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References
Alexander B, Schnurrenberger PR, Brown RR (1981) Numbers of Brucella abortus in the placenta, umbilicus and fetal fluid of two naturally infected cows. Vet Rec 108:500
Allen MS, Wilgus JR, Chewning CS, Sayler GS, Simpson ML (2007) A destabilized bacterial luciferase for dynamic gene expression studies. Syst Synth Biol 1:3–9
Andreu N, Zelmer A, Wiles S (2011) Noninvasive biophotonic imaging for studies of infectious disease. FEMS Microbiol Rev 35:360–394
Carlton WM, Gleason ML, Braun EJ (1998) Ingress of Clavibacter michiganensis subsp. michiganensis into tomato leaves through hydathodes. Phytopathology 88:525–529
Chabot R, Kloepper JW, Antoun H, Beauchamp CJ (1996) Root colonization of maize and lettuce by bioluminescent Rhizobium leguminosarum biovar phaseoli. Appl Environ Microbiol 62:2767–2772
Chalupowicz L, Zellermann E-M, Fluegel M, Dror O, Eichenlaub R, Gartemann K-H, Savidor A, Sessa G, Iraki N, Barash I, Manulis-Sasson S (2012) Colonization and movement of GFP labeled Clavibactermichiganensis subsp. michiganensis during tomato infection. Phytopathology 102:23–31
Chang RJ, Ries SM, Pataky JK (1991) Dissemination of Clavibacter michiganensis subsp. michiganensis by practices used to produce tomato transplants. Phytopathology 81:1276–1281
Cirvilleri G, Lindow SE (1994) Differential expression of genes of Pseudomonas syringae on leaves and in culture evaluated with random genomic lux fusions. Mol Ecol 3:249–257
Cirvilleri G, BellaP CataraV (2000) Luciferase genes as a marker for Pseudomonas corrugata. J Plant Pathol 82:237–241
Contag CH, Contag PR, Mullins JI, Spilman SD, Stevenson DK, Benaron DA (1995) Photonic detection of bacterial pathogens in living hosts. Mol Microbiol 18:593–603
Contag PR (2008) Bioluminescence imaging to evaluate infections and host response in vivo. Methods Mol Biol 415:101–118
Corbel M (1997) Brucellosis: an overview. Emerg Infect Dis 3:213–221
Corish P, Tyler-Smith C (1999) Attenuation of green fluorescent protein half-life in mammalian cells. Protein Eng 12:1035–1040
Delrue RMM-LM, Lestrate P, Danese I, Bielarz V, Mertens P, De Bolle X, Tibor A, Gorvel JP, Letesson JJ (2001) Identification of Brucella spp. genes involved in intracellular trafficking. Cell Microbiol 3:487–497
De Weger LA, DunbarP MahafeeWF, LugtenbergJJ SaylerGS (1991) Use of bioluminescent markers to detect Pseudomonas spp. in the rhizosphere. Appl Environ Microbiol 57:3641–3644
Engebrecht J, Silverman M (1984) Identification of genes and gene products necessary for bacterial bioluminescence. Proc Natl Acad Sci USA 81:4154–4158
Eichenlaub R, Gartemann KH (2011) The Clavibacter michiganensis subspecies, molecular investigation of Gram-positive bacterial plant pathogens. Annu Rev Phytopathol 49:445–464
Essenberg R, Seshadri R, Nelson K, Paulsen I (2002) Sugar metabolism by Brucellae. Vet Microbiol 90:249–261
European and Mediterranean Plant Protection Organization (2005) Clavibacter michiganensis subsp. michiganensis. EPPO Bull 35:275–283
Fan J, Lamb C, Crooks C (2008) High-throughput quantitative luminescence assay of the growth in planta of Pseudomonas syringae chromosomally tagged with Photorhabdus luminescens luxCDABE. The Plant J 53:393–399
Fatmi M, Bolkan HA, Schaad NW (1991) Seed treatments for eradicating Clavibacter michiganensis subsp. michiganensis from naturally infected tomato seeds. Plant Dis 75:383–385
Foulongne VBG, Cazevieille C, Michaux-Charachon S, O’Callaghan D (2000) Identification of Brucella suis genes affecting intracellular survival in an in vitro human macrophage infection model by signature-tagged transposon mutagenesis. Infect Immun 68:1297–1303
Frackman S, Anhalt M, Nealson KH (1990) Cloning, organization, and expression of the bioluminescence genes of Xenorhabdus luminescens. J Bacteriol 172:5767–5773
Francis KP, Bellinger-Kawahara C, Joe D, Purchio TF, Hawkinson MJ, Contag PR (2000) Monitoring bioluminescent Staphylococcus aureus infections in living mice using a novel luxABCDEconstruction. Infect Immun 68:3594–3600
Franz DR (1999) Foreign animal disease agents as weapons in biological warfare. Ann NY Acad Sci 894:100–104
Fukui R, McElhaney R, Fukui H, Alvarez AM, Nelson SC (1996) Relationship between symptom development and actual sites of infection in leaves of anthurium inoculated with a bioluminescent strain of Xanthomonas campestris pv. dieffenbachiae. Appl Environ Microbiol 62:1021–1028
Gartemann KH, Kirchner O, Engemann J, Gräfen I, Eichenlaub R, Burger A (2003) Clavibacter michiganensis subsp. michiganensis: first steps in the understanding of virulence of a Gram-positive phytopathogenic bacterium. J Biotechnol 106:179–191
Gitaitis RD, Beaver RW, Voloudakis AE (1991) Detection of Clavibacter michiganensis subsp. michiganensis in symptomless tomato transplants. Plant Dis 75:834–838
Gleason ML, Ricker MD, Gitaitis RD (1993) Recent progress in understanding and controlling bacterial canker of tomato in Eastern North America. Plant Dis 77:1069–1076
Glomski IJ, Piris-Gimenez A, Huerre M, Mock M, Goossens PL (2007) Primaryinvolvement of pharynx and peyer’s patch in inhalational and intestinal anthrax. PLoS Pathog 3:e76
Glynn M, Lynn TV (2008) Brucellosis. J Amer Vet Med Assoc 233:900–908
Greer LF III, Szalay AA (2002) Imaging of light emission from the expression ofluciferases in living cells and organisms: a review. Luminescence 17:43–74
Griffiths MW (2000) How novel methods can help discover more information about foodborne pathogens. Can J Infect Dis 11:142–153
Hardy J, Francis KP, DeBoer M, Chu P, Gibbs K, Contag CH (2004) Extracellularreplication of Listeria monocytogenes in the murine gall bladder. Science 303:851–853
Hong PCTR, Ficht TA (2000) Identification of genes required for chronic persistence of Brucella abortus in mice. Infect Immun 68:4102–4107
Jahr H, Burger A, Bahro R, Eichenlaub R, Ahlemeyer J (1999) Interactions between Clavibacter michiganensis and its host plants. Environ Microbiol 1:113–118
Kamoun S, Kado CI (1990) A plant-inducible gene of Xanthomonas campestris pv. campestris encodes an exocellular component required for growth in the host and hypersensitivity on nonhosts. J Bacteriol 172:5165–5172
Kassem II, Sanad Y, Gangaiah D, Lilburn M, Lejeune J, Rajashekara G (2010) Use of bioluminescence imaging to monitor Campylobacter survival in chicken litter. J Appl Microbiol 109:1988–1997
Kaufmann AF, Meltzer MI, Schmid GP (1997) The economic impact of a bioterrorist attack: are prevention and postattack intervention programs justifiable? Emerg Infect Dis 3:83–94
Kirchner O, Gartemann KH, Zellermann EM, Eichenlaub R, Burger A (2001) A highlyefficient transposon mutagenesis system for the tomato pathogen Clavibacter michiganensis subsp. michiganensis. Mol Plant Microbe Interact 14:1312–1318
Ko J, Gendron-Fitzpatrick A, Ficht TA, Splitter GA (2002) Virulence criteria for Brucella abortus strains as determined by interferon regulatory factor 1-deficient mice. Infect Immun 70:7004–7012
Ko J, Gendron-Fitzpatrick A, Splitter GA (2002) Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis. J Immunol 168:2433–2440
Koc Z, Turunc T, Boga C (2007) Gonadal brucellar abscess: imaging and clinical findings in 3 cases and review of the literature. J Clin Ultrasound 35:395–400
Kulkarni R, Chunchanur SK, Ajantha GS, Shubhada C, Jain P (2009) Presumptive diagnosis of brucella epididymoorchitis by modified cold ZN staining of testicular pus sample. Indian J Med Res 130:484–486
Li Z, Szittner R, Meighen EA (1993) Subunit interactions and the role of the luxA polypeptide in controlling thermal stability and catalytic properties in recombinant luciferase hybrids. Biochim Biophys Acta 1158:137–145
Maudlin I, Weber S (2006) The control of neglected zoonotic diseases: a route to poverty alleviation. WHO, Geneva
Meighen E (1993) Bacterial bioluminescence: organization, regulation, and application of the lux genes. FASEB J 7:1016–1022
Meletzus D, Dreier J, Bermpohl A, Eichenlaub R (1993) Evidence for plasmid-encoded virulence factors in the phytopathogenic bacterium Clavibacter michiganensis subsp. michiganensis NCPPB382. J Bacteriol 175:2131–2136
Miller SA, Rowe RC, Riedel RM (1996) Bacterial spot, speck, and canker of tomatoes HYG-3120-96. Ohio State Univ Extension
O’Callaghan DCC, Allardet-Servent A, Boschiroli ML, Bourg G, Foulongne V, Frutos P, Kulakov Y, Ramuz M (1999) A homologue of the Agrobacterium tumefaciens VirB and Bordetella pertussis Ptl type IV secretion systems is essential for intracellular survival of Brucella suis. Mol Microbiol 33:1210–1220
Paynter CD, Arnold DL, Salisbury VC, Jackson RW (2006) The use of bioluminescence for monitoring in planta growth dynamics of a Pseudomonas syringae plant pathogen. Eur J Plant Pathol 115:363–366
Petersen E, Rajashekara G, Sanakkayala N, Eskra L, Harms J, Splitter G (2013) Erythritol triggers expression of virulence traits in Brucella melitensis. Microbes Infect 15:440–449
Radhakrishnan GKYQ, Harms JS, Splitter GA (2009) Brucella TIR domain-containing protein mimics properties of the toll-like receptor adaptor protein TIRAP. J Biol Chem 284:9892–9898
Rajashekara G, Glover DA, Banai M, O’Callaghan D, Splitter GA (2006) Attenuated bioluminescent Brucella melitensis mutants GR019 (virB4), GR024 (galE), and GR026 (BMEI1090-BMEI1091) confer protection in mice. Infect Immun 74:2925–2936
Rajashekara G, Glover DA, Krepps M, Splitter GA (2005) Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections. Cell Microbiol 7:1459–1473
Rajashekara G, Krepps M, Eskra L, Mathison A, Montgomery A, Ishii Y, Splitter G (2005) Unraveling Brucella genomics and pathogenesis in immunocompromised IRF-1-/- mice. Am J Reprod Immunol 54:358–368
Ricker MD, Riedel RM (1993) Effect of secondary spread of Clavibacter michiganensis subsp. michiganensis on yield of northern processing tomatoes. Plant Dis 77:364–366
Ritchie JM, Campbell GR, Shepherd J, Beaton Y, Jones D, Killham K, Artz RR (2003) A stable bioluminescent construct of Escherichia coli O157:H7 for hazard assessments of long-term survival in the environment. Appl Environ Microbiol 69:3359–3367
Samartino L, Enright FM (1993) Pathogenesis of abortion of bovine brucellosis. Comp Immunol Microbiol Infect Dis 16:95–101
Shaner NC, Steinbach PA, Tsien RY (2005) A guide to choosing fluorescent proteins. Nat Methods 2:905–909
Sharabani G, Manulis-Sasson S, Borenstein M, Shulhani R, Chalupowicz L, Lofthouse M, Shtienberg D (2013) The significance of guttation inthe secondary spread of Clavibactermichiganensis in tomato greenhouses. Plant Pathol 62:578–586
Sharabani G, Shtienberg D, Borenstein M, Shulhani R, Sofer M, Lofthouse M, Chalupowicz L, Barel V, Manulis-Sasson S (2012) Effects of plant age on disease development and virulence of Clavibacter michiganensis subsp. michiganensis on tomato. Plant Pathology 62:1114–1122
Shaw JJ, DaneF GeigerD, Kloepper JW (1992) Use of bioluminescence for detection of genetically engineered microorganisms released into the environment. Appl Environ Microbiol 58:267–273
Shaw JJ, Kado CI, Settles LG (1988) Transposon Tn4431 mutagenesis of Xanthomonas campestris pv. campestris: characterization of a non pathogenic mutant and cloning of a locus for pathogenicity. Mol Plant-Microbe Interact 1:39–45
Shirakawa T, Sasaki T, Ozaki K (1991) Ecology and control of tomato bacterial canker and detection methods of its pathogen. Jpn Agric Res Q 25:27–32
Sieira R, Comerci DJ, Sanchez DO, Ugalde RA (2000) A homologue of an operon required for DNA transfer in Agrobacterium is required in Brucella abortus for virulence and intracellular multiplication. J Bacteriol 182:4849–4855
Smith H, Williams AE, Pearce JH, Keppie J, Harris-Smith PW, Fitz-George RB, Witt K (1962) Foetal erythritol: a cause of the localization of Brucella abortus in bovine contagious abortion. Nature 193:47–49
Strider DL (1969) Bacterial canker of tomato, a literature review and bibliography. NC Agric Exp Stn Tech Bull 193:1–80
Szittner R, Meighen E (1990) Nucleotide sequence, expression, and properties of luciferase coded by lux genes from a terrestrial bacterium. J Biol Chem 265:16581–16587
Tancos MA, Chalupowicz L, Barash I, Manulis-Sasson S, Smart CD (2013) Tomato fruit and seed colonization by Clavibacter michiganensis subsp. michiganensis through external and internal routes. Appl Env Microbiol 79:6948–6957
Thorn RM, Nelson SM, Greenman J (2007) Use of a bioluminescent Pseudomonas aeruginosa strain within an in vitro microbiological system, as a model of wound infection, to assess the antimicrobial efficacy of wound dressings by monitoring light production. Antimicrob Agents Chemother 51:3217–3224
Tsiantos J (1987) Transmission of bacterium Corynebacterium michiganense pv. michiganense by seeds. J Phytopathology 119:142–146
Tsien RY (1998) The green fluorescent protein. Annu Rev Biochem 67:509–544
Vallejo JG, Stevens AM, Dutton RV, Kaplan SL (1996) Hepatosplenic abscesses due to Brucella melitensis: report of a case involving a child and review of the literature. Clin Infect Dis 22:485–489
Verkhusha VV, Lukyanov KA (2004) The molecular properties and applications of Anthozoa fluorescent proteins and chromoproteins. Nat Biotechnol 22:289–296
Waidmann MS, Bleichrodt FS, Laslo T, Riedel CU (2011) Bacterial luciferasereporters: the Swiss army knife of molecular biology. Bioeng Bugs 2:8–16
Widder EA (2010) Bioluminescence in the ocean: origins of biological, chemical, and ecological diversity. Science 328:704–708
Wiles S, Clare S, Harker J, Huett A, Young D, Dougan G, Frankel G (2004) Organ specificity, colonization and clearance dynamics in vivo following oral challenges with the murine pathogen Citrobacter rodentium. Cell Microbiol 6:963–972
Xu X, Miller SA, Baysal-Gurel F, Gartemann KH, Eichenlaub R, Rajashekara G (2010) Bioluminescence imaging of Clavibacter michiganensis subsp. michiganensis infection of tomato seeds and plants. Appl Environ Microbiol 76:3978–3988
Xu X, Rajashekara G, Paul PA, Miller SA (2012) Colonization of tomato seedlings by bioluminescent Clavibacter michiganensis subsp. michiganensis under different humidity regimes. Phytopathology. 102:177–184
Young E (1995) An overview of human brucellosis. Clin Infect Dis 21:283–289
Acknowledgment
Research in the Rajashekara and Miller laboratories is supported by funds from the Agriculture and Food Research Initiative (AFRI, USDA), the Specialty Crops Research Initiative (SCRI-2010-600-25320, USDA), the Ohio Agricultural Research and Development Center, and the Ohio State University.
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Kassem, I.I., Splitter, G.A., Miller, S., Rajashekara, G. (2014). Let There Be Light! Bioluminescent Imaging to Study Bacterial Pathogenesis in Live Animals and Plants. In: Thouand, G., Marks, R. (eds) Bioluminescence: Fundamentals and Applications in Biotechnology - Volume 3. Advances in Biochemical Engineering/Biotechnology, vol 154. Springer, Cham. https://doi.org/10.1007/10_2014_280
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