Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

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Abstract

Metastatic lesions to the eye are now widely recognized as the most common neoplasm of this organ. Of historic interest is the fact that the frequency of metastatic disease to the eye, as compared to primary intraocular tumors, was debated as recently as 1976, in a paper by Francois and Hanssens. After reviewing the literature, these authors commented that ‘many authors think that intraocular metastases are much more common and could be the most frequent malignant tumor of the eye, although other authors consider the malignant melanomas of the choroid to be the most frequent.’ Reports of metastatic disease to the eye and the orbit can be found in the medical literature throughout the last century. Albert et al. (1967) were the first to document the frequency of ocular metastases.

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References

  • Albert DM, Rubenstein RA, Scheie HG (1967a) Tumor metastases to the eye. Part I: Incidence in 213 adult patients with generalized malignancy. Am J Ophthalmol 63:723–726

    PubMed  CAS  Google Scholar 

  • Albert DM, Rubenstein RA, Scheie HG (1967b) Tumor metastases to the eye. Part II: Clinical study in infants and children. Am J Ophthalmol 63:727–732

    PubMed  CAS  Google Scholar 

  • Albert DM, Zimmermann AW, Zeidmann I (1967c) Tumor metastases to the eye. Part III: The fate of circulating tumor cells to the eye. Am J Ophthalmol 63:733–738

    PubMed  CAS  Google Scholar 

  • Bloch RS, Gartner S (1971) The incidence of ocular metastatic carcinoma. Arch Ophthalmol 85:673–675

    Article  PubMed  CAS  Google Scholar 

  • Chu FCH, Huh SH, Nisce LZ, Simpson LD (1977) Radiation therapy of choroid metastases from breast cancer. Int J Radiat Biol Phys 2:273–279

    Article  CAS  Google Scholar 

  • Dabski K (1985) Breast carcinoma metastatic to eyelids: case report and review of the literature. J Surg Oncol 23:233–236

    Article  Google Scholar 

  • Ferry AP (1973) The biological behavior and pathological features of carcinoma metastatic to the eye and orbit. Trans Am Ophthalmol Soc 71:373–425

    PubMed  CAS  Google Scholar 

  • Francois J, Hanssens H (1976) Intraocular metastases as first sign of generalized carcinomatosis. Ann Ophthalmol 8:405–419

    PubMed  CAS  Google Scholar 

  • Frank KW, Sugar HS, Shermann AI (1979) Anterior segment metastases from an ovarian choriocarcinoma. Am J Ophthalmol 87:778–782

    PubMed  CAS  Google Scholar 

  • Gragoudas ES (1989) Current treatment of metastatic choroidal tumors. Oncology 3:103–108

    PubMed  CAS  Google Scholar 

  • Ham JA, Cann NJ (1988) Testicular cancer presenting as a red swollen lid. Br J Ophthalmol 72:868–870

    Article  PubMed  CAS  Google Scholar 

  • Hirst LW, Reich I, Galbraith IEK (1979) Primary cutaneous malignant melanoma metastatic to the iris. Br J Ophthalmol 63:165–168

    Article  PubMed  CAS  Google Scholar 

  • Maor M, Chan RC, Young SE (1977) Radiotherapy of choroidal metastases: breast cancer as a primary site. Cancer 40:2081–2086

    Article  PubMed  CAS  Google Scholar 

  • McCormick B, Ellsworth R, Abramson D, Haik B (1988) Radiation therapy for retinoblastoma: comparison of results with lens sparing versus lateral beam techniques. Int J Radiat Oncol Biol Phys 15:567–574

    Article  PubMed  CAS  Google Scholar 

  • Mewis L, Young SE (1982) Breast carcinoma metastatic to the choroid. Ophthalmology 89:147–151

    PubMed  CAS  Google Scholar 

  • Nelson CC, Hertzberg BS, Klintworth GK (1983) A histopathologic study of 716 unresected eyes in patients with cancer at the time of death. Am J Ophthalmol 95: 788–793

    Article  PubMed  CAS  Google Scholar 

  • Reddy S, Saxena VS, Hendrickson F, Deutsch W (1981) Malignant metastatic disease of the eye: management of an uncommon complication. Cancer 47: 810–812

    Article  PubMed  CAS  Google Scholar 

  • Röttinger E, Heckemann R, Scherer E, et al. (1976) Radiation therapy of choroidal metastases from breast cancer. Graeftes Arch Clin Exp Ophthalmol 200: 243–250

    Article  Google Scholar 

  • Shields JA (1983) Diagnosis and management of intraocular tumors. C.V. Mosby, St. Louis, pp 278–321

    Google Scholar 

  • Stephens RF, Shields JA (1979) Diagnosis and management of cancer metastatic to the uvea. A study of 70 cases. Ophthalmology 86:1336–1349

    PubMed  CAS  Google Scholar 

  • Wyzinski P, Rootman I, Wood W (1981) Simultaneous bilateral iris metastases from renal cell carcinoma. Am J Ophthalmol 92:206–209

    PubMed  CAS  Google Scholar 

  • Young SE, Cruciger M, Lukeman I (1979) Metastatic carcinoma to the retina: case report. Ophthalmology 86:1350–1354

    PubMed  CAS  Google Scholar 

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© 1993 Springer-Verlag Berlin Heidelberg

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McCormick, B., Harrison, L.B. (1993). Radiation Therapy of Choroidal Metastases. In: Alberti, W.E., Sagerman, R.H. (eds) Radiotherapy of Intraocular and Orbital Tumors. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-97011-5_11

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  • DOI: https://doi.org/10.1007/978-3-642-97011-5_11

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-97013-9

  • Online ISBN: 978-3-642-97011-5

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