Sialic Acid in Normal and Dry Eye Tear Fluid

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Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3

Part of the book series: Advances in Experimental Medicine and Biology ((AEMB,volume 506))

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Abstract

Mucin is a particularly important component in the pathogenesis of dry eye, because it is the main constituent of the mucus layer and contributes to tear film stability and viscosity.1 Although several methods can detect mucin in tear film, mucin measurement is difficult because of its high molecular weight. Based on the fact that mucin is composed of many glycoproteins,2 the periodic acid-Schiff (PAS) method has been used to measure it in the stomach and small intestine.

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© 2002 Kluwer Academic/Plenum Publishers

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Nakamura, Y., Yokoi, N., Tokushige, H., Kinoshita, S. (2002). Sialic Acid in Normal and Dry Eye Tear Fluid. In: Sullivan, D.A., Stern, M.E., Tsubota, K., Dartt, D.A., Sullivan, R.M., Bromberg, B.B. (eds) Lacrimal Gland, Tear Film, and Dry Eye Syndromes 3. Advances in Experimental Medicine and Biology, vol 506. Springer, Boston, MA. https://doi.org/10.1007/978-1-4615-0717-8_50

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  • DOI: https://doi.org/10.1007/978-1-4615-0717-8_50

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4613-5208-2

  • Online ISBN: 978-1-4615-0717-8

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