Abstract
The fundamental problem in the treatment of Parkinson’s disease is the appearance of motor fluctuations after long-term drug therapy (long-term L-dopa treatment syndrome, LTS, Marsden and Parkes, 1976). The clinical manifestations of LTS are complex, consisting of a varying association of akinetic symptoms and dyskinesias whose pathogenesis has still not been clarified.
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© 1991 Plenum Press, New York
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Caraceni, T. et al. (1991). Treatment of Motor Fluctuations in Parkinson’s Disease: Controlled Release Preparations. In: Bernardi, G., Carpenter, M.B., Di Chiara, G., Morelli, M., Stanzione, P. (eds) The Basal Ganglia III. Advances in Behavioral Biology, vol 39. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5871-8_74
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DOI: https://doi.org/10.1007/978-1-4684-5871-8_74
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