Abstract
Cutaneous melanoma is rare in children, but its incidence increases in adolescents. The pathogenesis of melanoma is multifactorial, making prevention important in its clinical history. The clinical management of pediatric patients with melanoma is still challenging because it is difficult to diagnose. Few studies have specifically addressed the topic of melanoma in children. Though melanoma in young patients may have particular biological characteristics, available data seem to suggest that its clinical history is similar to that of adult melanoma. The benefits of new therapies for adult melanoma have not been reflected in younger patients. There is no standard treatment for children with this tumor, and it is difficult for them to access clinical trials. More efforts (including international collaboration between pediatric and adult melanoma groups) are needed to facilitate the transfer of potentially effective new agents from adults to children and adolescents and to improve research programs dedicated to young melanoma patients.
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Indini, A., Pappo, A.S., Eigentler, T.K., Collini, P., Ferrari, A. (2022). Cutaneous Melanoma. In: Schneider, D.T., Brecht, I.B., Olson, T.A., Ferrari, A. (eds) Rare Tumors in Children and Adolescents. Pediatric Oncology. Springer, Cham. https://doi.org/10.1007/978-3-030-92071-5_40
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