Abstract
Cell-mediated immunity is a significant aspect of the host response to herpes simplex virus (HSV) infection. Several investigators have shown that adoptive transfer of immune T lymphocytes will protect mice against virus challenge (1,2,3). More recently, in vitro studies have shown that draining lymph node (4,5) or spleen cells (6) from virus-sensitized hosts were specifically cytotoxic for HSV-infected cells. Substantial levels of lysis usually were not seen, however, unless the effector cells, identified as T lymphocytes (6,7) first had experienced some form of experimental manipulation such as incubation in vitro for a number of days.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Ennis, F.A. Infect Immun 7 (1973) 898.
Oakes, J.E. Infect Immun 12 (1975) 166.
Rager-Zisman, B.; Allison, A.C. J Immunol 116 (1976) 35.
Hay, K.A.; Lausch, R.N. Int J Cancer 23 (1979) 337.
Pfizenmaier, K. et al. Immunology 119 (1977) 939.
Lawman, M.J.P. et al. Infect Immun 27 (1980) 133.
Pfizenmaier, K. et al. Nature 265 (1977) 630.
Herberman, R.B. et al. Int J Cancer 16 (1975) 216.
Kiessling, R. et al. Eur J Immunol 5 (1975) 112.
Herberman, R.B.; Holden, H.T. Adv Cancer Res 27 (1978) 305.
Nahmias, A.J. et al. Proc Soc Exp Biol Med 134 (1970) 1065.
McCormick, K.J.; Trentin, J.J. Prog Exp Tumor Res 23 (1979) 13.
Lausch, R.H.; Rapp, F. Int J Cancer 7 (1971) 322.
Duff, R.; Rapp, F. J Virol 12 (1973) 209.
Rapp, F.; Duff, R. Cancer Res 33 (1973) 1527.
Laux, D.; Lausch, R.N. J Immunol 112 (1974) 1900.
Datta, S.K. et al. Int J Cancer 23 (1979) 728.
Shore, S.L. et al. Nature 251 (1974) 350.
Rager-Zisman, B.; Bloom, B.R. Nature 251 (1974) 542.
Gee, S.R. et al. J Immunol 123 (1979) 2618.
Herberman, R.B. et al. Immunol Rev 44 (1979) 43.
Santoli, D. et al. J Immunol 121 (1978) 526.
Santoli, D. et al. J Immunol 121 (1978) 532.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1981 Plenum Press, New York
About this chapter
Cite this chapter
Lausch, R.N., Patton, N., Walker, D. (1981). Natural Cytotoxicity by Hamster Lymphoid Cells for Virus-Infected and Transformed Cells. In: Wayne Streilein, J., Hart, D.A., Stein-Streilein, J., Duncan, W.R., Billingham, R.E. (eds) Hamster Immune Responses in Infectious and Oncologic Diseases. Advances in Experimental Medicine and Biology, vol 134. Springer, Boston, MA. https://doi.org/10.1007/978-1-4757-0495-2_13
Download citation
DOI: https://doi.org/10.1007/978-1-4757-0495-2_13
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4757-0497-6
Online ISBN: 978-1-4757-0495-2
eBook Packages: Springer Book Archive