Surgical Treatment of Malignant Tumors of the Oral Cavity

  • Chapter
Oral Oncology

Part of the book series: Developments in Oncology ((DION,volume 20))

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Abstract

Squamous cell carcinomas make up the great majority of malignant tumors of the oral cavity. There is no unanimity as to the preferred method of treatment of oral cavity carcinoma. Depending on the policy of the institution, the primary cancer is treated either surgically or by radiotherapy. In locally advanced tumors the common practice is to apply radiation therapy as a pre- or postoperative adjuvant to surgical resection. Solid evidence to support the validity of this combined approach, however, is lacking. Although chemotherapy and to a minor degree immunotherapy have received much interest over the last decade, their role in the management of oral cancer has yet to be defined. Treatment of metastatic neck nodes has traditionally been by surgery, although elective irradiation of the neck has been recommended for the management of occult metastasis.

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References

  1. Shumrick DA. Carcinoma of the supraglottis and tongue treated by supraglottic laryngectomy and mandibular swing. Laryngoscope (79): 1443–1452, 1969.

    Article  PubMed  CAS  Google Scholar 

  2. Spiro RH, Gerold FP, Strong EW. Mandibular “swing” approach for oral and oropharyngeal tumors. Head & Neck Surg (3): 371–378, 1981.

    Article  CAS  Google Scholar 

  3. Westbury G. Carcinoma of the tongue. In Operative Surgery, Head and Neck, Rob C, Smith R (gen. eds), Wilson JSP (cons. ed). London: Butterworths, 1981, 664–671.

    Google Scholar 

  4. Ballantyne AJ. Current controversies in the management of cancer of the tongue and floor of the mouth. In Head and Neck Oncology, Controversies in Cancer Treatment, Kagan AR, Miles JW (eds). Boston: GK Hall, 1981, pp. 87–98.

    Google Scholar 

  5. Byers RM, Bland KI, Borlase B, Luna M. The prognostic and therapeutic value of frozen section determinations in the surgical treatment of squamous carcinoma of the head and neck. Am J Surg (136): 525–528, 1978.

    Article  PubMed  CAS  Google Scholar 

  6. Marchetta FC, Sako K, Murphy J. The periosteum of the mandible and intraoral carcinoma. Am J Surg (122): 711–713, 1971.

    Article  PubMed  CAS  Google Scholar 

  7. Carter RL, Tanner NSB, Clifford P, Shaw HJ. Direct bone invasion in squamous carcinomas of the head and neck: Pathological and clinical implications. Clin Otolaryngol (5): 107–116, 1980.

    Article  PubMed  CAS  Google Scholar 

  8. McGregor IA. Problems of reconstructive surgery of the oral cavity. J Laryngol Otol (91): 445–465, 1977.

    Article  PubMed  CAS  Google Scholar 

  9. Spiro RH, Strong EW. Discontinuous partial glossectomy and radical neck dissection in selected patients with epidermoid carcinoma of the mobile tongue. Amer J Surg (126): 544–546, 1973.

    Article  PubMed  CAS  Google Scholar 

  10. Nahum AM, Bone RC, Davidson TM. The case for elective prophylactic neck dissection. Laryngoscope (87): 588–599, 1977.

    PubMed  CAS  Google Scholar 

  11. Crile G. Excision of cancer of the head and neck, with special reference to the plan of dissection based upon 132 operations. JAMA (47): 1780–1786, 1906.

    Google Scholar 

  12. Martin H, Del Valle B, Ehrlich H, Cahan WG. Neck dissection. Cancer (4): 441–499, 1951.

    Article  PubMed  CAS  Google Scholar 

  13. Beahrs OH, Gossel JD, Hollingshead WH. Technique and surgical anatomy of radical neck dissection. Amer J Surg (90): 490–516, 1955.

    Article  PubMed  CAS  Google Scholar 

  14. Bocca E, Pignataro O. A conservation technique in radical neck dissection. Ann Otol (76): 975–987, 1967.

    CAS  Google Scholar 

  15. Bocca E, Pignataro O, Sasaki C. Functional neck dissection. Arch Otolaryngol (106): 524–527, 1980.

    PubMed  CAS  Google Scholar 

  16. Dayal VS, Da Silva AJ. Functional and radical neck dissection. Arch Otolaryngol (93): 413–415, 1971.

    PubMed  CAS  Google Scholar 

  17. Lingeman RE, Stephens R, Helmus C, Ulm J. Neck dissection: radical or conservative. Ann Otol (86): 737–744, 1977.

    CAS  Google Scholar 

  18. Chu W, Strawitz JG. Results in suprahyoid, modified radical, and standard radical neck dissections for metastatic squamous cell carcinoma: Recurrence and survival. Amer J Surg (136): 512–515, 1978.

    Article  PubMed  CAS  Google Scholar 

  19. Jesse RH, Ballantyne AJ, Larson D. Radical or modified neck dissection: A therapeutic dilemma. Amer J Surg (136): 516–519, 1978.

    Article  PubMed  CAS  Google Scholar 

  20. Molinari R, Chiesa F, Cantu G, Grandi C. Retrospective comparison of conservative and radical neck dissection in laryngeal cancer. Ann Otol (89): 578–581, 1980.

    CAS  Google Scholar 

  21. Noone RB, Bonner H, Raymond S, Brown AS, Graham WP, Lehr HB. Lymph node metastases in oral carcinoma. A correlation of histopathology with survival. Plast Reconstr Surg (53): 158–166, 1974.

    Article  PubMed  CAS  Google Scholar 

  22. Pointon RCS, Jelly GO. Block dissection of the neck for squamous cell carcinoma of the mouth and lips. Proc R Soc Med (69): 414–416, 1976.

    PubMed  CAS  Google Scholar 

  23. Kalnis IK, Leonard AG, Sako K, Razack MS, Shedd DP. Correlation between prognosis and degree of lymph node involvement in carcinoma of the oral cavity. Amer J Surg (134): 450–454, 1977.

    Article  Google Scholar 

  24. Micheau C, Sancho H, Gerard-Marchant R. Prognostic des adenopathies cervicales metas-tatiques en fonction des facteurs anatomopathologiques. Nuovo Arch Ital Otol VI (1): 5–14, 1978.

    Google Scholar 

  25. Zoller M, Goodman ML, Cummings CW. Guidelines for prognosis in head and neck cancer with nodal metastasis. Laryngoscope (88): 135–141, 1978.

    PubMed  CAS  Google Scholar 

  26. Cachin Y, Sancho-Garnier H, Micheau C, Marandas P. Nodal metastasis from carcinomas of the oropharynx. Otolaryngol Clin N Am (12): 145–154, 1979.

    CAS  Google Scholar 

  27. Johnson, JT, Barnes EL, Myers EN, Schramm VL Jr, Borochovitz D, Sigler B. The extracapsular spread of tumors in cervical node metastasis. Arch Otolaryngol (107): 725–729, 1981.

    PubMed  CAS  Google Scholar 

  28. Snow GB, Annyas AA, van Slooten EA, Bartelink H, Hart AAM. Prognostic factors of neck node metastasis. Clin Otolaryngol (7): 185–192, 1982.

    Article  PubMed  CAS  Google Scholar 

  29. Carenfelt C, Eliasson K. Radical neck dissection and permanent sequelae associated with spinal accessory nerve injuries. Acta Otolaryngol (91): 155–160, 1981.

    Article  Google Scholar 

  30. Dargent M, Papillon J. Résultats éloignés de l’évidement ganglionaire du cou avec conservation du filet mentonier et du spinal. Lyon Chir (41): 715–721, 1945.

    Google Scholar 

  31. Pietrantoni L, Fior R. Clinical and surgical problems of cancer of larynx and hypopharynx. Acta Otolaryngol, Suppl. 142, 1958.

    Google Scholar 

  32. Carenfelt C, Eliasson K. Cervical metastases following radical neck dissection that preserved the spinal accessory nerve. Head & Neck Surg (2): 181–184, 1980.

    Article  CAS  Google Scholar 

  33. Brandenburg JH, Lee CYS. The eleventh nerve in radical neck dissection. Laryngoscope (91): 1851–1858, 1981.

    Article  PubMed  CAS  Google Scholar 

  34. Schuller DE, Platz CE, Krause CJ. Spinal accessory lymph nodes: A prospective study of metastatic involvement. Laryngoscope (88): 439–451, 1978.

    Article  PubMed  CAS  Google Scholar 

  35. Skolnik EM, Yee KF, Friedman M, Golden TA. The posterior triangle in radical neck surgery. Arch Otolaryngol (102): 1–4, 1976.

    PubMed  CAS  Google Scholar 

  36. Nahum, AM. Radical neck dissection: Theme and variations. Head & Neck Surg (2): 179–180, 1980.

    Article  CAS  Google Scholar 

  37. Becker GD, Pareil GJ. Technique of preserving the spinal accessory nerve during radical neck dissection. Laryngoscope (89): 827–831, 1979.

    PubMed  CAS  Google Scholar 

  38. Carenfelt C, Eliasson K. Occurrence, duration and prognosis of unexpected accessory nerve paresis in radical neck dissection. Acta Otolaryngol (90): 470–473, 1980.

    Article  PubMed  CAS  Google Scholar 

  39. Saunders WH, Johnson EW. Rehabilitation of the shoulder after radical neck dissection. Ann Otol (84): 812–816, 1975.

    CAS  Google Scholar 

  40. Chu W, Strawitz JG. Results in suprahyoid, modified radical and standard radical neck dissection for metastatic squamous cell carcinoma: Recurrence and survival. Amer J Surg (136): 512–515, 1978.

    Article  PubMed  CAS  Google Scholar 

  41. Jesse RH. Modified neck dissection with and without radiation. In Head and Neck Oncology, Controversies in Cancer Treatment, Kagan AR, Miles JW (eds). Boston: G.K. Hall, 1981, pp. 247–254.

    Google Scholar 

  42. Cachin Y, Eschwege F. Combination of radiotherapy and surgery in the treatment of head and neck cancers. Cancer Treatm Rev (2): 177–191, 1975.

    Article  CAS  Google Scholar 

  43. Terz JJ, Lawrence W Jr. Ineffectiveness of combined radiation and surgery in the management of malignancies of the oral cavity, larynx and pharynx. In Head and Neck Oncology, Controversies in Cancer Treatment, Kagan AR, Miles JW (eds). Boston: G.K. Hall, 1981, pp. 111–123.

    Google Scholar 

  44. Carpenter RJ III, De Santo LW, Devine KD et al. Cancer of the hypopharynx: Analysis of treatment and results in 162 patients. Arch Otolaryngol (102): 716–721, 1976.

    PubMed  Google Scholar 

  45. Schuller DE, McGuirt WF, Krause CJ, McGabe BF, Pflug BK. Increased survival with surgery alone vs. combined therapy. Laryngoscope (89): 582–594, 1979.

    Article  PubMed  CAS  Google Scholar 

  46. Strong MS, Vaughan CW, Kayne HL, Aral IM, Ucmakli A, Feldman M, Healy GB. A randomized trial of preoperative radiotherapy in cancer of the oropharynx and hypopharynx. Amer J Surg (136): 494–500, 1978.

    Article  PubMed  CAS  Google Scholar 

  47. Hintz B, Charynler K, Chandler JR, Sudarsanam A, Garciga C. Randomized study of control of the primary tumor and survival using preoperative radiation, radiation alone, or surgery alone in head and neck carcinomas. J Surg Oncol (12): 75–85, 1979.

    Article  PubMed  CAS  Google Scholar 

  48. Terz JJ, King ER, Lawrence WJr. Preoperative irradiation for head and neck cancer: Results of a prospective study. Surgery (89): 449–453, 1981.

    PubMed  CAS  Google Scholar 

  49. Jesse RH, Lindberg RD. The efficacy of combining radiation therapy with a surgical procedure in patients with cervical metastasis from squamous cancer of the oropharynx and hypopharynx. Cancer (35): 1163–1166, 1975.

    Article  PubMed  CAS  Google Scholar 

  50. Vandenbrouck C, Sancho H, Le Fut R, Richard JM, Cachin Y. Results of a randomized clinical trial of preoperative irradiation versus postoperative in treatment of tumors of the hypopharynx. Cancer (39): 1445–1449, 1977.

    Article  PubMed  CAS  Google Scholar 

  51. Marcus RB Jr, Million RR, Cassissi, NJ. Postoperative irradiation for squamous cell carcinomas of the head and neck: Analysis of time-dose factors related to control above the clavicles. Int J Radiat Oncol Biol Phys (5): 1943–1949, 1979.

    Article  PubMed  Google Scholar 

  52. Snow JB, Gelber RD, Kramer S, Davis LW, Marcial VA, Lowry LD. Comparison of preoperative and postoperative radiation therapy for patients with carcinoma of the head and neck. Acta Otolaryngol (91): 611–626, 1981.

    Article  PubMed  CAS  Google Scholar 

  53. Bartelink H, Breur H, Hart G, Annyas AA, van Slooten WA, Snow GB. The value of postoperative radiotherapy as an adjuvant to radical neck dissection. Cancer (52): 1008–1013, 1983.

    Article  PubMed  CAS  Google Scholar 

  54. Beahrs OH, Barber KW. The value of radical dissection of structures of the neck in the management of carcinoma of the lip, mouth and larynx. Arch Surg (85): 49–56, 1962.

    PubMed  CAS  Google Scholar 

  55. Strong EW, Henschke UK, Nickson JJ, Frazell EL, Tollefsen R, Hilaris BS. Preoperative x-ray therapy as an adjunct to radical neck dissection. Cancer (19): 1509–1516, 1966.

    Article  PubMed  CAS  Google Scholar 

  56. Jesse RH, Fletcher GH. Treatment of the neck in patients with squamous cell carcinoma of the head and neck. Cancer (39): 868–872, 1977.

    Article  PubMed  CAS  Google Scholar 

  57. Vikram B. Importance of the time interval between surgery and postoperative radiation therapy in the combined management of head and neck cancer. Int J Radiat Oncol Biol Phys (5): 1837–1840, 1979.

    PubMed  CAS  Google Scholar 

  58. Versluis RJJ, Snow GB, Waal I van der. Preoperative administration of methotrexate in head and neck cancer. In press.

    Google Scholar 

  59. Kish J, Drelichman A, Weaver A, Jacobs J, Bergsman K, Al-sarraf M. Cis-platinum and 5-fluorouracil infusion in patients with recurrent and disseminated epidermoid cancer of the head and neck. Proc Amer Soc Clin Onc 1: 193, 1982.

    Google Scholar 

  60. Frazell EL. A review of the treatment of cancer of the mobile portion of the tongue. Cancer (28): 1178–1181, 1971.

    Article  PubMed  CAS  Google Scholar 

  61. White D, Byers RM. What is the preferred initial method of treatment for squamous carcinoma of the tongue? Amer J Surg (149): 553–555, 1980.

    Article  Google Scholar 

  62. Marks JE, Lee F, Freeman RB, Zivnuska FR, Ogura JH. Carcinoma of the oral tongue: A study of patient selection and treatment results. Laryngoscope (91): 1548–1559, 1981.

    Article  PubMed  CAS  Google Scholar 

  63. Spiro RH, Strong EW. Epidermoid carcinoma of the mobile tongue: Treatment by partial glossectomy alone. Amer J Surg (122): 707–710, 1971.

    Article  PubMed  CAS  Google Scholar 

  64. McGregor IA, McGrouther DA. Skin-graft reconstruction in carcinoma of the tongue. Head & Neck Surg (1): 47–51, 1978.

    Article  CAS  Google Scholar 

  65. Harrold CC Jr. Cancer of the tongue: Some comments on surgical treatment. In Symposium on Cancer of the Head and Neck; Total Treatment and Reconstructive Rehabilitation, vol II, Gaisford JC (ed). St. Louis: C.V. Mosby, 1969, pp. 185–190.

    Google Scholar 

  66. Vandenbrouck C, Sancho-Garnier H, Chassagne D, Saravane D, Cachin Y, Micheau C. Elective versus therapeutic radical neck dissection in epidermoid carcinoma of the oral cavity, results of a randomized clinical trial. Cancer (46): 386–390, 1980.

    Article  PubMed  CAS  Google Scholar 

  67. Spiro RH, Strong EW. Epidermoid carcinoma of the oral cavity and oropharynx. Elective vs. therapeutic radical neck dissection as treatment. Arch Surg (107): 382–384, 1973.

    PubMed  CAS  Google Scholar 

  68. Mendelson BC, Woods JE, Beahrs OH. Neck dissection in the treatment of carcinoma of the anterior two-thirds of the tongue. Surg Gyn Obst (143): 75–80, 1976.

    PubMed  CAS  Google Scholar 

  69. Whitehurst JO, Droulias CA. Surgical treatment of squamous cell carcinoma of the oral tongue. Arch Otolaryngol (103): 212–215, 1977.

    PubMed  CAS  Google Scholar 

  70. Johnson JT, Leipzig B, Cummings CW. Management of T1 carcinoma of the anterior aspect of the tongue. Arch Otolaryngol (106): 249–251, 1980.

    PubMed  CAS  Google Scholar 

  71. Moore C, Catiin D. Anatomic origins and locations of oral cancer. Amer J Surg (114): 510–513, 1967.

    Article  PubMed  CAS  Google Scholar 

  72. Helfrich GB, Nickels ME, El-Domeiri A, Das Gupta TK. Management of cancer of the floor of the mouth. Amer J Surg (124): 559–562, 1972.

    Article  PubMed  CAS  Google Scholar 

  73. Keim WF, Lowenberg S. Marginal mandibulectomy in treatment of carcinoma of the floor of the mouth. Laryngoscope (80): 1566–1579, 1970.

    Article  PubMed  CAS  Google Scholar 

  74. Harrold CC. Management of cancers of the floor of the mouth. Amer J Surg (122): 487–493, 1971.

    Article  PubMed  Google Scholar 

  75. Hardingham M, Dalley VM, Shaw HJ. Cancer of the floor of the mouth: Clinical features and results of treatment. Clin Oncology (3): 227–246, 1977.

    CAS  Google Scholar 

  76. Lederman M. The anatomy of cancer with special reference to tumours of the upper air and food passages. J Laryngol Otol (197): 181–208, 1964.

    Google Scholar 

  77. Ballard BR, Suess GR, Pickren JW, Greene GW Jr, Shedd DP. Squamous cell carcinoma of the floor of the mouth. Oral Surg Med Path (45): 568–579, 1978.

    Article  CAS  Google Scholar 

  78. Feind CR, Cole RM. Cancer of the floor of the mouth and its lymphatic spread. Amer J Surg (116): 482–287, 1968.

    Article  PubMed  CAS  Google Scholar 

  79. Guillamondegui OM, Oliver B, Hayden R. Cancer of the anterior floor of the mouth, selective choice of treatment and analysis of failures. Amer J Surg (140): 560–562, 1980.

    Article  PubMed  CAS  Google Scholar 

  80. Flynn MB, Mullins FX, Moore C. Selection of treatment in squamous carcinoma of the floor of the mouth. Amer J Surg (126): 477–481, 1973.

    Article  PubMed  CAS  Google Scholar 

  81. Guillamondegui OM, Jesse R. Surgical treatment of advanced carcinoma of the floor of the mouth. Am J Roentenol (126): 1256–1259, 1976.

    CAS  Google Scholar 

  82. Koison H, Spiro RH, Rosewit B, Lawson W. Epidermoid carcinoma of the floor of the mouth. Arch Otolaryngol (93): 280–283, 1971.

    Google Scholar 

  83. Lee ES, Wilson JSP. Carcinoma involving the lower alveolus. Brit J Surg (60): 85–107, 1973.

    Article  PubMed  CAS  Google Scholar 

  84. Whitehouse GH. Radiological bone changes produced by intraoral squamous carcinomata involving the lower alveolus. Clin Otolaryng (1): 45–52, 1976.

    Article  CAS  Google Scholar 

  85. Southam JC. The extension of squamous carcinoma along the inferior dental and neurovascular bundle. Br J Oral Surg (7): 137–145, 1970.

    Article  PubMed  CAS  Google Scholar 

  86. Weisman RA, Kimmelman CP. Bone scanning in the assessment of mandibular invasion by oral cavity carcinomas. Laryngoscope (92): 1–4, 1982.

    Article  PubMed  CAS  Google Scholar 

  87. Byers RM, Newman R, Russell N, Yue A. Results of treatment for squamous carcinoma of the lower gum. Cancer (47): 2236–2238, 1981.

    Article  PubMed  CAS  Google Scholar 

  88. Cady B, Catiin D. Epidermoid carcinoma of the gums. A 20-year survey. Cancer (3): 551–569, 1969.

    Article  Google Scholar 

  89. Nathansson A, Jakobsson PA, Wersäll J. Prognosis of squamous cell carcinoma of the gums. Acta Otolaryng (75): 301–303, 1973.

    Article  Google Scholar 

  90. Conley J. Squamous cell cancer of the buccal mucosa, a review of 90 cases. Arch Otolaryngol (97): 330–333, 1973.

    PubMed  CAS  Google Scholar 

  91. Vegers JWM, Show GB, v.d. Waal I. Squamous cell carcinoma of the buccal mucosa. A review of 85 cases. Arch Otolaryng (105): 192–195, 1979.

    PubMed  CAS  Google Scholar 

  92. Bloom ND, Spiro RH. Carcinoma of the cheek mucosa, a retrospective analysis. Amer J Surg (149): 556–559, 1980.

    Article  Google Scholar 

  93. Konrad HR, Canalis RE, Calcaterra TC. Epidermoid carcinoma of the palate. Arch Otolaryngol (104): 208–212, 1978.

    PubMed  CAS  Google Scholar 

  94. Eneroth CM, Hjertman L, Moberger G. Squamous cell carcinomas of the palate. Acta Otolaryng (73): 418–427, 1972.

    Article  PubMed  CAS  Google Scholar 

  95. Evans JF, Shah JP. Epidermoid carcinoma of the palate. Amer J Surg (142): 451–455, 1981.

    Article  PubMed  CAS  Google Scholar 

  96. Copeland EM, Daly JM, Dundrick SJ. Nutritional concepts in the treatment of head and neck malignancies. Head & Neck Surg (1): 350–363, 1979.

    Article  Google Scholar 

  97. Sobol SM, Conoyer JM, Zill R, Thawley SE, Ogura JH. Nutritional concepts in the management of the head and neck cancer patient. Laryngoscope (89): 962–979, 1979.

    PubMed  CAS  Google Scholar 

  98. Close LG. Indications for hyperalimentation in the treatment of head and neck malignancies. Otolaryngol Head Neck Surg (88): 700–706, 1980.

    Google Scholar 

  99. Daly JM, Dudrick SJ, Copeland EM. Parenteral nutrition in patients with head and neck cancer: Techniques and results. Otolaryngol Head Neck Surg (88): 707–713, 1980.

    PubMed  CAS  Google Scholar 

  100. Yarington CT Jr, Yonkers AJ, Beddoc GM. Radical neck dissection, mortality and morbidity. Arch Otolaryngol (97): 306–308, 1973.

    PubMed  Google Scholar 

  101. Simons JN, Beahrs OH, Woolner IB. Tumors of the submaxillary gland. Am J Surg (108): 485–494, 1964.

    Article  PubMed  CAS  Google Scholar 

  102. McGuirt WF, McCabe BF, Krause CJ. Complications of radical neck dissection: A survey of 788 patients. Head & Neck Surg (1): 481–487, 1979.

    Article  Google Scholar 

  103. Joseph DL, Shumrick DL. Risks of head and neck surgery in previously irradiated patients. Arch Otolaryngol (97): 381–384, 1973.

    PubMed  CAS  Google Scholar 

  104. Razack MS, Baffi R, Sako K. Bilateral radical neck dissection. Cancer (47): 197–199, 1981.

    Article  PubMed  CAS  Google Scholar 

  105. Beahrs OH. Complications of surgery for cancer of the head and neck. In Management of Surgical Complications, Artz CP, Hardy JD (eds). Philadelphia: Saunders, 1975, pp. 277–290.

    Google Scholar 

  106. McGuirt WF, Loevy S, McCabe BF, Krause CJ. The risks of major head and neck surgery in the aged population. Laryngoscope (87): 1378–1382, 1977.

    Article  PubMed  CAS  Google Scholar 

  107. Williams RG, Murtagh GP. Mortality in surgery for head and neck cancer. J Laryngol Otol (87): 431–440, 1973.

    PubMed  CAS  Google Scholar 

  108. Donald PJ. Complications of combined therapy in head and neck carcinomas. Arch Otolaryngol (104): 329–322, 1978.

    PubMed  CAS  Google Scholar 

  109. Smits RG, Krause CJ, McCabe BF. Complications associated with combined therapy of oral and pharyngeal neoplasms. Ann Otol (81): 496–500, 1972.

    Google Scholar 

  110. Krizek TJ, Ariyan S. Infection. In Complications of Head and Neck Surgery, Conley JJ (ed). Philadelphia: Saunders, 1979, pp. 99–123.

    Google Scholar 

  111. Daly TE, Drane JB. Dental care for irradiated patients. In Neoplasia of Head and Neck, Chicago: Year Book, 1974, pp. 225–232.

    Google Scholar 

  112. Conley JJ. Oropharyngocutaneous fistula. In Complications of Head and Neck Surgery, Conley JJ (ed). Philadelphia: Saunders, 1979, pp. 92–98.

    Google Scholar 

  113. Shumrick DA. Carotid artery rupture. Laryngoscope (83): 1051–1061, 1973.

    Article  PubMed  CAS  Google Scholar 

  114. Conley JJ. Carotid artery ligation. In Complications of Head and Neck Surgery, Conley JJ (ed). Philadelphia: Saunders, 1979, pp. 81–91.

    Google Scholar 

  115. Conley JJ. Tracheostomy complications. In Complications of Head and Neck Surgery, Conley JJ (ed). Philadelphia: Saunders, 1979, pp. 274–292.

    Google Scholar 

  116. Neel HB III, Ketcham AS, Hammond WG. Requisites for successful cryogenic surgery of cancer. Arch Surg (102): 45–48, 1971.

    PubMed  Google Scholar 

  117. De Santo LW. The curative, palliative and adjunctive uses of cryosurgery in the head and neck. Laryngoscope (82): 1282–1291, 1972.

    Article  Google Scholar 

  118. Chandler JR. Cryosurgery for recurrent cancer of the head and neck. Otolaryngol Clin N Am (7): 193–204, 1974.

    CAS  Google Scholar 

  119. Gage AA. Five-year survival following cryosurgery for oral cancer. Arch Surg (111): 990–994, 1976.

    PubMed  CAS  Google Scholar 

  120. Smith DB, Weaver AW. Cryosurgery for oral cancer, a six-year retrospective study. J Oral Surg (34): 245–248, 1976.

    PubMed  CAS  Google Scholar 

  121. Bekke JPH, Baart JA. Six years’ experience with cryosurgery in the oral cavity. Int J Oral Surg (8): 251–270, 1979.

    Article  PubMed  CAS  Google Scholar 

  122. Bradley, PF. Modern trends in cryosurgery of bone in the maxillofacial region. Int J Oral Surg (7): 405–415, 1978.

    Article  PubMed  CAS  Google Scholar 

  123. Mihashi S, Jako GJ, Incze J, Strong MS, Vaughan CW. Laser surgery in otolaryngology: Interaction of CO2 laser and soft tissues. Bull NY Acad Sci (267): 263–294, 1975.

    Article  Google Scholar 

  124. Oosterhuis JW, Verschueren RCJ, Eibergen R, Oldhoff J. The viability of cells in the waste products of CO2-laser evaporation of Cloudman mouse melanomas. Cancer (49): 61–68, 1982.

    Article  PubMed  CAS  Google Scholar 

  125. Strong MS, Vaughan CW, Jealy GB, Shapshay SM, Jako GJ. Transoral management of localised carcinoma of the oral cavity using the CO2 laser. Laryngoscope (89): 897–905, 1979.

    Article  PubMed  CAS  Google Scholar 

  126. Strong MS, Vaughan CW, Jako GJ, Polanyi T. Transoral resection of cancer of the oral cavity: The role of the CO2 laser. Otolaryngol Clin North Am (12): 207–218, 1979.

    PubMed  CAS  Google Scholar 

  127. Carruth JAS. Resection of the tongue with the carbon dioxide laser. J Laryngol Otol (96): 529–543, 1982.

    Article  PubMed  CAS  Google Scholar 

  128. Carruth JAS, McKenzie AL, Wainwright AC. The carbon dioxide laser: Safety aspects. J Laryngol Otol (94): 411–417.

    Google Scholar 

  129. Chaudhry AP, Vickers RA, Gorlin RJ. Intraoral minor salivary gland tumors. An analysis of 1414 cases. Oral Surg. (14): 1194–1226, 1961.

    Article  PubMed  CAS  Google Scholar 

  130. Spiro RH, Koss PG, Hadju S, Strong EW. Tumors of minor salivary origin. A clinicopathologic study of 492 cases. Cancer (31): 117–129, 1973.

    Article  PubMed  CAS  Google Scholar 

  131. Snow GB. Tumours of the parotid gland. Clin. Otolaryngol (4): 457–467, 1979.

    CAS  Google Scholar 

  132. Conley J, Dingman DL. Adenoid cystic carcinoma in the head and neck (cylindroma). Arch Otolaryngol (100): 81–90, 1974.

    PubMed  CAS  Google Scholar 

  133. Chaudhry AP, Hampel A, Gorlin RJ. Primary malignant melanoma of the oral cavity. Cancer (11): 923–928, 1958.

    Article  PubMed  CAS  Google Scholar 

  134. Conley J, Pack GT. Melanoma of the mucous membranes of the head and neck. Arch Otolaryngol (99): 315–319, 1974.

    PubMed  CAS  Google Scholar 

  135. Shah JP, Huvos AG, Stron EW. Mucosal melanoma of the head and neck. Amer J Surg (134): 531–535, 1977.

    Google Scholar 

  136. Snow GB, van der Esch EP, van Slooten EA. Mucosal melanoma of the head and neck. Head & Neck Surg (1): 24–30, 1978.

    Article  CAS  Google Scholar 

  137. Eneroth CM, Lundberg C. Mucosal malignant melanomas of the head and neck. Laryngoscope (87): 760–764, 1976.

    Google Scholar 

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© 1984 Martinus Nijhoff Publishing, Boston

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Snow, G.B. (1984). Surgical Treatment of Malignant Tumors of the Oral Cavity. In: van der Waal, I., Snow, G.B. (eds) Oral Oncology. Developments in Oncology, vol 20. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2845-2_5

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  • DOI: https://doi.org/10.1007/978-1-4613-2845-2_5

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