Overview
- Focuses on the regulation of transcription and translation in Archaea
- Summarizes recent advances in our understanding of RNA metabolism in Archaea at all levels
- Provides a panoramic view of enzymes, machines and pathways used to synthetize, modify and break down RNA in Archaea
- Highlights the advantage of using Archaea as model organisms to study fundamental molecular mechanisms across the three domains of life
Part of the book series: Nucleic Acids and Molecular Biology (NUCLEIC, volume 32)
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About this book
This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications of gene expression, it presents the current state of knowledge on archaeal RNA biology in 13 chapters. Topics covered include the modification and maturation of RNAs, the function of small non-coding RNAs and the CRISPR-Cas defense system. While Archaea have long been considered exotic microbial extremophiles, they are now increasingly being recognized as important model microorganisms for the study of molecular mechanisms conserved across the three domains of life, and with regard to the relevance of similarities and differences to eukaryotes and bacteria. This unique book offers a valuable resource for all readers interested in the regulation of gene expression in Archaea and RNA metabolism in general.
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Keywords
- Archaea
- transcription
- translation
- RNA processing
- ribonucleases
- non-coding RNAs
- CRISPR
- Archaea third domain of life
- RNA metabolism in Archaea
- extremophiles
- evolution of RNA biology
- RNA in Bacteria, Eukarya, Archaea
- archaeal tRNA rRNA
- archaeal RNA polymerase
- RNA-degrading enzymes in Archaea
- archaeal RNase P
- Evolution of C/D box sRNAs
- Haloarchaea
- methanogenic Archaea
- halophilic Archaea
Table of contents (11 chapters)
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Front Matter
Editors and Affiliations
About the editor
Béatrice Clouet-d'Orval, is a Research Director at the Centre de Biologie Intégrative, Toulouse (CBI/CNRS/Université de Toulouse). She received her degree in Genetics and Biochemistry from the Université Pierre et Marie Curie, Paris, and subsequently obtained an EMBO fellowship for postdoctoral research at the University of Colorado, Boulder.
Béatrice Clouet-d'Orval believes that the emergence of model organisms permitting genome-wide approaches that allow for the study of RNA biology in Archaea represents a unique opportunity to obtain major insights into evolutionary conserved RNA processing pathways in the three domains of life. Her research interests include in vitro reconstitution of archaeal ribonucleoprotein complexes involved in tRNA modification, and identification and characterization of archaeal enzymes involved in RNA processing and degradation. In addition, she is also active in promoting networking between scientists working on RNA and Archaea.
Bibliographic Information
Book Title: RNA Metabolism and Gene Expression in Archaea
Editors: Béatrice Clouet-d'Orval
Series Title: Nucleic Acids and Molecular Biology
DOI: https://doi.org/10.1007/978-3-319-65795-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer International Publishing AG 2017
Hardcover ISBN: 978-3-319-65794-3Published: 09 November 2017
Softcover ISBN: 978-3-319-88108-9Published: 18 May 2018
eBook ISBN: 978-3-319-65795-0Published: 28 October 2017
Series ISSN: 0933-1891
Series E-ISSN: 1869-2486
Edition Number: 1
Number of Pages: VIII, 269
Number of Illustrations: 12 b/w illustrations, 37 illustrations in colour
Topics: Nucleic Acid Chemistry, Microbiology, Protein Science, Enzymology