Abstract
Environmental quality assessment is an extensive field of research due to the permanent increase of the stringency imposed by the legislative framework. To complete the wide panel of measurement methods, essentially based on physicochemical tools, some scientists focused on the development of alternative biological methods such as those based on the use of bioluminescent bacteria biosensors. The first report dedicated to the development of such biosensors dates back to 1967 and describes an analytical system designed to address the problem of air toxicity assessment. Nevertheless the available technologies in the photosensitive sensors field were not mature enough and, as a result, limited biosensor development possibilities. For about 20 years, the wide democratisation of photosensors coupled with advances in the genetic engineering field have allowed the expansion of the scope of possibilities of bioluminescent bacterial biosensors, allowing a significant emergence of these biotechnologies. This chapter retraces the history of the main technological evolutions that bacterial bioluminescent biosensors have known over the last two decades.
![](http://media.springernature.com/lw685/springer-static/image/chp%3A10.1007%2F10_2015_333/MediaObjects/332058_1_En_333_Figa_HTML.gif)
Graphical Abstract
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Similar content being viewed by others
References
Thevenot DR, Toth K, Durst RA, Wilson GS (2001) Electrochemical biosensors: recommended definitions and classification. Biosens Bioelectron 16:121–131
Belkin S (2003) Microbial whole-cell sensing systems of environmental pollutants. Curr Opin Microbiol 6:206–212
Strehler BL (1959) Some optical properties of luminous bacteria. Arch Biochem Biophys 85:391–408
Serat WF, Budinger FE Jr, Mueller PK (1967) Toxicity evaluation of air pollutants by use of luminescent bacteria. Atmospheric Environ 1967(1):21–32
Heitzer A, Malachowsky K, Thonnard JE, Bienkowski PR et al (1994) Optical biosensor for environmental on-line monitoring of naphthalene and salicylate bioavailability with an immobilized bioluminescent catabolic reporter bacterium. Appl Env Microbiol 60:1487–1494
Iams H, Salzberg B (1935) The secondary emission phototube. Proc Inst Radio Eng 23:55–64
Mölders H (1990) Methods for detecting the presence of mercury using microorganisms with mercury-enhanced bioluminescence
Bjerketorp J, Hakansson S, Belkin S, Jansson JK (2006) Advances in preservation methods: kee** biosensor microorganisms alive and active. Curr Opin Biotechnol 17:43–49
Melamed S, Elad T, Belkin S (2012) Microbial sensor cell arrays. Curr Opin Biotechnol 23:2–8
Wang X, Lu X, Chen J (2014) Development of biosensor technologies for analysis of environmental contaminants. Trends Environ Anal Chem 2:25–32
Engstrom RW (1980) Photomultiplier handbook. RCA Corp
Iams HE, Salzberg B (1935) The secondary emission phototube. Proc IRE 23:55–64
Zworykin VK, Morton GA, Malter L (1936) The secondary emission multiplier—a new electronic device. Proc Inst Radio Eng 24:351–375
Beijerinck MW (1889) Le Photobacterium luminosum, Bactérie lumineuse de la Mer du Nord. Arch Néerl Sci Exactes Nat 401–27
Carmi OA, Stewart GS, Ulitzur S, Kuhn J (1987) Use of bacterial luciferase to establish a promoter probe vehicle capable of nondestructive real-time analysis of gene expression in Bacillus spp. J Bacteriol 169:2165–2170
Polyak B, Bassis E, Novodvorets A, Belkin S et al (2001) Bioluminescent whole cell optical fiber sensor to genotoxicants: system optimization. Sens Actuators B Chem 74:18–26
Ivask A, Green T, Polyak B, Mor A et al (2007) Fibre-optic bacterial biosensors and their application for the analysis of bioavailable Hg and As in soils and sediments from Aznalcollar mining area in Spain. Biosens Bioelectron 22:1396–1402
Hakkila K, Green T, Leskinen P, Ivask A et al (2004) Detection of bioavailable heavy metals in EILATox-Oregon samples using whole-cell luminescent bacterial sensors in suspension or immobilized onto fibre-optic tips. J Appl Toxicol 24:333–342
Cheol Gil G, Mitchell RJ, Tai Chang S, Bock Gu M (2000) A biosensor for the detection of gas toxicity using a recombinant bioluminescent bacterium. Biosens Bioelectron 15:23–30
Gu MB, Chang ST (2001) Soil biosensor for the detection of PAH toxicity using an immobilized recombinant bacterium and a biosurfactant. Biosens Bioelectron 16:667–674
Chang ST, Lee HJ, Gu MB (2004) Enhancement in the sensitivity of an immobilized cell-based soil biosensor for monitoring PAH toxicity. Sens Actuators B Chem 97:272–276
Yolcubal I, Piatt JJ, Pierce SA, Brusseau ML et al (2000) Fiber optic detection of in situ lux reporter gene activity in porous media: system design and performance. Anal Chim Acta 422:121–130
Valdman E, Gutz IGR (2008) Bioluminescent sensor for naphthalene in air: cell immobilization and evaluation with a dynamic standard atmosphere generator. Sens Actuators B Chem 133:656–663
Horry H, Charrier T, Durand MJ, Vrignaud B et al (2007) Technological conception of an optical biosensor with a disposable card for use with bioluminescent bacteria. Sens. Actuators B Chem 122:527–534
Mendis S, Kemeny SE, Fossum ER (1994) CMOS active pixel image sensor. IEEE Trans Electron Devices 41:452–453
Simpson ML, Sayler GS, Applegate BM, Ripp S et al (1998) Bioluminescent-bioreporter integrated circuits form novel whole-cell biosensors. Trends Biotechnol 16:332–338
Lee JH, Mitchell RJ, Kim BC, Cullen DC et al (2005) A cell array biosensor for environmental toxicity analysis. Biosens Bioelectron 21:500–507
Sakaguchi T, Morioka Y, Yamasaki M, Iwanaga J et al (2007) Rapid and onsite BOD sensing system using luminous bacterial cells-immobilized chip. Biosens Bioelectron 22:1345–1350
Roda A, Cevenini L, Michelini E, Branchini BR (2011) A portable bioluminescence engineered cell-based biosensor for on-site applications. Biosens Bioelectron 26:3647–3653
Charrier T, Chapeau C, Bendria L, Picart P et al (2011) A multi-channel bioluminescent bacterial biosensor for the on-line detection of metals and toxicity. Part II: technical development and proof of concept of the biosensor. Anal Bioanal Chem 400:1061–1070
Tani H, Maehana K, Kamidate T (2004) Chip-based bioassay using bacterial sensor strains immobilized in three-dimensional microfluidic network. Anal Chem 76:6693–6697
Jouanneau S, Durand MJ, Thouand G (2012) Online detection of metals in environmental samples: comparing two concepts of bioluminescent bacterial biosensors. Environ Sci Technol 46:11979–11987
Affi M, Solliec C, Legentillomme P, Comiti J et al (2009) Numerical design of a card and related physicochemical phenomena occurring inside agarose-immobilized bacteria: A valuable tool for increasing our knowledge of biosensors. Sens Actuators B Chem 138:310–317
Gu MB, Dhurjati PS, Van Dyk TK, LaRossa RA (1996) A miniature bioreactor for sensing toxicity using recombinant bioluminescent escherichia coli cells. Biotechnol Prog 12:393–397
Gu MB, Gil GC, Kim JH (1999) A two-stage minibioreactor system for continuous toxicity monitoring. Biosens Bioelectron 14:355–361
Gu BM, Gil CG (2001) A multi-channel continuous toxicity monitoring system using recombinant bioluminescent bacteria for classification of toxicity. Biosens Bioelectron 16:661–666
Lee JH, Gu MB (2005) An integrated mini biosensor system for continuous water toxicity monitoring. Biosens Bioelectron 20:1744–1749
Horry H, Durand M-J, Picart P, Bendriaa L et al (2004) Development of a biosensor for the detection of tributyltin. Environ Toxicol 19:342–345
Ikariyama Y, Nishiguchi S, Koyama T, Kobatake E et al (1997) Fiber-optic-based biomonitoring of benzene derivatives by recombinant E. coli bearing luciferase gene-fused TOL-plasmid immobilized on the fiber-optic end. Anal Chem 69:2600–2605
Rabner A, Belkin S, Rozen R, Shacham Y (2006) Whole-cell luminescence biosensor-based lab-on-chip integrated system for water toxicity analysis. In: Proceedings of SPIE 6112, Microfluidics, BioMEMS, and medical microsystems vol IV, pp 611205–10
Choi SH, Gu MB (2002) A portable toxicity biosensor using freeze-dried recombinant bioluminescent bacteria. Biosens Bioelectron 17:433–440
Cho J-C, Park K-J, Ihm H-S, Park J-E et al (2004) A novel continuous toxicity test system using a luminously modified freshwater bacterium. Biosens. Bioelectron 20:338–344 (special issue honour Profr. Pierre Coulet)
Yagur-Kroll S, Schreuder E, Ingham CJ, Heideman R et al (2015) A miniature porous aluminum oxide-based flow-cell for online water quality monitoring using bacterial sensor cells. Biosens Bioelectron 64:625–632
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2015 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Jouanneau, S., Durand, M.J., Lahmar, A., Thouand, G. (2015). Main Technological Advancements in Bacterial Bioluminescent Biosensors Over the Last Two Decades. In: Thouand, G., Marks, R. (eds) Bioluminescence: Fundamentals and Applications in Biotechnology - Volume 3. Advances in Biochemical Engineering/Biotechnology, vol 154. Springer, Cham. https://doi.org/10.1007/10_2015_333
Download citation
DOI: https://doi.org/10.1007/10_2015_333
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-27405-8
Online ISBN: 978-3-319-27407-2
eBook Packages: Chemistry and Materials ScienceChemistry and Material Science (R0)