Abstract
The association between erectile dysfunction and decreased arterial flow deficiency to the corpus cavernosum was demonstrated for the first time by Leriche in 1923 [1]. He described a clinical syndrome characterized by claudication in the lower limbs, gluteal pain, and erectile dysfunction in a patient affected with an obstruction at the bifurcation of the iliac artery of an atherosclerotic nature. It was not until many years later that this association was correlated with an insufficient blood supply to the pelvic area and consequently to the corpus cavernosum. Since then much progress has been made in both the diagnostic and the therapeutic fields concerning erectile dysfunction, for example, with the discovery of va- soactive substances. When injected inside the corpus cavernosum of subjects without vascular alterations these provoke an erection similar to that occurring physiologically due to sexual excitement. These drugs, along with digital arteriographs, echo color Doppler, nocturnal penile tumescence test, and dynamic cavernosometry, have initiated a new era in the functional study of the vascularization of the penis and in the understanding of the pathophysiology of the erectile mechanism.
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Carmignani, G., De Stefani, S., Capone, M. (1996). Surgical Treatment. In: Ledda, A. (eds) Vascular Andrology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-79853-5_8
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DOI: https://doi.org/10.1007/978-3-642-79853-5_8
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