SpringerLink
Log in

Hepatologie II

  • Conference paper
90. Kongreß

Part of the book series: Verhandlungen der Deutschen Gesellschaft für Innere Medizin ((VDGINNERE,volume 90))

  • 31 Accesses

Zusammenfassung

Der Echinococcus alveolaris (multilocularis) wächst beim Menschen wie ein maligner Tumor expansiv, infiltrativ destruierend und metastasierend. Die einzige Heilungsmöglichkeit besteht in einer kompletten Resektion. Weil die Echinokokkose schleichend beginnt und die Symptome sehr uncharakteristisch sind, wird die Diagnose oft erst zu einem Zeitpunkt gestellt, wenn die Echinokokkose nicht mehr kurativ resezierbar ist. Tierexperimentelle Untersuchungen [1, 3] und zahlreiche klinische Beobachtungen [7], z. T. in Form prospektiver Studien [5, 6] haben gezeigt, daß durch Mebendazol, ein Benzimidazolderivat, das weitere Wachstum der alveolären Echinokokkose verhindert, die Metacestoden aber nicht abgetötet werden können.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

Chapter
GBP 19.95
Price includes VAT (United Kingdom)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
GBP 39.16
Price includes VAT (United Kingdom)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
GBP 54.99
Price includes VAT (United Kingdom)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

Literatur

  1. Campbell WC, Blair LS (1974) Treatment of the cystic stage of Taenia crassiceps and Echinococcus multilocu1aris in laboratory animals. J ParasitoI 60: 1053–1054

    Article  CAS  Google Scholar 

  2. Dawson M et al. (1982) The pharmacokinetics and bioavai1ability of mebendazole in man: A pilot study using 3H-mebendazole. Br J Clin PharmacoI 14: 453–455

    Article  CAS  Google Scholar 

  3. Eckert J, Pohlenz J (1976) Zur Wirkung von Mebendazol auf Metazestoden von Mesocestoides corti und Echinococcus multilocularis. Tropenmed Parasitol 27: 247–262

    PubMed  CAS  Google Scholar 

  4. Junge U, Mohr W (1983) Mebendazol-Hepatitis. Z Gastroenterol 21: 736–738

    PubMed  CAS  Google Scholar 

  5. Kern P (1983) Human echinococcosis: follow-up of 23 patients treated with mebendazole. Infection 11: 17–24

    Article  PubMed  CAS  Google Scholar 

  6. Müller E et al. (1982) Treatment of human echinococcosis with mebendazole: preliminary observations in 28 patients. Hepatogastroentero1 29: 236–239

    Google Scholar 

  7. Schantz PM et al. (1982) Chemotherapy for larval echinococcosis in animals and humans: report of a workshop. Z Parasitenkd 67: 5–26

    Article  PubMed  CAS  Google Scholar 

  8. Seitz R et al. (1983) Hepatozelluläre Arzneimittelreaktion unter Mebendazoltherapie bei Echinococcus cysticus. Z Gastroenterol 21: 324–329

    PubMed  CAS  Google Scholar 

  9. Arndorfer RC, Steff JJ, Dodds WJ, Linehan JH, Hogan WJ (1977) Improved infusion system for intraluminal oesophageal manometry. Gastroenterology 24: 7–23

    Google Scholar 

  10. Bar-Meir S, Greenen JE, Hogan WJ (1979) Biliary and pancreatic duct pressures measured by ERCP manometry in patients with suspected papillary stenosis. Dig Dis Sci 24: 209–213

    Article  PubMed  CAS  Google Scholar 

  11. Carr-Locke DL, Gregg JA (1981) Endoscopic manometry of pancreatic and biliary sphincter zones in man: basal results in healthy and volunteers. Dig Dis Sci 26: 7–15

    Article  PubMed  CAS  Google Scholar 

  12. Cotton PB (1972) Cannulation of the papilla of Vater by endoscopy and retrograde cholangiopancreatography (ERCP). Gut 13: 1014–1017

    Article  PubMed  CAS  Google Scholar 

  13. Csendes A, Kruse A, Funch-Jensen P (1979) Pressure measurements in the biliary tract and pancreatic duct system in controls and in patients with gallstones, previous cholecystectomy or common bile duct stones. Gastroenterology 77: 1203–1210

    PubMed  CAS  Google Scholar 

  14. Gennen JE, Hogan WJ, Dodds WJ, Stewart ET, Arndorfer RC (1980) Intraluminal pressure recording from the human sphincter of Oddi. Gastroenterology 78: 317–324

    Google Scholar 

  15. Hand BH (1973) Anatomy and function of the extrahepatic biliary system. Clin Gastroenterol 2: 3–29

    PubMed  CAS  Google Scholar 

  16. Hopton DS, Torrance HB (1967) Action of various drugs on the human common bile duct. Gut 8: 296–300

    Article  PubMed  CAS  Google Scholar 

  17. Kroesen G, Bodner E, Russe W (1978) Beeinflussung der intraoperativen Cholangiomanometrie durch Anästhesiemethoden. Anaesthesist 27: 21–24

    PubMed  CAS  Google Scholar 

  18. Ono K, Watanabe N, Suzuki K, Tsuchida H, Sugiyama Y, Abo M (1968) Bile flow mechanisms in man. Arch Surg 96: 869–874

    Article  PubMed  CAS  Google Scholar 

  19. Persson OA, Ekman M (1972) Effect of morphine CCK and sympathicomimetics on the sphincter of Oddi and intramural pressure on cat duodenum. Scand J Gastroenterol 7: 345–349

    Article  PubMed  CAS  Google Scholar 

  20. Staritz M, Ewe K, Meyer zum Büschenfelde K-H (1983) Endoskopische Papillen- and Gallenwegsmanometrie bei Patienten mit Cholezystolithiasis. Verh Dtsch Ges Inn Med 89: 837–840

    Google Scholar 

  21. Debongnie JC, Pauls C, Fievez M, Wibin E (1981) Prospective evaluation of the diagnostic accuracy of liver. Ultrasonography Gut 22: 130–135

    CAS  Google Scholar 

  22. Foster KJ, Dewbury KG, Griffith AH, Wright R (1980) Br J Radiol 53: 440–442

    Article  PubMed  CAS  Google Scholar 

  23. Geissler M, Lorenz A, Zabel HJ, Lorenz WJ, Schlaps D, Zuna I (1982) A computerizid echographic data aquisitation and evaluation system for tissue characterization. Proc World Congr Med Phys Biomed Ing, Hamburg

    Google Scholar 

  24. Lachenbruch PA (1975) Discriminant analyses. Hafner Press, Macmillan Publ Co

    Google Scholar 

  25. Rettenmaier G (1977) Lebersonographie. Thieme Copythek. Thieme, Stuttgart

    Google Scholar 

  26. Carulli N, Manenti F, Gallo M, Salvioli GF (1971) Alcohol-drug interaction in man: alcohol and tolbutamide. Eur J Clin Invest 1: 421–424

    Article  PubMed  CAS  Google Scholar 

  27. Hoensch H, Hartmann F, Schomerus H, Bieck P, Dölle W (1979) Monooxygenase enzyme activity in alcoholics with varying degree of liver damage. Gut 20: 666–672

    Article  PubMed  CAS  Google Scholar 

  28. Hoensch H (1981) Fremdstoff-abbauendes Enzym-System der menschlichen Leber. Fortschr Med 99: 784–787

    PubMed  CAS  Google Scholar 

  29. Hoensch H (1984) Enzyminduktion der Leber durch chronischen Alkoholismus als Risikofaktor der Hepatotoxizität. Z Gastroenterol 22: 1–8

    PubMed  CAS  Google Scholar 

  30. Iber FL (1977) Drug metabolism in heavy consumers of ethyl alcohol. Clin Pharmacol Exp Ther 22: 735–742

    CAS  Google Scholar 

  31. Lieber CS (1973) Hepatic and metabolic effects of alcohol. Gastroenterology 65: 821–846

    PubMed  CAS  Google Scholar 

  32. Misra PS, Le Fevre A, Ischi H, Rubin E, Lieber C (1971) Increase in ethanol, meprobamate and pentobarbital metabolism after chronic ethanol administration in man and in rats. Am J Med 51: 346–352

    Article  PubMed  CAS  Google Scholar 

  33. Neuvonen PJ, Penttilä O, Roos O, Tirkonen J (1976) Effect of long term alcohol consumption on the half live of tetracycline and doxycycline in man. Int J Clin Pharmacol Biopharm 14: 303–307

    PubMed  CAS  Google Scholar 

  34. Ohnhaus EE, Gerber-Taras E, Park BK (1983) Enzyme-inducing drug combinations and their effects on liver microsomal enzyme activity in man. Eur J Clin Pharmacol 24: 247–250

    Article  PubMed  CAS  Google Scholar 

  35. Monna T (1982) Malotilate Symposium, World Congress of Gastroenterology, Stockholm 1982, Abstracts

    Google Scholar 

  36. Katoh M, Kitada M, Satoh T, Kitagawa H, Sugimoto T, Kasai T (1981) Further studies on the in vivo effect of Diisopropyl 1,3-dithiol-2-ylidenemalonate (NKK 105) on the liver microsomal drug oxidation system in rats. Biochem Pharmacol 30: 2759–2765

    Article  PubMed  CAS  Google Scholar 

  37. Voss B, Rauterberg J, Pott G et al. (1982) Nonparenchymal cells cultivated from explants of fibrotic liver resemble endothelial and smooth muscle cells from blood vessel walls. Hepatology 2: 19–28

    Article  PubMed  CAS  Google Scholar 

  38. Rohde H, Hahn E, Timpl R (1978) Radioimmunoassay for amino terminal procollagen peptide in liver diseases. Fresenius Z Analyt Chem 290: 151

    Article  CAS  Google Scholar 

  39. Ackermann W, Pott G, Voss B, Müller K-M, Gerlach U (1981) Serum concentration of procollagen-III-peptide in comparison with the serum activity of N-acetyl-ß-glucosaminidase for diagnosis of the activity of liver fibrosis in patients with chronic active liver disease. Clin Chim Acta 112: 365–369

    Article  PubMed  CAS  Google Scholar 

  40. Bührer M, Le Cotonnec JY, Wermeille M, Bircher J (1983) Auf dem Weg zu einer antifibrotischen Therapie der Leberzirrhose. Pilotstudien mit Malotilat. Jahrestagung der Schweizerischen Gesellschaft für Gastroenterologie 1983. Abstraktband

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Abt. Innere Med. II, Universität Ulm, Deutschland

    U. Junge

  2. Inst. Chirurgische Klinik, Universität Heidelberg, Deutschland

    P. Friedl

  3. Med. Klinik und, Poliklinik der Universität, Mainz, Deutschland

    M. Staritz, K. Ewe & K.-H. Meyer zum Büschenfelde

  4. Abt. für Gastroenterologie, Inst. für Nuklearmedizin des DKFZ und Med. Univ.-Klinik, Heidelberg, Deutschland

    U. Räth, I. Zuna, D. Schlaps, B. Limberg, A. Lorenz, G. van Kaick, W. J. Lorenz & B. Kommerell

  5. Abt. Allg. Innere Medizin, Univ. Essen, Deutschland

    H. Hoensch

  6. Med. Univ.-Klinik, Tübingen, Deutschland

    I. Schreyer

  7. Innere Abteilung, Marienkrankenhaus, Nordhorn, Deutschland

    G. Pott

  8. Institut für Arteriosklerosenforschung an, Universität Münster, Deutschland

    J. Rauterberg

  9. Medizinische Universitätsklinik, Münster, Deutschland

    G. Pott, M. Schneider, B. Högemann & U. Gerlach

  10. Bad Driburg, Fachklinik Rosenberg der LVA, Deutschland

    G. Eberhardt

Authors
  1. U. Junge
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. Friedl
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. M. Staritz
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. K. Ewe
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. K.-H. Meyer zum Büschenfelde
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. U. Räth
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. I. Zuna
    View author publications

    You can also search for this author in PubMed Google Scholar

  8. D. Schlaps
    View author publications

    You can also search for this author in PubMed Google Scholar

  9. B. Limberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  10. A. Lorenz
    View author publications

    You can also search for this author in PubMed Google Scholar

  11. G. van Kaick
    View author publications

    You can also search for this author in PubMed Google Scholar

  12. W. J. Lorenz
    View author publications

    You can also search for this author in PubMed Google Scholar

  13. B. Kommerell
    View author publications

    You can also search for this author in PubMed Google Scholar

  14. H. Hoensch
    View author publications

    You can also search for this author in PubMed Google Scholar

  15. I. Schreyer
    View author publications

    You can also search for this author in PubMed Google Scholar

  16. G. Pott
    View author publications

    You can also search for this author in PubMed Google Scholar

  17. J. Rauterberg
    View author publications

    You can also search for this author in PubMed Google Scholar

  18. M. Schneider
    View author publications

    You can also search for this author in PubMed Google Scholar

  19. B. Högemann
    View author publications

    You can also search for this author in PubMed Google Scholar

  20. G. Eberhardt
    View author publications

    You can also search for this author in PubMed Google Scholar

  21. U. Gerlach
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

Copyright information

© 1984 Springer-Verlag Berlin Heidelberg

About this paper

Cite this paper

Junge, U. et al. (1984). Hepatologie II. In: 90. Kongreß. Verhandlungen der Deutschen Gesellschaft für Innere Medizin, vol 90. J.F. Bergmann-Verlag, Munich. https://doi.org/10.1007/978-3-642-85457-6_30

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-85457-6_30

  • Publisher Name: J.F. Bergmann-Verlag, Munich

  • Print ISBN: 978-3-8070-0342-9

  • Online ISBN: 978-3-642-85457-6

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation