Abstract
The terminal phase of chronic myeloid leukemia (CML) is often characterized by an accumulation of immature cells. The differentiation stage of these immature cells can vary considerably, however.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Similar content being viewed by others
References
Bettelheim, P., D. Lutz, O. Majdic, E. Paietta, O. Haas, W. Linkesch, E. Neumann, L. Lechner, and W. Knapp. 1985. Cell lineage heterogeneity in blast crisis of chronic myeloid leukaemia. Brit. J. Haematol., 59: 395.
Bettelheim, P., E. Paietta, O. Majdic, H. Gadner, J. Schwarzmeier, and W. Knapp. 1982. Expression of a myeloid marker on TdT-positive acute lymphocytic leukemic cells: evidence by double-fluorescence staining. Blood 60: 1392.
Majdic, O., K. Liszka, D. Lutz, and W. Knapp. 1981. Myeloid differentiation antigen defined by a monoclonal antibody. Blood 58: 1127.
Majdic, O., P. Bettelheim, H. Stockinger, W. Aberer, K. Liszka, D. Lutz, and W. Knapp. 1984. M2, a novel myelomonocytic cell surface antigen and its distribution on leukemic cells. Int. J. Cancer 33: 617.
Knapp, W., O. Majdic, H. Stockinger, P. Bettelheim, K. Liszka, U. Koller, and C. Peschel. 1984. Monoclonal antibodies to human myelomonocytic differentiation antigens in the diagnosis of acute myeloid leukemia. Med. Oncol. Tum. Pharmacother., 1: 257.
Sugimoto, T., E. Tatsumi, K. Takeda, K. Minato, K. Sagawa, and I. Minowada. 1984. Modulation of cell surface antigens induced by 12-O-tetradeca- noylphorbol 13-acetate in two myeloblasts cell lines, a promyelocyte cell line, and a monoblastic cell line: Detection with five monoclonal antibodies. J. Natl. Cancer Inst. 72: 923.
Griffin, J.D., and S.F. Schlossman. 1984. Expression of myeloid differentiation antigens in acute myeloblasts leukemia. In: Leucocyte ty**, A. Bernard, L. Boumsell, J. Dausset, C. Milstein, and S.F. Schlossman, eds. Springer-Verlag, Berlin, Heidelberg, p. 404–410.
Ugolini, V., G. Nunez, R.G. Smith, P. Stastny, and J.D. Capra. 1980. Initial characterization of monoclonal antibodies against human monocytes. Proc. Natl Acad. Sei. U.S.A. 77: 6764.
Majdic, O., P. Bettelheim, K. Liszka, and D. Lutz. 1982. Leukämiediagnostik mit monoklonalen Antikörpern. Wr. Klin. Wochenschr. 94: 387.
Liszka, K., O. Majdic, P. Bettelheim, and W. Knapp. 1983. Glycophorin A expression in malignant hematopoiesis. Am. J. Haematol. 15: 219.
Anstee, D.J., and P.A.W. Edwards. 1982. Monoclonal antibodies to human erythrocytes. Eur. J. Immunol. 12: 228.
McMichael, A.J., N.A. Rust, J.R. Pilch, R. Sochynsky, J. Morton, D.Y. Mason, C. Ruan, G. Tobelem, and J. Caen. 1981. Monoclonal antibody to human platelet glycoprotein I. Brit. J. Haematol. 49: 501.
Vainchenker, W., J.F. Deschamps, J.M. Bastin, J. Guichard, M. Titeux, J. Breton-Gorius, and A.J. McMichael. 1982. Two monoclonal antiplatelet antibodies as markers of human megakaryocyte maturation: immunofluorescent staining and platelet peroxidase detection in megakaryocyte colonies and in vivo cells from normal and leukemic patients. Blood 59: 514.
Tetteroo, P.A.T., P.M. Lansdorp, O.C. Leeksma, and A.E.G.K. von dem Borne. 1982. Monoclonal antibodies against human platelet glycoprotein Ilia. Brit. J. Haematol. 55: 509.
Tetteroo, P.A.T., F. Massaro, A. Muder, R. Schreuder van Gelder, and A.E.G.K. von dem Borne. 1984. Megakaryoblastic differentiation of pro- erythroblystic K562 cell-line cells. Leuk. Res., 8: 197.
Vodinelich, L., W. Tax, Y. Bai, S. Pegram, P. Capel, and M.F. Greaves. 1983. A monoclonal antibody (WT1) for detecting leukemias of T-cell precursors (T-ALL). Blood 62: 1108.
Reinherz, E.L., P.C. Kung, G. Goldstein, and S.F. Schlossman. 1979. A monoclonal antibody with selective reactivity with functionally mature human thymocytes and all peripheral human T cells. J. Immunol. 123: 1312.
Kung, P.C., M.A. Talle, M. DeMaria, M. Butler, J. Lifter, and G. Goldstein. 1980. Strategies for generating monoclonal antibodies defining human T lymphocyte differentiation antigens. Transplant. Proc. 12 (suppl.): 141.
Kamoun, M., P.J. Martin, J.A. Hansen, M.A. Brown, A.W. Siedak, and R.C. Nowinski. 1981. Identification of a human T lymphocyte surface protein associated with the E-rosette receptor. J. Exp. Med. 153: 207.
McMichael, A.J., J.R. Rilch, G. Galfre, D.Y. Mason, J.W. Fabre, and C. Milstein. 1979. A human thymocyte antigen defined by a hybrid myeloma monoclonal antibody. Eur. J. Immunol. 9: 205.
Ledbetter, J.A., R.L. Evans, M. Lipinski, C. Cunningham-Rundles, R.A. Good, and L.A. Herzenberg. 1981. Evolutionary conservation of surface molecules that distinguish T lymphocyte helper/inducer and T cytotoxic/suppressor subpopulations in mouse and man. J. Exp. Med. 153: 310.
Evans, R.L., D.W. Wall, C.D. Platsoucas, F.P. Siegal, S.M. Fikrig, C.M. Testa, and R.A. Good. 1981. Thymus-dependent membrane antigens in man: Inhibition of cell-mediated lympholysis by monoclonal antibodies to Th2 antigens. Proc. Natl. Acad. Sci. U.S.A. 78: 544.
Knapp, W., O. Majdic, P. Bettelheim, and K. Liszka. 1982. VIL-A1, a monoclonal antibody reactive with common acute lymphatic leukemia cells. Leuk. Res. 6: 137.
Forster, K.K., F.G. Gudat, Marie F. Girard, Renate Albrecht, J. Schmidt, C. Ludwig, and J.-P. Obrecht. 1982. Monoclonal antibody against a membrane antigen characterizing leukemic human B-lymphocytes. Cancer Res. 42: 1927.
Greaves, M.F., C. Sieff, and P.A.W. Edwards. 1983. Monoclonal anti-glycophorin as a probe for erythroleukemias. Blood 61: 645.
Bai, Y., H. Durbin, and N. Hogg. 1984. Monoclonal antibodies specific for platelet glycoproteins react with human monocytes. Blood 64: 139.
Robinson, J., C. Sieff, D. Delia, P.A.W. Edwards, and M. Greaves. 1981. Expression of cell-surface HLA-DR, HLA-ABC and glycophorin during erythroid differentiation. Nature 289: 68.
Hughes, A., B.A. McVerry, H. Walker, K.F. Bradstock, A.V. Hoffbrand, and G. Janossy. 1981. Heterogeneous blast cell crisis in Philadelphia negative chronic granulocytic leukaemia. Brit. J. Haematol. 47: 563.
Greaves, M.F. 1982. Target cells differentiation and clonal evolution in chronic granulocytic leukemia: a ‘model’ for understanding the biology of malignancy. In: Chronic granulocytic leukemia. M.T. Shaw, ed. Praeger, New York, p. 15–47.
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1986 Springer-Verlag New York Inc.
About this paper
Cite this paper
Bettelheim, P., Lutz, D., Majdic, O., Haas, O., Knapp, W. (1986). Frequent Detection of Erythroid and Platelet Antigens in Myeloid Blast Crisis of CML. In: Reinherz, E.L., Nadler, L.M., Haynes, B.F., Bernstein, I.D. (eds) Leukocyte Ty** II. Springer, New York, NY. https://doi.org/10.1007/978-1-4612-4850-7_25
Download citation
DOI: https://doi.org/10.1007/978-1-4612-4850-7_25
Publisher Name: Springer, New York, NY
Print ISBN: 978-1-4612-9329-3
Online ISBN: 978-1-4612-4850-7
eBook Packages: Springer Book Archive