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Directing mRNA export

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A recent study on the RNA-binding protein Npl3p reveals how its direct interaction with the mRNA export receptor Mex67p is regulated by phosphorylation and how this post-translational modification contributes to the assembly and disassembly of mRNP export complexes.

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Figure 1: Model for the phosphorylation and dephosphorylation cycles of Npl3p.

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  1. European Molecular Biology Laboratory (EMBL), Meyerhofstrasse 1, Heidelberg, D-69117, Germany

    Elisa Izaurralde

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  1. Elisa Izaurralde
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Izaurralde, E. Directing mRNA export. Nat Struct Mol Biol 11, 210–212 (2004). https://doi.org/10.1038/nsmb0304-210

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