Abstract
Methyl jasmonate added at 100 μM on days 8, 14 and 20 to cultures of Taxus chinensis growing in flasks and 1 l airlift bioreactors improved taxuyunnanine C (TC) production by 50–60% in flasks and by about 80% in airlift bioreactors compared with single addition of 100 μM methyl jasmonate on day 8. The final TC production in the airlift bioreactors reached 565±47 mg l−1, which is the highest reported for taxoid production in a bioreactor.
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Wang, ZY., Zhong, JJ. Repeated elicitation enhances taxane production in suspension cultures of Taxus chinensis in bioreactors. Biotechnology Letters 24, 445–448 (2002). https://doi.org/10.1023/A:1014549008516
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DOI: https://doi.org/10.1023/A:1014549008516