nat. Acad. Sci. U.S. 57, 1397 (1967).
Bucher, N.L.R.: Intern. Rev. Cytol. 15, 245 (1963).
Burr, H., Lingrel, J. B.: Nature New Biol. 233, 41 (1971).
Busch, H.: In Methods in enzymology (Grossman, L., and Moldave, K., eds.), vol. 12, part A, p.421.New York: Academic Press 1967.
Busch, H., Ro-Choi, T. S., Prestayko, A.W., Shibata, H., Crooke, S. T., El-Khatib, S. M., CHOI, Y. C., Mauritzen, C. M.: Perspectives Biol. Med. 15, 117 (1971).
Chauveau, J., Moule, Y., Rouiller, C.: Exp. Cell Res. 11, 317 (1956).
Church, R.B., Luther, S.W., Mccarthy, B.J.: Biochim. Biophys. Acta 190, 30 (1969).
Church, R.B., Mccarthy, B.J.: Proc. Nat. Acad. Sci. U.S. 58, 1547 (1967).
Church, R.B., Mccarthy, B.J.: Biochim. Biophys. Acta 199, 103 (1970).
Clason, A. E., Burdon, R. H.: Nature 223, 1063 (1969).
Clegg, J. C. S., Arnstein, H. R.V.: Eur. J. Biochem. 13, 149 (1970).
Colby, C., Duesberg, P. H.: Nature 222, 940 (1969).
Commerford, S. L., Delihas, N.: Proc. Nat. Acad. Sci. U.S. 56, 1759 (1966).
Cooper, H. L.: J. Biol. Chem. 244, 1946 (1969).
Cooper, H.L.: Nature New Biol. 234, 272 (1971).
Cooper, H.L., KAY, J.E.: Biochim. Biophys. Acta 174, 503 (1969).
Coutelle, C, Ryskov, A. P., Georgiev, G. P.: Febs Lett. 12, 21 (1970).
Cozzone, A., Marchis-Mouren, G.: Biochemistry 6, 3911 (1967).
Dahmus, M. E., Mcconnell, D.J.: Biochemistry 8, 1524 (1969).
Daneholt, B., Svedhem, L.: Exp. Cell Res. 67, 263 (1971).
Darnell, J. E.: Bacteriol. Rev. 32, 262 (1968).
Darnell, J. E., Philipson, L., Wall, R., Adesnik, M.: Science 174, 507 (1971a).
Darnell, J. E., Wall, R., Tushinski, R.J.: Proc. Nat. Acad. Sci. U.S. 68, 1321 (1971b).
De Filippes, F. M.: Biochim. Biophys. Acta 199, 562 (1970).
De Maeyer, E., De Maeyer-Guignard, J., Montagnier, L.: Nature New Biol. 229, 109 (1971).
Drews, J., Brawerman, G., Morris, H. P.: Eur. J. Biochem. 3, 284 (1968).
Edmonds, M., Abrams, R.: J. Biol. Chem. 235, 1142 (1960).
Edmonds, M., Vaughan, M.H., Nakazato, H.: Proc. Nat. Acad. Sci. U.S. 68, 1336 (1971).
Enger, M.D., Walters, R. A.: Biochemistry 9, 3551 (1970).
Fakan, S., Bernhard, W.: Exp. Cell Res. 67, 129 (1971).
Fisher, R.F., Holbrook, D.J., Irvin, J. L.: J. Cell Biol. 17, 231 (1963).
Georgiev, G. P.: Progr. Nucl. Acid Res. Mol. Biol. 6, 259 (1967).
Georgiev, G. P.: J. Theoret. Biol. 25, 473 (1969).
Goldstein, L., Mlcou, J.: J. Biophys. Biochem. Cytol. 6, 1 (1959).
Goldstein, L., Plaut, W.: Proc. Nat. Acad. Sci. U.S. 41, 874 (1955).
Goldstein, L., Rao, M.V. N., Prescott, D. M.: Ann. Embryo Morph., Suppl. 1, 189 (1969).
Goldstein, L., Trescorr, O. H.: Proc. Nat. Acad. Sci. U.S. 67, 1367 (1970).
Green, M.: Ann. Rev. Biochem. 39, 701 (1970).
Green, M., Cartas, M.: Proc. Nat. Acad. Sci. U.S. 69, 791 (1972).
Green, M., Parsons, J.T., PISA, M., Fu**aga, K., Caffier, H., Landgraf-Leurs, 1.: Cold Spring Harbor Symp. Quant. Biol. 35, 803 (1970).
Greenberg, J. R., Perry, R. P.: J. Cell Biol. 50 774 (1971).
Harel, L., Montagnier, L.: Nature New Biol. 229106 (1971).
Harris, H.: Biochem. J. 73, 362 (1959).
Heiberg, R., Olsnes, S., Pihl, A.: Febs Lett. 18, 169 (1971).
Hellung-Larsen, P., Frederiksen, S.: Biochim. Biophys. Acta 262, 290 (1972).
Heyden, H.W., Zachau, H.G.: Biochim. Biophys. Acta 232, 651 (1971).
Heywood, S.M.: Proc. Nat. Acad. Sci. U.S. 67, 1782 (1970).
Holmes, D. S., Mayfield, J. E., Sander, G., Bonner, J.: Science 177, 72 (1972).
Honig, G., Rabinowitz, M.: Science 149, 1504 (1965).
Houssais, J. F., Attardi, G.: Proc. Nat. Acad. Sci. U.S. 56, 616 (1966).
Hoyer, B. H., Mccarthy, B. J., Bolton, E.T.: Science 140, 1408 (1963).
Huang, R.C., Bonner, J.: Proc. Nat. Acad. Sci. U. S. 54, 960 (1965).
Huang, R.C.C., Huang, P.C.: J. Mol. Biol. 39, 365 (1969).
Hunt, J.A., Peter, O.F., Johnson, B.E.: Proc. Aust. Biochem. Soc. 5, 34 (1972).
Hunt,T., Ehrenfeld, E.: Nature 230, 91 (1971).
Jacobson, R. A., Bonner, J.: Biochem. Biophys. Res. Commun. 33, 716 (1968).
Jacobson, R. A., Bonner, J.: Arch. Biochem. Biophys. 146, 557 (1971).
Jaenisch, R.: Nature New Biol. 235, 46 (1972).
Jeanteur, P., Amaldi, F., Attardi, G.: J. Mol. Biol. 33, 757 (1968).
Jelinek, W., Darnell, J. E.: Proc. Nat. Acad. Sci. U.S. 69, 2537 (1972).
Kates, J.: Cold Spring Harbor Symp. Quant. Biol. 35, 743 (1970).
Kempf, J., Mandel, P.: Bull. Soc. Chim. Biol. 51, 1121 (1969).
Kimball, P.C., Duesberg, P. H.: J. Virol. 7, 697 (1971).
Kirby, K. S.: In Methods in enzymology (Grossman, L. and Moldave, K., eds.), vol. 12, part B, p. 87. New York and London: Academic Press 1968.
Korn, D., Protass, J.J., Leive, L.: Biochem. Biophys. Res. Commun. 19, 473 (1965).
Kruh, J.: In Methods in enzymology (Grossman, L., and Moldave, K., eds.), vol. 12, part A, p. 609. New York and London: Academic Press 1967.
Lai, M.M.C., Duesberg, P. H.: Nature 235, 383 (1972).
Laszlo, J., Miller, D.S., Mccarty, K.S., Hochstein, P.: Science 151, 1007 (1966).
Leader, D. P., Klein-Bremhaar, H., Wool, I. G., Fox, A.: Biochem. Biophys. Res. Commun. 46, 215 (1972).
Lee, S.Y., Mendecki, J., Brawerman, G.: Proc. Nat. Acad. Sci. U. S. 68, 1331 (1971).
Lim, L., Canellakis, E. S.: Nature 227, 710 (1970).
Lindberg, U., Darnell, J. E.: Proc. Nat. Acad. Sci. U.S. 65, 1089 (1970).
Mach, B., Vassalli, P.: Science 150, 662 (1965).
Mathews, M. B.: Nature 228, 661 (1970).
Mayfield, J. E., Bonner, J.: Proc. Nat. Acad. Sci. U. S. 68, 2652 (1971).
Melli, M, Pemberton, R. E.: Nature New Biol. 236, 172 (1972).
Mendecki, J., Lee, S.Y., Brawerman, G.: Biochemistry 11, 792 (1972).
Mendecki, J., Minc, B., Chorazy, M.: Biochem. Biophys. Res. Commun. 36, 494 (1969).
Menzies, R. A., Press, G. D., Gold, P. H., Hendley, D. D., Strehler, B. L.: Cell and Tissue Kinetics 2, 133 (1969).
Monckton, R. P., Naora, H.: In preparation (1972).
Montagnier, L.: Compt. Rend. Ser. D. 267, 1417 (1968).
Moriyama,Y., Hodnett, J.L., Prestayko, A.W., Busch, H.: J. Mol. Biol. 39, 335 (1969).
Moriyama,Y., IP, P., Busch, H.: Biochim. Biophys. Acta 209, 161 (1970).
Muramatsu, M., Fujisawa,T.: Biochim. Biophys. Acta 157, 476 (1968).
Nakamura,T., Prestayko, A.W., Busch, H.: J. Biol. Chem. 243, 1368 (1968).
Naora, H.: J. Biophys. Biochem. Cytol. 3, 949 (1957).
Naora, H.: In preparation (1972).
Naora, H., Kodaira, K.: Biochim. Biophys. Acta 161, 276 (1968).
Naora, H., Kodaira, K.: Biochim. Biophys. Acta 182, 469 (1969).
Naora, H., Kodaira, K.: Biochim. Biophys. Acta 209, 196 (1970).
Naora, H., Kodaira, K.: Unpublished observations (1972).
Naora, H., Kodaira, K., Pritchard, M. J.: Biochim. Biophys. Acta 246, 280 (1971).
Naora, H., Naora, H., Brachet, J.: J. Gen. Physiol. 43, 1083 (1960).
Naora, H., Pritchard, M.J.: Biochim. Biophys. Acta 246, 269 (1971).
Niehaus, W. G., Barnum, C. P.: J. Biol. Chem. 239, 1198 (1964).
Noll., H., Stutz, E.: In Methods in enzymology (grossman, L., and moldave, K., eds.), vol. 12, part B, p. 129. New York and London: Academic Press 1968.
Pemberton, R.F., Baglioni, C.: J. Mol. Biol. 65, 531 (1972).
Penman, S., Fan, H., Perlman, S., Rosbash, M., Weinberg, R., Zylber, E.: Cold Spring Harbor Symp. Quant. Biol. 35, 561 (1970).
Penman, S., Scherrer, K., Becker, Y., Darnell, J.E.: Proc. Nat. Acad. Sci. U.S. 49, 654 (1963).
Penman, S., Vesco, C., Penman, M.: J. Mol. Biol. 34, 49 (1968).
Perry, R. P.: Exp. Cell Res. 29, 400 (1963).
Perry, R. P., Errera, M., Hell, H., Durwald, H.: J. Biophys. Biochem. Cytol. 11, 1 (1961).
Perry, R. P., Kelley, D.E.: J. Cell Physiol. 76, 127 (1970).
Phillipson, L., Wall, R., Glickman, R., Darnell, J.E.: Proc. Nat. Acad. Sci. U.S. 68, 2806 (1971).
Prescott, D. M.: Exp. Cell Res. 19, 29 (1960).
Prestayko, A., Busch, H.: Biochim. Biophys. Acta 169, 327 (1968).
Rein, A.: Biochim. Biophys. Acta 232, 306 (1971).
Rein, A., Penman, S.: Biochim. Biophys. Acta 190, 1 (1969).
Revel, M., Hiatt, H.H.: Proc. Nat. Acad. Sci. U.S. 51, 810 (1964).
Ro-Choi,T.S., Moriyama,Y., Choi, Y.C., Busch, H.: J. Biol. Chem. 245, 1970 (1970).
Ro-Choi,T. S., Reddy, R., Henning, D., Takano,T., Taylor, C.W., Busch, H.: J. Biol. Chem. 247, 3205 (1972).
Roizman, B., Bachenheimer, S., Wagner, E. K., Savage, T.: Cold Spring Harbor Symp. Quant. Biol. 35, 753 (1970).
Ryskov, A. P., Farashyan, V.R., Georgiev, G. D.: Febs Lett. 20, 355 (1972).
Sambrook, J., Westphal, H., Srinivasan, P. R., Dulbecco, R.: Proc. Nat. Acad. Sci. U.S. 60, 1288 (1968).
Scherrer, K., Marcaud, L., Zajdela, F., London, I. M., Gross, F.: Proc. Nat. Acad. Sci. U.S. 56, 1571 (1966).
Schochetman, G., Perry, R. P.: J. Mol. Biol. 63, 591 (1972).
Shearer, R., Mccarthy, B.J.: Biochemistry 6, 283 (1967).
Shearer, R.W., Smuckler, E.A.: Cancer Res. 32, 339 (1972).
Sheldon, R., Jurale, C., Kates, J.: Proc. Nat. Acad. Sci. U.S. 69, 417 (1972).
Shih,T.Y., Bonner, J.: Biochim. Biophys. Acta 182, 30 (1969).
Sibatani, A.: Progr. Biophys. Mol. Biol. 16, 15 (1966).
Sibatani, A.: Personal communication (1972).
Siebert, G.: In Methods in cancer research (Busch, H., ed.), vol. 2, p. 287. New York: Academic Press 1967.
Sivolap,Y.M., Bonner, J.: Proc. Nat. Acad. Sci. U.S. 68, 387 (1971).
Soeiro, R., Amos, H.: Biochim. Biophys. Acta 129, 406 (1966).
Soeiro, R., Darnell, J. E.: J. Cell Biol. 44, 467 (1970).
Soeiro, R., Vaughan, M. H., Warner, J. R., Darnell, J.E.: J. Cell Biol. 39, 122 (1968).
Srinivasan, P. R., Borek, E.: Science 145, 548 (1964).
Steele, W J, Busch, H.: In Methods in cancer research (BuscH, H., ed.), vol. 3, p. 61. New York: Academic Press 1967.
Stepanov, A.S., Voronina, A.S., Ovchinnikov, L. P., Spirin, A.S.: Febs Lett. 18, 13 (1971).
Stern, H.: In Methods in enzymology (Grossman, L., and Moldave, K., eds.), vol. 12, part B, p. 100. New York and London: Academic Press 1968.
Stern, R., Friedman, R. M.: Biochemistry 10, 3635 (1971).
Stollar, V., Stollar, B.D.: Proc. Nat. Acad. Sci. U.S. 65, 993 (1970).
Szeszak, F., Pihl, A.: Febs Lett. 20, 177 (1972).
Tonegawa, S., Walter, G., Bernardini, A., Dulbecco, R.: Cold Spring Harbor Symp. Quant. Biol. 35, 823 (1970).
Wall, R., Darnell, J.E.: Nature New Biol. 232, 73 (1971).
Wang, T.Y.: In Methods in enzymology (Grossman, L., and Moldave, K., eds.), vol.12, part A, p. 417. New York and London: Academic Press 1967.
Wang,T.Y.: In Methods in enzymology (Grossman, L., and Moldave, K., eds.), vol.12, part B, p. 115. New York and London: Academic Press 1968.
Warner, J., Soeiro, R., Birnboim, C., Darnell, J.E.: J. Mol. Biol. 19, 349 (1966).
Watts, J.W., Harris, H.: Biochem. J. 72, 149 (1959).
Weinberg, R. A., Penman, S.: J. Mol. Biol. 38, 289 (1968).
Weinberg, R. A., Penman, S.: Biochim. Biophys. Acta 190, 10 (1969).
Whitelam, J.M., Naora, H.: Biochim. Biophys. Acta 272, 425 (1972).
Whitely, A. H., Mccarthy, B. J., Whiteley, H.R.: Proc. Nat. Acad. Sci. U.S. 55, 519 (1966).
Willems, M., Wagner, E., Laing, R., Penman, S.: J. Mol. Biol. 32, 221 (1968).
Yamashita, A., Naora, H.: Japanese J. Haemat., in press (1972).
Zapisek, W.F., Saponara, A. G., Enger, M.D.: Biochemistry 8, 1170 (1969).
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Naora, H. (1973). Nuclear RNA. In: Stewart, P.R., Letham, D.S. (eds) The Ribonucleic Acids. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-00499-9_3
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