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Molecular Properties of Voltage-Sensitive Calcium Channels

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Calcium Protein Signaling

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 255))

Abstract

Voltage sensitive calcium channels participate in action potential generation in electrically excitable cells and constitute an essential link between transient changes in membrane potential and a variety of cellular responses including secretion of neurotransmitters and hormones, initiation of contraction in cardiac and smooth muscle, and activation of second messenger responses in many cell types. Electrophysiological measurements have established the existence of multiple classes of calcium channels.1–4 Although work on many cell systems has contributed to current understanding of calcium channel function, the molecular properties of the channel have been investigated most thoroughly in skeletal muscle which has a particularly high density of calcium channels. This chapter will therefore focus primarily on skeletal muscle calcium channels.

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Author information

Authors and Affiliations

  1. Department of Pharmacology, SJ-30, University of Washington, Seattle, WA, 98195, USA

    William A. Catterall, Michael J. Seagar, Masami Takahashi & Kazuo Nunoki

Authors
  1. William A. Catterall
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  2. Michael J. Seagar
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  3. Masami Takahashi
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  4. Kazuo Nunoki
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Editor information

Editors and Affiliations

  1. Nagoya University, Nagoya, Japan

    H. Hidaka

  2. Swiss Federal Institute of Technology, Zurich, Switzerland

    E. Carafoli

  3. Baylor College of Medicine, Houston, Texas, USA

    A. R. Means

  4. Mie University School of Medicine, Mie, Japan

    T. Tanaka

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© 1989 Plenum Press, New York

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Catterall, W.A., Seagar, M.J., Takahashi, M., Nunoki, K. (1989). Molecular Properties of Voltage-Sensitive Calcium Channels. In: Hidaka, H., Carafoli, E., Means, A.R., Tanaka, T. (eds) Calcium Protein Signaling. Advances in Experimental Medicine and Biology, vol 255. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-5679-0_11

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  • DOI: https://doi.org/10.1007/978-1-4684-5679-0_11

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4684-5681-3

  • Online ISBN: 978-1-4684-5679-0

  • eBook Packages: Springer Book Archive

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