Transglucosylation Catalysed by the Exo-ß-Glucanase of Candida Albicans

  • Chapter
Candida and Candidamycosis

Abstract

The β-1,3/1,6-glucan that constitutes 70% of the cell wall of Candida albicans 1 is qualitatively similar to the glucan of Saccharomyces cerevisiae but it contains higher proportions of branch points (7%) and β-1,6 linkages (43–50%)2.Cabib at al. 3 have reviewed the current understanding of the synthesis of the call wall. Linear chains of β-1,3 glucan are synthesized by a UDP-glucose synthetase located in the plasma membrane but nothing is known about the formation of β-1,6 oligosaccharide chains, branching or cross linking to other polymers. In this paper we describe a rapid transglucosylation reaction catalyzed by an exo-β-glucanase from C.albicans.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Subscribe and save

Springer+ Basic
EUR 32.99 /Month
  • Get 10 units per month
  • Download Article/Chapter or Ebook
  • 1 Unit = 1 Article or 1 Chapter
  • Cancel anytime
Subscribe now

Buy Now

eBook
USD 9.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free ship** worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Similar content being viewed by others

References

  1. P.A.Sullivan, Y.Y.Chiew, C.Molloy, M.D.Templeton and M.G.Shepherd, Canad.J.Microbiol., 29: 1514 (1983).

    Article  CAS  Google Scholar 

  2. P.K.Gopal, M.G.Shepherd and P.A.Sullivan, J. Gen. Microbiol., 130: 3295 (1984).

    CAS  Google Scholar 

  3. E.Cabib, B.Bowers, A.Sburleti and S.J.Silverman, Microbiol. Sci. 5: 370 (1988).

    PubMed  CAS  Google Scholar 

  4. S.P. Ram, L.K. Romana, M.G. Shepherd and P.A. Sullivan, J. Gen. Microbiol., 130: 1227 (1984).

    PubMed  CAS  Google Scholar 

  5. S.P.Ram, K.H.Hynes, S.P.Romana, M.G.Shepherd and P.A.Sullivan, Life Science Advances - Biochemistry 7 (in press) (1988).

    Google Scholar 

  6. M.Molina, R.Cenamor and C.Nombela, J. Gen. Microbiol., 113: 609 (1987).

    Google Scholar 

  7. C.Nombela, M.Molina, R.Cenamor and M.Sanchez, Microbiol Sci., 5: 328 (1988).

    Google Scholar 

  8. A.G.Dickerson and R.C.F.Baker, J.Gen. Microbiol., 112: 67 (1979).

    Google Scholar 

  9. K.Nisizawa and Y.Hashimoto, in: “The Carbohydrates: Chemistry and Biochemistry”, W.W. Pigman and D. Horton, eds., pp. 241–300, Academic Press, New York (1970).

    Google Scholar 

  10. K.G.Nilsson, Tibtech., 6: 256 (1988).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 1991 Plenum Press, New York

About this chapter

Cite this chapter

Sullivan, P.A., Emerson, G.W., Broughton, M.J., Stubbs, H.J. (1991). Transglucosylation Catalysed by the Exo-ß-Glucanase of Candida Albicans . In: Tümbay, E., Seeliger, H.P.R., Anǧ, Ö. (eds) Candida and Candidamycosis. Federation of European Microbiological Societies Symposium Series, vol 50. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5910-4_5

Download citation

  • DOI: https://doi.org/10.1007/978-1-4684-5910-4_5

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5912-8

  • Online ISBN: 978-1-4684-5910-4

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Navigation