An Advanced DSS for Classification of Multiple-Sclerosis Lesions in MR Images

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Emerging Trends in Computing, Informatics, Systems Sciences, and Engineering

Part of the book series: Lecture Notes in Electrical Engineering ((LNEE,volume 151))

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Abstract

The use of Magnetic Resonance as a supporting tool in the diagnosis and monitoring of Multiple Sclerosis and in the assessment of treatment effects requires the accurate classification of cerebral white matter lesions. In order to support neuroradiologists in this task, this paper presents an advanced Decision Support System devised to: (i) encode the expert’s medical knowledge in terms of linguistic variables, linguistic values, and fuzzy rules; (ii) implement a fuzzy inference technique able to best fit the expert’s decision-making process to identify MS lesions; (iii) employ an adaptive fuzzy technique to tune the shapes of the membership functions for each linguistic variable involved in the rules. The performance of the DSS is quantitatively evaluated on 120 patients affected by MS.

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References

  1. Zadeh L (1965) Fuzzysets. Inform Control 8:338–353

    Article  MathSciNet  MATH  Google Scholar 

  2. Estevez J, Alayon S, Moreno L, Sigut J, Aguilar R (2005) Cytological image analysis with a genetic fuzzy finite state machine. J Comput Methods Programs Biomed 80(11):3–15

    Article  MathSciNet  Google Scholar 

  3. Suryanarayanan S, Reddy NP, Canilang EP (1995) A fuzzy logic diagnosis system for classification of pharyngeal dysphagia. Int J Biomed Comput 38:207–215

    Article  Google Scholar 

  4. Anuradha B, Reddy V (2008) Cardiac arrhythmia classification using fuzzy classifiers. J Theor Appl Inf Technol 4(4):353–359

    Google Scholar 

  5. Gonzalez A, Perez R, Valenzuela A (1995) Diagnosis of myocardial infarction through fuzzy learning techniques. In: Proceedings of the sixth international fuzzy systems association world congress (IFSA’95), pp 273–276

    Google Scholar 

  6. Filippi M, Rovaris M, Campi A, Pereira C, Comi G (1996) Semi-automated thresholding technique for measuring lesion volumes in multiple sclerosis: effects of the change of the threshold on the computed lesion loads. Acta Neurol Scand 93:30–34

    Article  Google Scholar 

  7. Akselrod-Ballin A, Galun M, Gomori JM, Filippi M, Valsasina P, Basri R, Brandt A (2009) Automatic segmentation and classification of multiple sclerosis in multichannel MRI. IEEE Trans Biomed Eng 56:2461–2469

    Article  Google Scholar 

  8. Alfano B, Brunetti A, Arpaia M, Ciarmiello A, Covelli EM, Salvatore M (1995) Multiparametric display of Shin-echo data from MR studies of brain. J Magn Reson Imaging 5:217–225

    Article  Google Scholar 

  9. Freifeld O, Greenspan H, Goldberger J (2009) Multiple sclerosis lesion detection using constrained GMM and curve evolution. Int J Biomed Imaging Article ID 715124 13:13

    Google Scholar 

  10. Khayati R, Vafadust M, Towhidkhah F, Nabavi M (2008) Fully automatic segmentation of multiple sclerosis lesions in brain MR FLAIR images using adaptive mixtures method and Markov random field model. Comput Biol Med 38:379–390

    Article  Google Scholar 

  11. Wels M, Huber M, Hornegger J (2008) Fully automated segmentation of multiple sclerosis lesions in multispectral MRI. Pattern Recognit Image Anal 18:347–350

    Article  Google Scholar 

  12. Alfano B, Brunetti A, Larobina M, Quarantelli M, Tedeschi E, Ciarmiello A, Covelli EM, Salvatore M (2000) Automated segmentation and measurement of global white matter lesion volume in patients with multiple sclerosis. J Magn Reson Imaging 12:799–807

    Article  Google Scholar 

  13. Russo F, Ramponi G (1995) A fuzzy operator for the enhancement of blurred and noisy images. IEEE Trans Image Process 4:1169–1174

    Article  Google Scholar 

  14. Gilesa R (1975) Lukasiewicz logic and fuzzy set theory. Int J Man Mach Stud 8(3):313–327

    Article  Google Scholar 

  15. Storn R, Price K (1997) Differential evolution—a simple and efficient heuristic for global optimization over continuous spaces. J Global Optim 11(4):341–359

    Article  MathSciNet  MATH  Google Scholar 

  16. Nobakhti A, Wang H (2008) A simple self-adaptive differential evolution algorithm with application on the ALSTOM gasifier. Appl Soft Comput 8:350–370

    Article  Google Scholar 

  17. Das S, Konar A, Chakraborty UK, Abraham A (2009) Differential evolution with a neighborhood-based mutation operator: a comparative study. IEEE Trans Evol Comput 13(3):526–553

    Article  Google Scholar 

  18. Hall M, Frank E, Holmes G, Pfahringer B, Reutemann P, Witten IH (2009) The WEKA data mining software: an update. SIGKDD Explorations 11(1):1–11

    Google Scholar 

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Correspondence to I. De Falco .

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De Falco, I., Esposito, M., De Pietro, G. (2013). An Advanced DSS for Classification of Multiple-Sclerosis Lesions in MR Images. In: Sobh, T., Elleithy, K. (eds) Emerging Trends in Computing, Informatics, Systems Sciences, and Engineering. Lecture Notes in Electrical Engineering, vol 151. Springer, New York, NY. https://doi.org/10.1007/978-1-4614-3558-7_32

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  • DOI: https://doi.org/10.1007/978-1-4614-3558-7_32

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