Abstract
Chemists are continuously confronted with the challenge of classifying and accurately assessing the complexity elements presented by natural products, and these elements are often assigned familiar categories such as topological, stereochemical, and size complexities. An interesting additional element of complexity involves the fusion of well-known functional groups into larger entities, with the individual constituents in communication by a combination of resonance and inductive effects. α,β-Unsaturated carbonyls (carbonyl + alkene) and enamines (amine + alkene) may be the simplest examples of such functionality.
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Herzon, S.B. (2012). The Kinamycins. In: Li, J., Corey, E. (eds) Total Synthesis of Natural Products. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-642-34065-9_3
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DOI: https://doi.org/10.1007/978-3-642-34065-9_3
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