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Improved imputation of common and uncommon SNPs with a new reference set

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Figure 1: Imputation accuracy for individuals of European ancestry with the DCEG Reference Set and publicly available reference sets.

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Acknowledgements

The genoty** in the Multiethnic Cohort Study (MEC) was supported by a Department of Defense Breast Cancer Research Program Era of Hope Scholar Award (W81XWH-08-1-0383 to C.A.H.) and an NIH grant (CA132839).

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Authors and Affiliations

  1. Core Genoty** Facility, SAIC-Frederick, National Cancer Institute (NCI)-Frederick, Frederick, Maryland, USA

    Zhaoming Wang, Kevin B Jacobs, Meredith Yeager, Amy Hutchinson & **ang Deng

  2. Division of Cancer Epidemiology and Genetics, NCI, US National Institutes of Health (NIH), Bethesda, Maryland, USA

    Zhaoming Wang, Kevin B Jacobs, Meredith Yeager, Amy Hutchinson, Joshua Sampson, Nilanjan Chatterjee, Demetrius Albanes, Sonja I Berndt, Charles C Chung, **ang Deng, Ann W Hsing, Mark P Purdue, Phil Taylor, Margaret Tucker & Stephen J Chanock

  3. Epidemiology Research Program, American Cancer Society, Atlanta, Georgia, USA

    W Ryan Diver, Susan M Gapstur & Lauren R Teras

  4. Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA

    Christopher A Haiman, Brian E Henderson & Daniel Stram

  5. Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland

    Jarmo Virtamo

  6. Illumina, San Diego, California, USA

    Michael A Eberle & Jennifer L Stone

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  1. Zhaoming Wang
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  24. Stephen J Chanock
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Corresponding author

Correspondence to Stephen J Chanock.

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The authors declare no competing financial interests.

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Supplementary Text and Figures

Supplementary Methods, Supplementary Figures 1–3 and Supplementary Tables 1 and 2. (PDF 779 kb)

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Wang, Z., Jacobs, K., Yeager, M. et al. Improved imputation of common and uncommon SNPs with a new reference set. Nat Genet 44, 6–7 (2012). https://doi.org/10.1038/ng.1044

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