The Contribution of Brain Edema to Brain Swelling

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Intracranial Pressure VIII

Abstract

The deleterious effect of raised ICP following traumatic brain injury has been well recognized. However, it remains unclear whether the primary disruption of volume homeostasis and subsequent development of pressure is caused by brain edema or vascular engorgement. Primary traumatic swelling usually involves both hemispheres and in the more recent data obtained from the traumatic coma data bank (TCDB), of 595 patients studied, 31% of patients showed evidence of brain swelling [1]. Heretofore, it has not been possible to assess the contribution of increased water because of methodological problems in volume assessment. However, the recent introduction of magnetic resonance (MR) methods and the inherent sensitivity of changes in relaxation time to brain water has led to the development of quantitative methods capable of determining spatial distribution of edema non-invasively [2, 3].

This work was supported by a NIDRR Grant No. H133B80029

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References

  1. Eisenberg H, Gary H, Jane J, et al. (1988) CT scan findings in a series of 595 patients with severe closed head injury: A report from the NIH traumatic coma data bank. Annual Meeting of the American Association of Neurological Surgeons Toronto, Ontario April 24–28

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  2. Fatouros P, Marmarou A, Kraft K, et al. (1991) In vivo brain water determination of Tl measurements: Effect of total water content hydration fraction and field strength. Magn Reson Med 17:402–413

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  3. Marmarou A, Fatouros P, Ward, et al. (1990) In Vivo measurement of brain water by MRI. Brain Edema VIII. JH Reulen, A Baethmann, J Fenstermacher, A Marmarou, M Spatz (eds) Acta Neurochirurgica supplementum 51:261–262, by Springer-Verlag

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© 1993 Springer-Verlag Berlin Heidelberg

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Marmarou, A. et al. (1993). The Contribution of Brain Edema to Brain Swelling. In: Avezaat, C.J.J., van Eijndhoven, J.H.M., Maas, A.I.R., Tans, J.T.J. (eds) Intracranial Pressure VIII. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-77789-9_114

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  • DOI: https://doi.org/10.1007/978-3-642-77789-9_114

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-77791-2

  • Online ISBN: 978-3-642-77789-9

  • eBook Packages: Springer Book Archive

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