Extended Data Fig. 7: Normal behavior in PHP.GFAP-IL-2-treated mice.
Behavioral assessment of wildtype mice treated with PHP.GFAP-GFP or PHP.GFAP-IL-2. a, Time spent on the rod, average of 4 repeated tests of 300 seconds (n = 15,15). b, Open field, total distance moved and time spent in the corners (n = 15,15). c, Nesting behavior (n = 15,15). d, Spatial learning in the Morris water maze. Path length to finding the hidden platform (n = 15,15). e, Probe tests after 5 days and 10 days and after reversal learning (n = 15,15). f, Freezing behavior over time during context acquisition conditioning (n = 15,15). g, Contextual discrimination during generalization test (n = 15,15). h, Sociability test trials to monitor the interaction with a stranger mouse (S1) compared to an empty chamber (E) (n = 15,15). Mean ± s.e.m. All experiments were repeated twice independently. Statistical analyses were performed using an unpaired two-tailed Student’s t-test.