Abstract
The nerve action potentials were quite early recognized as oscillatory phenomena resembling certain rhythmical, chemical reactions at metal (Fe, Cr) interfaces (Ostwald, Lillie, Franck) and were described mathematically as ‘relaxation oscillations’ (Bethe, van der Pool, Bonhoeffer, Franck, Fitzhugh, and others). Many features exhibited by living, exitable tissues (nerve and heart) could be reproduced on these metallic systems, as all-or-non responses, threshold, bistability etc. The ‘energy’ driving the oscillations was obtained from electrochemical reactions.
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References
A. Papers describing the membrane oscillator, experiments, and theories
Teorell, T.: Acta physiol. scand. 31, suppl. 268 (preliminary communication) (1954).
Teorell, T.: A contribution to the knowledge of the rhythmical transport processes of salt and water. Exp. Cell Res. Suppl. 3, 339 (1955).
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Teorell, T.: Electrokinetic membrane processes in relation to properties of excitable tissues. II. Some theoretical considerations. (Basic equations, description of graphical methods of solving non-linear differential equations, i.e. the ‘isocline method’.) J. gen. Physiol. 42, 847 (1959).
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Teorell, T.: The ion flux across membranes during electro-diffusion and convection. (Theory for ion flux in single salt/porous membrane systems.) Acta physiol. scand. 62, 293 (1964).
B. The electrohydraulic excitability analog
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Teorell, T.: Application of a voltage-clamp to the electro-hydraulic nerve analog. (Analog computation of voltage clamp responses, discussion of nerve voltage clamps.) Acta Soc. Med. upsalien. 65, 231 (1960).
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D. Some references to recent works by other authors
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Teorell, T. (1969). Oscillatory Phenomena in a Porous, Fixed Charge Membrane. In: Passow, H., Stämpfli, R. (eds) Laboratory Techniques in Membrane Biophysics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-87259-4_11
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DOI: https://doi.org/10.1007/978-3-642-87259-4_11
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