A genome-wide association study has identified two new loci modifying pulmonary disease severity in cystic fibrosis. Although this data offers clues to pathways influencing pulmonary function, the underlying genes and mechanisms remain to be elucidated.
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Witt, H. New modifier loci in cystic fibrosis. Nat Genet 43, 508–509 (2011). https://doi.org/10.1038/ng.844
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DOI: https://doi.org/10.1038/ng.844
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