Abstract
Four groups of Wistar rats, each consisting of 20 of both sexes were tested for carcinogenic potential at dose levels of 0 (negative control), 5, 25, and 125 ppm of pure γ-BHC (99.9% purity, determined by gas liquid chromatography) respectively by feeding for 27 months. The background level of γ-BHC was 0.005 ppm and 0.012 ppm for oc-BHC in the semi-synthetic feeds. In addition to routine necropsy and histopathology procedures, the BHC contents in the liver, kidney, brain, testes and adipose tissue were analyzed.
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© 1984 Plenum Press, New York
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Xu, J.K., Xu, F.D., Xu, S.L., Liu, Z.L., Wang, S.Q., Dai, Y. (1984). Study on the Carcinogenecity of γ-Benzene-Hexachloride in Rats. In: Chu, E.H.Y., Generoso, W.M. (eds) Mutation, Cancer, and Malformation. Environmental Science Research, vol 31. Springer, Boston, MA. https://doi.org/10.1007/978-1-4613-2399-0_78
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DOI: https://doi.org/10.1007/978-1-4613-2399-0_78
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4612-9463-4
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