SpringerLink
Log in

Biliary Cancer

  • Chapter
Gastrointestinal Cancer

Part of the book series: Medical Radiology ((Med Radiol Radiat Oncol))

Abstract

Malignancies of the biliary tree are rare. These tumors cause a distinct combination of symptoms. According to this presentation and the possible treatment they can be divided by site as follows:

  • 1. Lesser intrahepatic bile ducts

  • 2. Right and left hepatic ducts

  • 3. The hilar region and common hepatic duct

  • 4. Gallbladder and cystic duct

  • 5. Common bile duct

  • 6. Region of the ampulla of Vater

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

eBook
USD 9.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  • Ackermann LV, Del Regato JA (1970) Cancer, diagnosis, treatment and prognosis. Mosby, St Louis

    Google Scholar 

  • Arminski T (1949) Primary carcinoma of the gall bladder. Cancer 2: 379

    Article  PubMed  CAS  Google Scholar 

  • Belmaric J (1973) Intrahepatic bile duct carcinoma and C. sinensis infection in Hong Kong. Cancer 31: 468–473

    Article  Google Scholar 

  • Beltz WR, Condon RE (1974) Primary carcinoma of the gall bladder. Ann Surg 180: 180–184

    Article  PubMed  CAS  Google Scholar 

  • Bergdahl L (1980) Gallbladder carcinoma first diagnosed at microscopic examination of gallbladder removed for presumed benign disease. Ann Surg 191: 19–22

    Article  PubMed  CAS  Google Scholar 

  • Black WC, Key CR, Carmany TB, Herman D (1977) Carcinoma of the gall bladder in a population of Southwestern American Indians. Cancer 39: 1267–1279

    Article  PubMed  CAS  Google Scholar 

  • Blumgart LH (1982) New perspectives and old problems in biliary surgery. Surg News 13: 1–4

    Google Scholar 

  • Blumgart LH, Benjamin IS, Hadjis NS, Bearley R (1984) Surgical approaches to cholangiocarcinoma at the confluence of hepatic ducts. Lancet 1: 66–70

    Google Scholar 

  • Broe PJ, Cameron JL (1981) The management of proximal biliary tract tumors. Adv Surg 15: 47–91

    PubMed  CAS  Google Scholar 

  • Buskirk SJ, Gunderson LL, Adson MA, Martinez A, May GR, McIlrath DC, Nagorney DM (1984) Analysis of failure following curative irradiation of gall bladder and extrahepatic bile duct carcinoma. Int J Radiat Bioi Oncol Phys 10: 2013–2023

    Article  CAS  Google Scholar 

  • Cahow CE (1979) Intrahepatic cholangiojejunostomy: a new simplified approach. Am J Surg 137: 443–448

    Article  PubMed  CAS  Google Scholar 

  • Cameron JL, Boe P, Zuidema GD (1982) Potential bile ducttumours: surgical management with Silastic biliary stents. Ann Surg 196: 412–419

    Article  PubMed  CAS  Google Scholar 

  • Collier NA, Carr D, Hemmingway A, Blumgart LH (1984) Preoperative diagnosis and its effect on the treatment of carcinoma of the gall bladder. Surg Gynecol Obstet 159: 465–470

    PubMed  CAS  Google Scholar 

  • Edmondson HA (1967) Tumors of the gall bladder and extrahepatic bile ducts. In: Atlas of tumour pathology, sect 7. Armed Forces Institute of Pathology, Washington DC, p 26

    Google Scholar 

  • Elias E (1976) A randomized trial of percutaneous transhepatic cholangiography with Chiba needle versus endoscopic retrograde cholangiography for bile duct visualization in, jaundice. Gastroenterology 71: 439–443

    PubMed  CAS  Google Scholar 

  • Ertan A, Kandilci U, Danisoglu V (1981) A comparison of percutaneous transhepatic cholangiographic and endoscopic retrograde cholangiopancreatography in postcholecystectomy jaundice. J Clin Gastroenterol 3: 67–72

    Article  PubMed  CAS  Google Scholar 

  • Evander A, Fredlund P, Hoevels J (1980) Evaluation of aggressive surgery for carcinoma of the extrahepatic bile ducts. Ann Surg 191: 23–29

    Article  PubMed  CAS  Google Scholar 

  • Fahim RB, McDonald JR, Richards JC, Ferris DO (1962) Carcinoma of the gall bladder: a study of modes of spread. Ann Surg 156: 114–124

    Article  PubMed  CAS  Google Scholar 

  • Flanigan DP (1977) Biliary carcinoma associated with biliary cysts. Cancer 40: 880–883

    Article  PubMed  CAS  Google Scholar 

  • Fletcher MS, Brinkley D, Dawson JL, Nunnerley H, Williams R (1983) Treatment of hilar carcinoma by bile drainage combined with internal radiotherapy using 192 iridium wire. Br J Surg 70: 733–735

    Article  Google Scholar 

  • Fogel TD, Weissberg JB (1984) The role of radiation therapy in carcinoma of the extrahepatic bile ducts. Int J Radiat Oncol Bioi Phys 10: 2251–2258

    Article  CAS  Google Scholar 

  • Fortner JG (1955) The experimental induction of primary carcinoma of the gall bladder. Cancer 8: 689–700

    Article  PubMed  CAS  Google Scholar 

  • Fortner JG (1958) An appraisal of the pathogenesis of primary carcinoma of the extrahepatic biliary tract. Surgery 43: 563–571

    PubMed  CAS  Google Scholar 

  • George PA (1983) Cancer of the bile ducts. In: Gazet JC (ed) Carcinoma of the liver, biliary tract and pancreas. Arnold, London, pp 104–151

    Google Scholar 

  • George PA, Brown C, Foley RTE (1981) Carcinoma of the hepatic duct function. Br J Surg 68: 14–18

    Article  PubMed  CAS  Google Scholar 

  • Gupta S, Udupa KN, Gupta S (1980) Primary carcinoma of the gall bladder: A review of 328 cases. J Surg Oncol 14: 35–44

    Article  PubMed  CAS  Google Scholar 

  • Haenszel W, Kurihara M (1968) Studies of Japanese migrants. I. Mortality from cancer and other diseases among Japanese in the United States. INC! 40: 43–68

    CAS  Google Scholar 

  • Hart J, Modan B, Shani M (1971) Cholelithiasis in the aetiology of gall bladder neoplasms. Lancet 1: 1151–1153

    Article  PubMed  CAS  Google Scholar 

  • Haskell CM (1980) Cancer of the liver: In: Haskell CM (ed) Cancer treatment. Saunders, Philadelphia, pp 319–357

    Google Scholar 

  • Herskovic AM, Engler MJ, Noell KT (1985) Radical radiotherapy for bile duct carcinoma. Endocuriether Hyperthermia Oncoll: 119–124

    Google Scholar 

  • Hopfan S, Watson R (1978) Porta hepatis irradiation. Int J Radiat Oncol Bioi Phys 4: 333–336

    CAS  Google Scholar 

  • Huibregtse K (1984) Endoscopic insertion of stents through malignant and benign biliary strictures. In: Yap SM, v. d. Sluis SF, Lamers CBHW (eds.) Recent advances in diagnostic and therapeutic endoscopy. Mur Kostverloren, Aalsmeer, pp 57–63

    Google Scholar 

  • Ingis DA, Farmer RG (1975) Adenocarcinoma of the bile ducts. Relationship of anatomic location to clinical features. Am J Dig Dis 20: 253–261

    Article  Google Scholar 

  • Inouye AA, Whelan TJ (1978) Carcinoma of the extrahepatic bile ducts. Am J Surg 136: 90–95

    Article  PubMed  CAS  Google Scholar 

  • Itami J, Saegusa K, Tsuchiya Y, Mamiya T, Miyoshi T, Ohto M, Arimizu N (1986) Intrakavitare High-dose-rate-Afterloading- Bestrahlung beim inoperablen malignen Gallengangsverschlulß. Strahlenther Onko1162: 105–110

    CAS  Google Scholar 

  • Jain S, Long RG, Scott 1, Dick R, Sherlock S (1977) Percutaneous transhepatic cholangiography using the “Chiba” needle - 80 cases. Br 1 Radiol 50: 175–180

    Article  PubMed  CAS  Google Scholar 

  • J0hnson OW, Safai C, Goffinet DR (1985) Malignant obstructive jaundice: treatment with external-beam and intracavitary radiotherapy. Int 1 Radiat Oncol Bioi Phys 11: 411–416

    Article  PubMed  CAS  Google Scholar 

  • Karani 1, Fletcher M, Brinkley 0, Dawson JL, Williams R, Nunnerley H (1985) Internal biliary drainage and local radiotherapy with iridium-192 wire in treatment of hilar cholangiocarcinoma. Clin Radiol 36: 603–606

    Article  PubMed  CAS  Google Scholar 

  • Klatskin G (1965) Adenocarcinoma of the hepatic duct at its bifurcation within the porta hepatis. Am 1 Med 38: 241–256

    Article  Google Scholar 

  • Koga A, Yamauchi S, Izumi Y, Hamanaka N (1985) Ultrasonigraphic detection of early and curable carcinoma of the gallbladder. Br 1 Surg 72: 728–730

    Article  PubMed  CAS  Google Scholar 

  • Koo 1, Wong 1, Cheng FC, Ong GB (1981) Carcinoma of the gall bladder. Br 1 Surg 68: 161–165

    Article  PubMed  CAS  Google Scholar 

  • Kopelson G, Harisiadis L, Tretter P, Chang CH (1977) The role of radiation therapy in cancer of the extra-hepatic biliary system. Int 1 Radiat Oncol Bioi Phys 2: 883–894

    Article  CAS  Google Scholar 

  • Kozuka S, Tsubone M, Hachisuka K (1984) Evolution of carcinoma in the extrahepatic bile ducts. Cancer 54: 65–72

    Article  PubMed  CAS  Google Scholar 

  • Krain LS (1972) Gall bladder and extrahepatic bile duct carcinoma. Geriatrics 27: 111–117

    PubMed  CAS  Google Scholar 

  • Kutzner 1, Klose K, Keller E (1985) Palliative Gallengangsbestrahlung. Strahlentherapie 161: 669–672

    PubMed  CAS  Google Scholar 

  • Laméris JS, Obertop H, leekel J (1985) Biliary drainage by ultrasound guided puncture of the left hepatic duct. Clin Radiol 36: 269–274

    Article  PubMed  Google Scholar 

  • Lameris JS, Stoker J, Dees J, Nix GAJJ, v. Blankenstein M, Jeekell (1987) Non-surgical palliative treatment of patients with malignant biliary obstruction - The place of endoscopic and percutaneous drainage. Clin Radiol 38: 603–608

    Article  Google Scholar 

  • Launois B, Campion lP, Brissot P (1979) Carcinoma of the hepatic hilus. Ann Surg 190: 151–157

    Article  PubMed  CAS  Google Scholar 

  • Lee TG, Henderson SC, Ehrlich R (1977) Ultrasound diagnosis of common bile duct dilatation. Radiology 124: 793–797

    PubMed  CAS  Google Scholar 

  • Lees CD, Zapolanski A, Cooperman AM (1980) Carcinoma of the bile ducts. Surg Gynecol Obstet 151: 193–198

    PubMed  CAS  Google Scholar 

  • Litwin MS (1967) Primary carcinoma of the gall bladder; review of 28 cases. Arch Surg 95: 236–240

    Article  PubMed  CAS  Google Scholar 

  • Longmire WP (1976) Tumors of the extrahepatic biliary radicals. In: Hickey RC (ed) Current problems in cancer. Year Book Medical Publishers, Chicago, p 1

    Google Scholar 

  • Longmire WP, McArthur MS, Bastounis EA (1973) Carcinoma of the extrahepatic biliary tract. Ann Surg 178: 333–345

    Article  PubMed  CAS  Google Scholar 

  • Lowenfels AB (1978) Does bile promote extra-colonic cancer? Lancet 2: 239–241

    Article  PubMed  CAS  Google Scholar 

  • Lowenfels AB, Lindström CG, Conway Ml, Hasting PR (1985) Gall stones and risk of gall bladder cancer. INCI 75:77–80

    CAS  Google Scholar 

  • Matzen P, Haubek A, Holst-Christensen J, Lejerstofte J, Juhl E (1981) Accuracy of direct cholangiography by endoscopic or transhepatic route in jaundice - a prospective study. Gastroenterology 81: 237–241

    PubMed  CAS  Google Scholar 

  • McPherson GAD, Benjamin IS, Habib NA, Bowley NB, Blumgart LH (1982) Percutaneous transhepatic drainage in obstructive jaundice: advantages and problems. Br 1 Surg 69: 261–264

    Article  PubMed  CAS  Google Scholar 

  • Mittal B, Deutsch M, Iwatsuki S (1985) Primary cancers of extrahepatic biliary passages. Int 1 Radiat Oncol Bioi Phys 11: 849–854

    Article  PubMed  CAS  Google Scholar 

  • Moertel CG (1982) The gall bladder: extrahepatic bile ducts. In: Holland JF, Fre E III (eds) Cancer medicine. Lea and Febiger, Philadelphia, pp 1785–1790

    Google Scholar 

  • Molt P, Hopfan S, Watson RC, Botet IF, Brennan MF (1986) Intraluminal radiation therapy in the management of malignant biliary obstruction. Cancer 57: 536–544

    Article  PubMed  CAS  Google Scholar 

  • Morner F, Ardiet 1M, Bret P, Gerard lP (1984) Radiotherapy of high bile duct carcinoma using intracatheter iridium 192 wire. Cancer 54: 2069–2073

    Article  Google Scholar 

  • Neill RH, de Weese RS (1973) Primary carcinoma of the gall bladder. Am J Surg 125: 726–729

    Article  Google Scholar 

  • Nevin lE, Moran n, Kay S, King R (1976) Carcinoma of the gall bladder. Cancer 37: 141–148

    Article  Google Scholar 

  • Ogoshi K, Niwa M (1977) The diagnostic evaluation of ERCP in pancreatic and biliary carcinoma. Gastroenterol Jpn 12: 218–223

    PubMed  CAS  Google Scholar 

  • Okuda K, Tanikawa K, Emura T, Kuratomi S, **nouchi S, Urabe K, Sumikoshi T, etal . (1974) Nonsurgical, percutaneous transhepatic cholangiography - diagnostic significance in medical problems of the liver. Dig Dis 19: 21–26

    Article  CAS  Google Scholar 

  • Oswalt CE, Cruz AB (1977) Effectiveness of chemotherapy in addition to surgery in treating carcinoma of the gall bladder. Rev Surg 34: 436–438

    PubMed  CAS  Google Scholar 

  • Ottow RT, August DA, Sugarbaker PH (1985) Treatment of proximal biliary tract carcinoma: An overview of techniques and results. Surgery 97: 251–262

    PubMed  CAS  Google Scholar 

  • Palla L, Rizzatto G, Pozzi-Mucelli RS, Bazzocchi M (1980) Grey-scale ultrasonography in the evaluation of carcinoma of the gall bladder. Br 1 Radiol 53: 662–667

    Article  Google Scholar 

  • Passariello R, Pavone P, Simonetti G, Modini C, Lasagni RP, Mannella P, Gazzaniga GM, etal . (1985) Percutaneous biliary drainage in neoplastic jaundice. Acta Radiol [Diagn] (Stockh) 26: 681–688

    CAS  Google Scholar 

  • Philip 1, Hagenmüller F, Manegold K, Szepesi S, Classen M (1984) Endoskopische, intraduktuale Strahlentherapie hochsitzender Gallengangskarzinome. Dtsch Med Wochenschr 109: 422–426

    Article  Google Scholar 

  • Piehler 1M, Crichbow RW (1978) Primary carcinoma of the gall bladder (collective reviews). Surg Gynecol Obstet 147: 929–942

    Google Scholar 

  • Pipelich MY, Lambert PM (1978) Radiotherapy of carcinomas of the biliary extrahepatic system. Radiology 127: 767–770

    Google Scholar 

  • Polk HC (1966) Carcinoma of the calcified gall bladder. Gastroenterology 50: 582–585

    PubMed  Google Scholar 

  • Richter JM, Silverstein MD, Shapiro R (1983) Suspected obstructive jaundice: A decision analysis of diagnostic strategies. Ann Intern Med 99: 46–51

    CAS  Google Scholar 

  • Ritchie JR, Allan RN, Macartney J (1974) Biliary tract carcinoma associated with ulcerative colitis. Q 1 Med 170: 263–279

    Google Scholar 

  • Ross AP, Bruasch lW, Warren KW (1973) Carcinoma of the proximal bile ducts. Surg Gynecol Obstet 136: 923–928

    PubMed  CAS  Google Scholar 

  • Segi M (1969) Cancer mortality for selected sites in 24 countries, no 5. Department of Public Health, Tohuku University School of Medicine, Sendas

    Google Scholar 

  • Shieh Cl, Dunn E, Standard lE (1981) Primary carcinoma of the gall bladder. Cancer 47: 996–1004

    Article  Google Scholar 

  • Smoron GL (1977) Radiation therapy of gall bladder and biliary tract. Cancer 40: 1422–1424

    Article  Google Scholar 

  • Strauch GO (1960) Primary carcinoma of the gall bladder. Presentation of seventy cases from the Rode Island Hospital and a cumulative review of the last ten years of the American literature. Surgery 47: 368–383

    PubMed  CAS  Google Scholar 

  • Tasaka K, Watanabe H, Enjoji M (1975) Carcinomas of the pancreas, gall bladder, extrahepatic bile ducts and duodenal papilla. A statistical observation of 137 autopsy cases. Fukuoka Acta Med 66: 486–499

    PubMed  CAS  Google Scholar 

  • Terblanche J (1976) Is carcinoma of the main hepatic duct junction an indication for liver transplantation or palliative surgery? Surgery 79: 127–128

    PubMed  CAS  Google Scholar 

  • Terblanche J, Saunders SJ, Louw JH (1972) Prolonged palliation in carcinoma of the main hepatic duct junction. Surgery 71: 720–731

    Google Scholar 

  • Todoroki T, Okamura T, Fukuo K, Nistimura A, Otsu H, Soto H, Iwasaki Y ( 1980 a) Gross appearance of main hepatic duct carcinoma and its prognosis. Surg Gynecol Obstet 150: 33–41

    PubMed  CAS  Google Scholar 

  • Todoroki T, Iwasaki Y, Okamura T, Nagoshi K, Asakura H, Nakano M, Inada T, etal . (1980b) Intraoperative radiotherapy for advanced carcinoma of the biliary systems. Cancer 46: 2179–2184

    Article  PubMed  CAS  Google Scholar 

  • Vaittinen E (1970) Carcinoma of the gall bladder, a study of 390 cases diagnosed in Finland 1953–1967. Ann Chir Gynaecol [suppI59l168: 7–81

    Google Scholar 

  • Vas W, Salem S (1981) Accuracy of sonography and transhepatic cholangiography in obstructive jaundice. J Can Assoc Radiol32: 111–113

    PubMed  CAS  Google Scholar 

  • von Eyben F, Hellekant C, Mattson W, Ljungquist U, Jonsson K (1980) Mitomycin C in advanced gall bladder carcinoma. Acta Radiol Oncol19: 81–84

    Article  Google Scholar 

  • Waterhouse J, Muir C, Correa P, Powell J (eds) (1976) Cancer incidence in five continents, vol 3. IARC, Lyon

    Google Scholar 

  • Whelton MJ, Petrelli W, George P (1969) Carcinoma at the junction of the main hepatic ducts. Q J Med 150: 211- 230

    Google Scholar 

  • Yeh HC (1979) Ultrasonography and computed tomography of carcinoma of the gall bladder. Radiology 133: 167–173

    PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Radiation Therapy, The Dr. Daniel den Hoe Cancer Center and Rotterdam Radio-Therapeutic Institute, P.O.Box 5201, 3008 AE, Rotterdam, The Netherlands

    J. H. Meerwaldt M.D., Ph. D.

Authors
  1. J. H. Meerwaldt M.D., Ph. D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Radiation Therapy, Medical College of Ohio, 3000 Arlington Avenue C.S. 10008, 43699, Toledo, OH, USA

    Ralph R. Dobelbower Jr. M. D., Ph. D., F.A.C.R. (Professor and Chairman, Professor of Neurological Surgery (Radiation Therapy) (Professor and Chairman, Professor of Neurological Surgery (Radiation Therapy)

Rights and permissions

Reprints and permissions

Copyright information

© 1990 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Meerwaldt, J.H. (1990). Biliary Cancer. In: Dobelbower, R.R. (eds) Gastrointestinal Cancer. Medical Radiology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-83657-2_8

Download citation

  • DOI: https://doi.org/10.1007/978-3-642-83657-2_8

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-83659-6

  • Online ISBN: 978-3-642-83657-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation