A Gln to Arg Substitution in the Adducin Family of Proteins is a Necessary but not Sufficient Factor for High Blood Pressure in Rats of the Milan Hypertensive Strain

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Cellular and Molecular Biology of Atherosclerosis

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Abstract

Previous studies have shown that erythrocytes from the Milan hypertensive strain of rats (MHS) differ from the control normotensive strains (MNS). These differences are determined within the stem cells, are genetically associated with the development of hypertension, and are similar to those found between the tubular cells of the two strains. This alteration seems to be associated with abnormalities of membrane skeleton (Bianchi et al. 1985; Ferrari et al. 1986, 1987; Bianchi et al. 1990).

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© 1992 Springer-Verlag London Limited

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Baralle, F.E. (1992). A Gln to Arg Substitution in the Adducin Family of Proteins is a Necessary but not Sufficient Factor for High Blood Pressure in Rats of the Milan Hypertensive Strain. In: Gotto, A.M. (eds) Cellular and Molecular Biology of Atherosclerosis. Argenteuil Symposia. Springer, London. https://doi.org/10.1007/978-1-4471-1909-8_10

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  • DOI: https://doi.org/10.1007/978-1-4471-1909-8_10

  • Publisher Name: Springer, London

  • Print ISBN: 978-1-4471-1911-1

  • Online ISBN: 978-1-4471-1909-8

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