Abstract
Malnourished individuals have been reported to have characteristic electrically stimulated adductor pollicis muscle (APM) function tests: reduced maximal relaxation rate (MMR) and increased force at 10Hz in relation to 100Hz stimulation (F10/100) (Am J Clin Nutr 1982; 36: 602). We reexamined this observation and assessed the capacity of these tests to detect acute weight changes, performing 44 APM function tests in 30 cystic fibrosis (CF) patients, aged 17 to 34 years. Patients whose body weight/height ratio (W/H), the ratio of actual to ideal body weight (Lancet 1975; 2: 219), was 90% or below were defined as malnourished. MMR & F10/100 in the well-nourished subgroup were comparable to values previously reported in normal healthy individuals. In the malnourished subgroup (W/H 83±2% SEM) F10/100 was significantly increased (P<0.05), whereas, MMR did not differ between both subgroups. 14 patients were reexamined after a 3 month interval, four of which had changes in body weight of 2kg or more, however these were not associated with concomitant alterations in APM function.
In conclusion, our data confirms the observation that F10/100 is increased in malnourished individuals. However, neither F10/100 nor MMR are useful tests to follow the nutritional status of patients with CF.
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Szeinberg, A., Levy, L., Eraser, I. et al. 1845 ADDUCTOR POLLICIS MUSCLE FUNCTION TESTS IN CYSTIC FIBROSIS. Pediatr Res 19, 418 (1985). https://doi.org/10.1203/00006450-198504000-01863
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DOI: https://doi.org/10.1203/00006450-198504000-01863
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